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Traditional Chinese medicine composition for treating diabetic retinopathy and preparation method thereof

A technology of diabetic retinopathy and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of diabetic retinopathy, can solve the problems of high recurrence rate, unsatisfactory treatment effect, and inability of western medicine to effectively treat diabetic eye disease, etc., to achieve quick results, The effect of better drug treatment and improved medication compliance

Inactive Publication Date: 2015-06-10
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine cannot effectively treat diabetic eye disease, and long-term use of western medicine has many side effects. Traditional Chinese medicine has a better therapeutic effect. At present, there are many traditional Chinese medicine preparations such as Anxue Granules, Tangwang Decoction, and Paiye Decoction for diabetic retinopathy. During the treatment, it can relieve the symptoms of vitreous hemorrhage and macular edema caused by diabetes, but there are still some shortcomings such as unsatisfactory treatment effect and high recurrence rate.

Method used

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  • Traditional Chinese medicine composition for treating diabetic retinopathy and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 Chinese medicine composition of the present invention and preparation technology

[0023] The composition of the prescription is as follows:

[0024] Pseudostellaria 8kg, Chuanxiong 5kg, Scrophulariaceae 5kg, Akebia 3kg, Scutellaria baicalensis 10kg, Cimicifuga 5kg, Ophiopogon japonicus 10kg, Clematis 3kg, Poria cocos 10kg, Cuscuta 5kg, Chenpi 8kg, Agrimony 5kg, Ginger pinellia 10kg, Bletilla striata 3kg, Centella Asiatica 5kg, Habitat 3kg, Morinda officinalis 3kg, Motherwort 5kg, Honeysuckle 10kg, Eucommia 10kg, Xanthium 3kg, Wormwood 5kg, Astragalus 5kg, Polygonum multiflorum 5kg, Licorice 10kg;

[0025] Preparation method: Take the prescription amount of the above-mentioned Chinese medicinal materials and crush them into coarse powder, add 40% ethanol solution with a volume concentration of 4 times the total weight of the coarse powder, reflux extraction three times, reflux time is 5h, filter, recover ethanol from the filtrate, cool and filter , washed ...

Embodiment 2

[0026] Embodiment 2 Chinese medicine composition of the present invention and preparation technology

[0027] The composition of the prescription is as follows:

[0028] Pseudostellaria 20kg, Chuanxiong 15kg, Scrophulariaceae 15kg, Akebia 10kg, Scutellaria baicalensis 25kg, Cimicifuga 15kg, Ophiopogon japonicus 20kg, Clematis 10kg, Poria cocos 20kg, Cuscuta 15kg, Tangerine peel 20kg, Agrimony 12kg, Ginger pinellia 20kg, Bletilla striata 10kg, Centella Asiatica 15kg, Habitat 10kg, Morinda officinalis 10kg, Motherwort 12kg, Honeysuckle 15kg, Eucommia 20kg, Xanthium 10kg, Wormwood 15kg, Astragalus 15kg, Polygonum multiflorum 25kg, Licorice 20kg;

[0029] Preparation method: Take the prescription amount of the above-mentioned Chinese medicinal materials and crush them into coarse powder, add 90% ethanol solution according to the volume concentration of 5 times the total weight of the coarse powder, reflux extraction three times, the reflux time is 3h, filter, recover ethanol from ...

Embodiment 3

[0030] Embodiment 3 Chinese medicine composition of the present invention and preparation technology

[0031] The composition of the prescription is as follows:

[0032]Pseudostellaria 15kg, Chuanxiong 10kg, Scrophulariaceae 10kg, Akebia 7kg, Scutellaria baicalensis 18kg, Cimicifuga 10kg, Ophiopogon japonicus 15kg, Clematis 7kg, Poria cocos 15kg, Cuscuta 10kg, Tangerine peel 14kg, Agrimony 9kg, Ginger pinellia 15kg, Bletilla striata 7kg, Centella Asiatica 10kg, Habitat 7kg, Morinda officinalis 6kg, Motherwort 8kg, Honeysuckle 13kg, Eucommia 15kg, Xanthium 7kg, Wormwood 10kg, Astragalus 10kg, Polygonum multiflorum 20kg, Licorice 15kg;

[0033] Preparation method: Take the prescription amount of the above-mentioned Chinese medicinal materials and crush them into coarse powder, add 70% ethanol solution according to the volume concentration of 5 times the total weight of the coarse powder, reflux extraction three times, the reflux time is 4h, filter, recover ethanol from the filtr...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating diabetic retinopathy and a preparation method thereof. To overcome the defects in the prior art, the traditional Chinese medicine composition mainly comprises 8-20 parts of heterophylly falsestarwort roots, 5-15 parts of rhizoma chuanxiong, 5-15 parts of scrophulariae, 3-10 parts of caulis akebiae, 10-25 parts of radix scutellariae, 5-15 parts of rhizoma cimicifugae, 10-20 parts of radix ophiopogonis, 3-10 parts of clematis chinensis, 10-20 parts of poria cocos, 5-15 parts of semen cuscutae, 8-20 parts of tangerine peel, 5-12 parts of agrimonia pilosa ledeb, 10-20 parts of ginger processed pinellia, 3-10 parts of bletilla striata, 5-15 parts of centella asiatica, 3-10 parts of dried radix rehmanniae, 3-10 parts of morinda officinalis, 5-12 parts of herba leonuri, 10-15 parts of honey suckle, 10-20 parts of eucommia ulmoides, 3-10 parts of fructus xanthii, 5-15 parts of wormwood, 5-15 parts of radix astragali, 5-25 parts of polygonum multiflorum and 10-20 parts of radix glycyrrhizae. Pharmacology experiments and clinical experiments prove that the traditional Chinese medicine composition has a remarkable effect of treating the diabetic retinopathy and high medical popularization value.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating diabetic retinopathy and a preparation method thereof. Background technique [0002] Diabetic retinopathy is the consequence of diabetic microangiopathy. According to relevant statistics, the longer the duration of diabetes, the greater the rate of retinopathy in patients. According to domestic reports, 38%-39% of the disease course is less than 5 years; the incidence rate of 5-10 years is 50%-56.7%; the incidence rate of more than 10 years increases to 70%-90%; the average prevalence rate is 50 %-63%. Due to the damage of the retinal capillary wall caused by diabetes, combined with the hypercoagulable state of blood, it is easy to cause thrombus and blood stasis, and even rupture of blood vessels. Diabetic retinopathy is currently the leading cause of vision loss and blindness. In the early stage of...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P3/10A61P9/10
Inventor 不公告发明人
Owner QINGDAO YUNTIAN BIOTECH
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