The invention relates to a looks-improving, youth-keeping and anti-aging health care food which can strengthen human immunity function and a preparation method thereof. The health care food compounds donkey hide gelatin, polygonatum, poria cocos, cassis seed, rhizoma polygonatum, wolfberry fruit, etc. raw materials in accordance with a certain portion. The raw materials are made into oral liquid, granule or tea drinking through the preparation technique of cleaning, precise selection, processing, grinding, etc. The health care food of the invention, based on the theory of keeping health of Chinese traditional medicine, has the functions of conserving outside with inside, looks improving and youth keeping, delaying aging and strengthening the immunity function of human body. The raw materials of the invention are natural, atoxic and harmless and do not have side effects; meanwhile, the source of the raw materials is sufficient. The preparation method is scientific and reasonable, simple and easy.