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Traditional Chinese medicine compound powder for treating stenocardia and preparation method thereof

A compound powder, angina pectoris technology, which is applied in the directions of pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc., can solve the problems of high production cost, unfavorable absorption of active ingredients, general drug utilization rate, and the like, Achieve the effect of advanced production technology, improve bioavailability, and increase the degree of dissolution and absorption

Inactive Publication Date: 2015-03-25
HEILONGJIANG ZHICHENG MEDICAL TECH
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Problems solved by technology

[0003] Traditional Chinese medicine compound preparations for the treatment of angina pectoris often use various raw medicinal materials to be crushed into fine powder (above 80 mesh) and taken after mixing. Traditional Chinese medicine pills and powders account for a considerable proportion of solid preparations. The traditional processing technology makes the drug particle size 125-180 μm, which is not conducive to the full absorption of active ingredients, and has the disadvantages of high production cost and general drug utilization.

Method used

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  • Traditional Chinese medicine compound powder for treating stenocardia and preparation method thereof

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Embodiment 1

[0020] A traditional Chinese medicine compound powder for treating angina pectoris, which is characterized in that it is composed of the following raw materials: 190-230g of sandalwood, 190-230g of cedarwood, 190-230g of chuanxiong, 90-110g of borneol, 90-110g of frankincense, and 45-55g of storax.

[0021] The optimal mass ratio of the raw materials is: 210g of sandalwood, 210g of green wood, 210g of Chuanxiong, 105g of borneol, 105g of frankincense, and 50g of storax.

[0022] The concrete steps of its preparation method are:

[0023] 1. Milling: In addition to storax and borneol, sandalwood, green wood, chuanxiong, and frankincense are ultrafinely pulverized into powders with a diameter of less than 10 μm, and made into fine powder for later use;

[0024] 2. Make borneol β-cyclodextrin inclusion compound: take 3 parts of β-cyclodextrin, add 4 times the amount of water to mix, grind well; take another 1 part of borneol, add appropriate amount of ethanol to dissolve...

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Abstract

The invention discloses traditional Chinese medicine compound powder for treating stenocardia and a preparation method thereof. The compound powder is composed of the following ingredients: sandalwood, dutchmanspipe root, ligusticum wallichii, borneol, frankincense and storax. The preparation method comprises the following steps: carrying out the powder process; preparing a Beta-cyclodextrin inclusion compound of borneol; mixing the finished product to prepare into pills. The traditional Chinese medicine pills has the effects of regulating the flow of qi, relieving depression in the chest and relieving pain, can be used for treating stenocardia and chest distress; by adopting the Beta-cyclodextrin clathrate inclusion technology on borneol, stability of the drug is increased, and the loss of effective ingredients in the storage process is reduced; by conducting superfine grinding on the other ingredients, the solution absorption degree of the orally taken preparation in the body can be improved, the bioavailability of the drug is improved, the dosage is reduced, the raw materials are saved, the efficiency is improved, and the cost is reduced.

Description

technical field [0001] The invention belongs to the field of pharmacy, and in particular relates to a traditional Chinese medicine compound powder for treating angina pectoris and a preparation method thereof. Background technique [0002] Cardiovascular disease is one of the most common and serious diseases that endanger human health (especially middle-aged and elderly people). Dyslipidemia is an important risk factor for atherosclerosis, coronary heart disease and other cardiovascular and cerebrovascular diseases. Lipid-lowering drugs can reduce these The incidence and mortality of diseases have a positive and far-reaching impact on the prevention and treatment of cardiovascular diseases. According to the statistics of IMSHealth in the United States, the global lipid-lowering drug market has reached 33.849 billion US dollars in 2008, an increase of 1.75% over the previous year, accounting for 4.38% of the global pharmaceutical market, ranking second only to antineoplastic ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/324A61K9/14A61P9/10
CPCA61K36/185A61K9/2068A61K31/045A61K36/236A61K36/264A61K36/324A61K47/6951A61K2300/00
Inventor 张昕
Owner HEILONGJIANG ZHICHENG MEDICAL TECH
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