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Pharmaceutical composition for treating dark eye circles and preparation method and use thereof

A technology for dark circles and compositions, which can be used in drug combinations, pharmaceutical formulations, preparations for skin care, etc., and can solve problems such as affecting the image, listlessness, etc.

Inactive Publication Date: 2015-04-29
GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Deep dark circles will make people look listless and affect the image. Therefore, the development of new safe and effective external products for the treatment of dark circles has good social and economic benefits

Method used

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  • Pharmaceutical composition for treating dark eye circles and preparation method and use thereof
  • Pharmaceutical composition for treating dark eye circles and preparation method and use thereof
  • Pharmaceutical composition for treating dark eye circles and preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0106]At room temperature, take 10 kg of Baihuabaijiang, 10 kg of Liuyueqing, 10 kg of Maodongqing, 10 kg of Speranthema, 10 kg of Centella asiatica, 10 kg of Tianshan Snow Lotus, 10 kg of golden ear, 10 kg of airplane grass ( A total of 80 kilograms), soak and extract with 800 kilograms of ethanol with a volume concentration of 70%, and the soaking time is 24 hours. After filtering through the filter screen, concentrate under reduced pressure for 20 times, then put the concentrated solution on the macroporous resin, and elute with ethanol with a volume concentration of 50%, and the collected eluate contains the active ingredients required in the prescription of the present invention, that is, the drug combination.

Embodiment 2

[0108] At room temperature, take 8 kg of Baihuabaijiang, 8 kg of Liuyueqing, 8 kg of Maodongqing, 12 kg of Speranthema, 12 kg of Centella asiatica, 12 kg of Tianshan Snow Lotus, 12 kg of golden ear, and 12 kg of airplane grass ( A total of 84 kilograms), soak and extract with 1680 kilograms of ethanol with a volume concentration of 50%, and the soaking time is 24 hours. After filtering through the filter screen, concentrate under reduced pressure for 40 times, then put the concentrated solution on the macroporous resin, and elute with ethanol with a volume concentration of 40%, and the collected eluate contains the active ingredient required in the prescription of the present invention, namely the drug combination.

Embodiment 3

[0110] At room temperature, take 8 kg of Baihuabaijiang, 8 kg of Liuyueqing, 15 kg of Maodongqing, 15 kg of Speranthema, 15 kg of Centella asiatica, 15 kg of Tianshan Snow Lotus, 15 kg of golden ear, and 15 kg of airplane grass ( Totally 106 kilograms), soak and extract with 1060 kilograms of ethanol of volume concentration 80%, soaking time is 24 hours, residue is extracted with 1060 kilograms of ethanol of volume concentration 80% again and soaks for 24 hours, then the solution after soaking is combined, through 200 purpose Concentrate 25 times after filter screen filtration, then put the concentrated solution on macroporous resin, elute with ethanol with a volume concentration of 60%, and the collected eluate contains the active ingredients required in the prescription of the present invention, that is, the pharmaceutical composition.

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Abstract

The invention discloses a pharmaceutical composition for treating dark eye circles and a preparation method and use thereof. Raw materials of the pharmaceutical composition are all natural active ingredients and are nonirritant to skin. The pharmaceutical composition with a dark eye circle treating effect is prepared from patrinia villosa, strobilanthes affinis, ilex pubescens, incarrillea sinensis, centella asiatica, saussurea involucrata, carpesium divaricatum and eupatorium odoratum, wherein the weight percent of any ingredient is not higher than 30% the overall weight. The raw materials of the pharmaceutical composition disclosed by the invention are simply obtained, and the preparation method is convenient. Proved by clinical trial results, the pharmaceutical composition disclosed by the invention has a good effect on the treatment of the dark eye circles, is nonirritant and non-allergic to the skin, is easily accepted by mass consumers, and has good application prospect and market prospect.

Description

technical field [0001] The invention relates to a pharmaceutical composition and its preparation method and application, in particular to a cosmetic pharmaceutical composition with the effect of treating dark circles, its preparation method and application. Background technique [0002] The skin around the eyes is the thinnest, and the melanin activity is very strong. Coupled with aging, external stimuli and other factors, various problems are prone to occur, and the appearance of dark circles is inevitable! The so-called dark circles are when the blood flow in the veins of the eyes is too slow, the supply of red blood cells in the skin of the eyes is insufficient, and the carbon dioxide and metabolic wastes in the veins accumulate too much, forming chronic hypoxia, darker blood and formation of stagnant and dark circles around the eyes. Hyperpigmentation A bluish-blue or dark brown shade that forms around the eye. In Chinese medicine, it is called "eyeliner". Clinical man...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/47A61K36/28A61K8/97A61P17/00A61Q19/00
Inventor 王恩瀚
Owner GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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