Quality detection method for qi-moving Tannikaer capsule

A quality inspection method and gas-activating tennecal technology, applied in the field of chemical analysis, can solve the problems of cumbersome operation, long time consumption, unfavorable environmental protection, etc., and achieve the effect of ensuring drug safety.

Active Publication Date: 2015-07-15
XINJIANG QUANAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In this way, on the one hand, the operation is cumbersome and time-consuming; on the other hand, there are many three wastes produced, which is not conducive to environmental protection

Method used

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  • Quality detection method for qi-moving Tannikaer capsule
  • Quality detection method for qi-moving Tannikaer capsule
  • Quality detection method for qi-moving Tannikaer capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0186] Example 1 Preparation of Xingqi Tennical Capsules

[0187] API prescription:

[0188] Aloe Vera 230.4g, Pepper 172.8g, Hyacinth 28.8g, Borax 36.0g.

[0189] Prepared by:

[0190] The above four flavors are crushed into fine powder, sieved, mixed evenly, packed into capsules, 0.3g per capsule, 1000 capsules in total.

Embodiment 2

[0191] Example 2 Quantitative determination of aloin and piperine by high performance liquid chromatography

[0192] Determined with reference to the high-performance liquid phase method recorded in Appendix VID of the Chinese Pharmacopoeia 2010 edition.

[0193] High-performance liquid chromatography: Agilent 1100; data processor: Agilent 1100 ChemStation; ultraviolet detector: VWD G1314A.

[0194] Chromatographic conditions and system suitability

[0195] Column: AKZONOBEL Kromasil 100-5C 18 , 4.6×250mm;

[0196] Column temperature: 30°C;

[0197] Mobile phase: Acetonitrile was used as mobile phase A, water was used as mobile phase B, gradient elution, and the elution program was shown in Table 1;

[0198] Flow rate: 1.0ml / min;

[0199] Detection wavelength: 350nm;

[0200] The number of theoretical plates calculated based on the aloin peak should not be less than 5000.

[0201] Preparation of Reference Substance Solution Take an appropriate amount of aloin reference ...

Embodiment 3

[0205] Example 3 TLC Qualitative Identification of Borax

[0206] Preparation of the test solution: take 1.5 g of the contents of the three batches of capsules prepared according to Example 1, put them in a crucible, heat slowly until completely charred, let cool to room temperature, place the carbonized matter in a mortar, grind finely, transfer To a centrifuge test tube, add 10ml of water, power 250W, ultrasonic treatment at a frequency of 35kHz for 10min, centrifuge at a speed of 6000 rpm for 10min, filter, concentrate the filtrate to dryness, add 1ml of methanol to the residue to dissolve, add 1 drop of sulfuric acid, and let stand. Get supernatant as need testing solution;

[0207] The Xingqi Tannecal Capsules with batch numbers 20111001, 20111002 and 20111003 were prepared respectively according to the above-mentioned method.

[0208] Preparation of reference solution: Take another 50 mg of borax, add 2 ml of methanol, sonicate to dissolve, add 1 drop of sulfuric acid...

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Abstract

The invention provides a quality detection method for a qi-moving Tannikaer capsule which is originated from Uygur traditional medicine and used for treating abdominal distension and constipation. The quality detection method comprises a step of simultaneously detecting the contents of barbaloin and piperine by using high performance liquid chromatography and gradient elution and another step of qualitatively discriminating borax, aloe and / or pepper by using thin-layer chromatography. The quality detection method provided by the invention is convenient, labor-saving and time-saving to operate and can comprehensively reflect the quality of the qi-moving Tannikaer capsule, thereby guaranteeing medication safety of patients.

Description

technical field [0001] The invention belongs to the field of chemical analysis, and in particular relates to a quality detection method of a qi-promoting Tannical medicinal composition for treating anorexia, abdominal distension and constipation. Background technique [0002] In Xinjiang, the ethnic medicines mainly of Uyghur, Kazak and Mongolian have a long history and definite curative effect. In particular, Uighur medicine has formed a unique theoretical system in the long-term historical accumulation, research and development, and application. It is an important part of the traditional medicine of the motherland. etc. played a very important role. [0003] "Promoting Qi Tennical Capsule" is a preparation with regional characteristics in Xinjiang. The raw materials of the capsule are composed of aloe vera, pepper, borax and angelica. ,constipate. Long-term clinical application shows that the drug has good curative effect and quick effect. However, due to the limitatio...

Claims

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Application Information

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IPC IPC(8): G01N30/02G01N30/90
Inventor彭一峰杨应梅周寒利蒋惠娟王峄尹洪强
OwnerXINJIANG QUANAN PHARMA