Traditional Chinese medicine compound powder for treating stenocardia and preparation method thereof

Abstract

The invention discloses traditional Chinese medicine compound powder for treating stenocardia and a preparation method thereof. The compound powder is composed of the following ingredients: sandalwood, dutchmanspipe root, ligusticum wallichii, borneol, frankincense and storax. The preparation method comprises the following steps: carrying out the powder process; preparing a Beta-cyclodextrin inclusion compound of borneol; mixing the finished product to prepare into pills. The traditional Chinese medicine pills has the effects of regulating the flow of qi, relieving depression in the chest and relieving pain, can be used for treating stenocardia and chest distress; by adopting the Beta-cyclodextrin clathrate inclusion technology on borneol, stability of the drug is increased, and the loss of effective ingredients in the storage process is reduced; by conducting superfine grinding on the other ingredients, the solution absorption degree of the orally taken preparation in the body can be improved, the bioavailability of the drug is improved, the dosage is reduced, the raw materials are saved, the efficiency is improved, and the cost is reduced.

Description

technical field [0001] The invention belongs to the field of pharmacy, and in particular relates to a traditional Chinese medicine compound powder for treating angina pectoris and a preparation method thereof. Background technique [0002] Cardiovascular disease is one of the most common and serious diseases that endanger human health (especially middle-aged and elderly people). Dyslipidemia is an important risk factor for atherosclerosis, coronary heart disease and other cardiovascular and cerebrovascular diseases. Lipid-lowering drugs can reduce these The incidence and mortality of diseases have a positive and far-reaching impact on the prevention and treatment of cardiovascular diseases. According to the statistics of IMSHealth in the United States, the global lipid-lowering drug market has reached 33.849 billion US dollars in 2008, an increase of 1.75% over the previous year, accounting for 4.38% of the global pharmaceutical market, ranking second only to antineoplastic ...

AI Technical Summary

Problems solved by technology

[0003] Traditional Chinese medicine compound preparations for the treatment of angina pectoris often use various raw medicinal materials to be crushed into fine powder (above 80 mesh) and taken after mixing. Traditional Chinese medicine pills and powders account for a considerable proportion of solid preparations. The traditional processing technology makes the drug particle size 125-180 μm, which is not conducive to the full absorption of active ingredients, and has the disadvantages of high production cost and general drug utilization.

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