The invention discloses a medicine for alleviating nervousness and taking care of sub-health. Materials of rhizome polygonati, meldar, jujube, mulberry, perilla, bergamot, citron, malt, Poria cocos, lily, lotus plumule, spine date seed are decocted according to a certain weight proportion, and then extracted so as to obtain the medicine which can be prepared into any common oral dosage form. Withthe functions of soothing the liver and resolving depression, relaxing the chest and regulating qi, nourishing the heart and calming the nerves, as well as tonifying qi and blood, the medicine is of obvious effect in treating sub-health syndromes of chest distress and dysphoria, nervousness, insecurity, insomnia, forgetfulness, inefficiency, lassitude, inappetence and the like, with rapid effect and little toxic side-effect.