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Coating for interventional catheter, preparation method thereof, and interventional catheter

一种介入导管、涂料的技术，应用在导管、涂层、医药科学等方向，能够解决介入导管表面亲水涂层牢固性不足等问题，达到突出实际应用效果、牢固亲水润滑性能、适用范围广的效果

Active Publication Date: 2016-07-06
BEIJING DEMAX MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The invention provides a coating for an interventional catheter, a preparation method thereof and an interventional catheter, which effectively solves the problem of insufficient firmness of the hydrophilic coating on the surface of the interventional catheter

Method used

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  • Coating for interventional catheter, preparation method thereof, and interventional catheter

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preparation example Construction

[0053] In addition, the present invention also provides a preparation method of a coating for an interventional catheter, comprising the following steps:

[0054] Preparation of primer: Add side carboxyl group-containing polyurethane, polyglycidyl acrylate and organic solvent into a container, stir at room temperature for 20-60 minutes to obtain primer; in the obtained primer, side carboxyl group-containing polyurethane and polyacrylic glycidyl The mass ratio of the ester is 1:(0.1-1), and the mass of the organic solvent is 80wt%-99wt% of the total mass of the primer.

[0055] Preparation of top coat: Add side carboxyl group-containing polyurethane, polymethyl vinyl ether-maleic anhydride and organic solvent into a container, stir at room temperature for 20-60 min to obtain top coat; in the obtained top coat, side carboxyl group-containing polyurethane The mass ratio of polymethyl vinyl ether-maleic anhydride is 1:(0.1-10), and the mass of the organic solvent is 80wt%-99wt% of...

Embodiment 1

[0084] S100: Add side carboxyl group-containing polyurethane PU-1, polyglycidyl acrylate sample 1 and N,N-dimethylacetamide into a container, and stir at room temperature for 30 minutes to obtain a primer. In the primer, the mass ratio of PU-1 to polyglycidyl acrylate is 1:0.1, and the mass of N,N-dimethylacetamide is 95% by weight of the total mass of the primer.

[0085] S200: adding side carboxyl group-containing polyurethane PU-1, polymethyl vinyl ether-maleic anhydride and ethyl acetate into a container, and stirring at room temperature for 30 minutes to obtain a top coat. In the top coat, the mass ratio of PU-1 to polymethyl vinyl ether-maleic anhydride is 1:8, and ethyl acetate is 90wt% of the total mass of the top coat. Among them, polymethyl vinyl ether-maleic anhydride is produced by Sigma Alrich, and its number average molecular weight is 80,000.

[0086] Apply the primer obtained in S100 to the surface of the interventional catheter, and cure at 60°C for 30 minute...

Embodiment 2

[0091] S100: Add side carboxyl group-containing polyurethane PU-2, polyglycidyl acrylate sample 1 and tetrahydrofuran into a container, and stir at room temperature for 20 minutes to obtain a primer. In the primer, the mass ratio of PU-2 to polyglycidyl acrylate is 1:0.2, and the mass of tetrahydrofuran is 80 wt% of the total mass of the primer.

[0092] S200: adding side carboxyl group-containing polyurethane PU-2, polymethyl vinyl ether-maleic anhydride and methylene chloride into a container, and stirring at room temperature for 20 minutes to obtain a top coat. In the top coat, the mass ratio of PU-2 to polymethyl vinyl ether-maleic anhydride is 1:10, and methylene chloride is 99wt% of the total mass of the top coat. Among them, polymethyl vinyl ether-maleic anhydride is produced by Sigma Alrich, and its number average molecular weight is 80,000.

[0093]Apply the primer obtained in S100 to the surface of the interventional catheter, and cure at 40°C for 60 minutes; then a...

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Abstract

The invention discloses paint for an intervention duct and a preparation method thereof, and the intervention duct. The paint comprises prime paint and top paint, wherein the prime paint contains polyacrylic acid glycidyl ester, polyurethane containing side carboxyl and an organic solvent, in the prime paint, the mass ratio of the polyurethane containing the side carboxyl to the polyacrylic acid glycidyl ester is 1: (0.1-1), and the mass of the organic solvent is 80wt%-99wt% of the total mass of the bottom paint; the top paint contains polyvinyl methyl ether-maleic anhydride, polyurethane containing side carboxyl and an organic solvent, in the top paint, the mass ratio of the polyurethane containing the side carboxyl to the polyvinyl methyl ether-maleic anhydride is 1: (0.1-10), and the mass of the organic solvents is 80wt%-99wt% of the total mass of the top paint. The intervention duct is coated with the paint disclosed by the invention, so that a coating with excellent wear resistance and hydrophilic performance can be obtained.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a coating for an intervention catheter, a preparation method of the coating, and an intervention catheter coated with the coating. Background technique [0002] Endovascular interventional diagnosis and treatment technology is widely used in clinical angiography, angioplasty, removal of intravascular thrombus or foreign body, etc. Compared with traditional medical technology, endovascular interventional diagnosis and treatment technology is not only convenient to operate, but also because of the low trauma of interventional treatment, it can reduce the pain of patients, the risk of treatment is small, and the cost of treatment is relatively low. Therefore, this technology is widely used in medicine. field has been widely promoted and used. Intravascular interventional diagnosis and treatment technology uses interventional catheters to reach distant diseased parts in the body, such...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L29/08A61L29/14A61L31/10A61L31/14
Inventor 王兴元戴华英
Owner BEIJING DEMAX MEDICAL TECH
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