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Polyhexamethylene guanidine oral spray

The technology of polyhexamethylene guanidine and polyhexamethylene guanidine hydrochloride is applied in the direction of anti-inflammatory agent, antiviral agent, antifungal agent, etc., which can solve the problems of unscientific formula, single function, poor taste, etc. Safe and reliable use, obvious effect, fast onset effect

Inactive Publication Date: 2015-05-06
卫国刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are some oral sprays on the market that add polyhexamethylene guanidine, but the formula is not scientific enough, the function is relatively single, and the taste is very bad.

Method used

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Embodiment Construction

[0019] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with specific embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, and are not intended to limit the present invention.

[0020] This specific embodiment adopts the following technical scheme: its mass ratio formula consists of: polyhexamethyleneguanidine hydrochloride 0.05%-0.5%, synergist 1%, glycerin 20%-30%, sodium saccharin 0.001%-0.5% , mint 0.05%, solubilizer 0.05%, purified water 69%-79%.

[0021] The production technology of this embodiment is:

[0022] (1) Prepare mint and solubilizer according to the above ratio and stir for 15 minutes to obtain water-soluble mint solution A;

[0023] (2) According to the above ratio, add polyhexamethyleneguanidine hydrochloride and synergist into purified water in sequence, ...

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PUM

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Abstract

The invention discloses a polyhexamethylene guanidine oral spray, and relates to the technical fields of inflammation diminishing and pain relieving in an oral cavity. The polyhexamethylene guanidine oral spray comprises the following components in percentage by mass: 0.05%-0.5% of polyhexamethylen guanidine hydrochloride, 1% of a synergist, 20%-30% of glycerinum, 0.001%-0.5% of saccharin sodium, 0.05% of mint, 0.05% of a solubilizer and 69%-79% of purified water. The production process comprises the following steps: stirring the mint and the solubilizer at the ratio for 15 minutes to obtain a water-soluble mint solution A; sequentially adding polyhexamethylen guanidine hydrochloride and the synergist to purified water at the ratio, and stirring for 5 minutes to obtain a solution B; and stirring evenly, adding the water-soluble solution A, glycerinum and saccharin sodium to the solution B at the ratio, and stirring for 30 minutes to obtain the polyhexamethylene guanidine oral spray. The polyhexamethylene guanidine oral spray is scientific and reasonable in formula, has the advantages of being fast in acting, free of thrill, free of a toxic or side effect, and free of drug resistance, has a mucosal protection effect and has the effects of diminishing inflammation and relieving pain.

Description

Technical field: [0001] The invention relates to the technical field of oral anti-inflammatory and pain-relieving, in particular to a polyhexamethyleneguanidine oral spray. Background technique: [0002] Polyhexamethyleneguanidine is a broad-spectrum antimicrobial agent whose chemical nature is a cationic polymer. Polyhexamethyleneguanidine can broad-spectrum and powerfully kill all kinds of bacteria, viruses and fungi, and has long-term antibacterial effect, which can effectively prevent secondary pollution of bacteria. Therefore, polyhexamethyleneguanidine is not only a high-efficiency disinfection It is an ideal broad-spectrum antibacterial agent. [0003] The derivatives of polyhexamethyleneguanidine include polyhexamethyleneguanidine hydrochloride, polyhexamethyleneguanidine phosphate, etc. The bactericidal mechanism of polyhexamethyleneguanidine hydrochloride is explained by relevant experts as: because its guanidine group has a high The activity makes the polymeriza...

Claims

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Application Information

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IPC IPC(8): A61K9/12A61K31/785A61K47/46A61P29/00A61P31/04A61P31/12A61P31/10A61P1/02
Inventor 卫国刚
Owner 卫国刚
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