Chitosan hemostatic gauze and preparation method thereof

A technology of hemostatic gauze and chitosan, which is applied in the field of medicine, can solve the problems of complex waste treatment process, the influence of foreign body rejection, poor antibacterial and antibacterial ability, etc., and achieve the effect of good antibacterial effect, no toxic side effects, and easy absorption

Inactive Publication Date: 2015-04-22
ANHUI JIANYUAN MEDICAL APP & INSTR EQUIP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional hemostatic gauze is generally made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affe

Method used

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Examples

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Embodiment Construction

[0020] Non-limiting examples of the present invention are as follows:

[0021] A kind of chitosan hemostatic gauze is prepared from the component raw materials of following weight (kg):

[0022] Geranium 4, Angelica dahurica 4, Panax notoginseng 1.5, Gardenia 1.5, Chitosan 5, Gelatin 10, Squalane 0.15, Polysorbate-80 0.15, Sodium alginate 3, Sodium carboxymethylcellulose 3, Hydroxyethyl Starch 1.5, auxiliary materials 1.5, water 200;

[0023] Among them, the auxiliary materials are made of raw materials with the following weights (kg):

[0024] Soy lecithin 0.8, glycerin 3, polyethylene glycol 1.5, bletilla striata superfine powder 1.5, mannitol 3, chlorhexidine gluconate 1.5, vitamin C 1.5, water 18;

[0025] Preparation method of excipients:

[0026] Add soybean lecithin into water at 60°C and stir at 1000r / min for 1 hour, then add glycerin, polyethylene glycol, superfine powder of Bletilla striata and mannitol and stir for 15 minutes under the same conditions, after cool...

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PUM

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Abstract

The invention discloses chitosan hemostatic gauze. The chitosan hemostatic gauze is characterized by being prepared from the following raw materials in parts by weight: 3-5 parts of pelargonium hortorum, 3-5 parts of dahurian angelica root, 1-2 parts of panax notoginseng, 1-2 parts of cape jasmine, 4-6 parts of chitosan, 8-12 parts of gelatin, 0.1-0.2 part of squalane, 0.1-0.2 part of polysorbate-80, 2-4 parts of sodium alginate, 2-4 parts of sodium carboxymethylcellulose, 1-2 parts of hydroxyethyl starch, 1-2 parts of auxiliary materials and 200-250 parts of water. According to the chitosan hemostatic gauze disclosed by the invention, soluble hemostatic gauze is prepared from natural high molecular materials such as chitosan and the like in a coordination mode, the soluble hemostatic gauze has good hemostatic functions and good antibacterial effects, is easy to be absorbed by a human body, is good in biocompatibility, and cannot cause toxic or side effect; by extracting and compounding natural plant effective components, the hemostatic gauze can be used for diminishing inflammation and relieving pain, and converging and removing scars; and moreover, the chitosan hemostatic gauze has slow release effects, can be used for effectively prolonging the action time, and ensures that better use effects can be achieved.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a chitosan hemostatic gauze and a preparation method thereof. Background technique [0002] With the continuous advancement of medical technology, new medical materials and related technologies have been well developed. Among them, the development and improvement of hemostatic materials are conducive to improving the problems of surgical bleeding and bleeding, which is of great significance and has become a hot research topic in the field of medicine. Traditional hemostatic gauze is generally made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to adhere to wound tissue during use, causing secondary damage. The generated waste has a complicated treatment process and is easy to pollute the environment. [0003] Soluble hemostatic gauze is a new type of hemostatic m...

Claims

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Application Information

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IPC IPC(8): A61L15/44A61L15/40A61L15/28A61L15/32
Inventor 朱来全
Owner ANHUI JIANYUAN MEDICAL APP & INSTR EQUIP
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