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Medicine composition for treating rheumatoid arthritis and preparation method thereof

A rheumatoid and arthritis technology, applied in the field of drug combination and its preparation, can solve the problems of joint injury, autoimmunity and infection, and slow down the deterioration of the disease, and achieve the goal of reducing economic burden, moderate price, and remarkable clinical curative effect Effect

Inactive Publication Date: 2015-08-12
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Controlling rheumatoid drugs can alleviate, delay or stop the deterioration of the disease for a long time, that is, prevent the bone and joint from secondary inflammation to uncontrollable damage, but generally cause some side effects, such as liver, bone marrow and kidney toxicity, pneumonia , skin sensitivity, autoimmunity and infection
Anti-inflammatory and analgesic drugs can reduce pain and improve stiffness, but they cannot prevent joint damage or slow down the progression of the disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Proportionally take 5 parts of Flying Dragon's Palm Blood, 10 parts of Big Diamond, 1 part of Star Anise Maple, 10 parts of Spatholobus Spatholobus, 5 parts of Liangmianzhen, 10 parts of Qingfengteng, 10 parts of Nine Dragon Vine, 10 parts of Five Fingers Peach Root, add 10 parts Double the water, heat and reflux and decoct two to three times, each time for 1 hour, filter, combine the filtrates, concentrate under reduced pressure at 60-70°C to a clear paste with a relative density of 1.15-1.20 at 55°C, add 90% ethanol to make the alcohol content 60%, stand at room temperature for 12 hours, filter, recover ethanol, concentrate to a thick paste with a relative density of 1.30-1.35, add appropriate amount of auxiliary materials, mix well, and make granules. How to use: 2-3 times a day, 2-3 grams each time. Thirty days a course of treatment.

Embodiment 2

[0039] Proportionally take 10 parts of Feilongzhang blood, 15 parts of Dazuan, 6 parts of star anise, 15 parts of Caulis Spatholobus, 10 parts of Liangmianzhen, 15 parts of Qingfengteng, 15 parts of Jiulongteng, 15 parts of Wuzhi hair peach root, add 10 parts Double the water, heat and reflux and decoct two to three times, each time for 1 hour, filter, combine the filtrates, concentrate under reduced pressure at 60-70°C to a clear paste with a relative density of 1.15-1.20 at 55°C, add 90% ethanol to make the alcohol content 60%, stand at room temperature for 12 hours, filter, recover ethanol, concentrate to a thick paste with a relative density of 1.30-1.35, add appropriate amount of auxiliary materials, mix, granulate, pack into capsules, and obtain capsules. How to use: 2-3 times a day, 2-3 grams each time. Thirty days a course of treatment.

Embodiment 3

[0041] Proportionally take 15 parts of Feilongzhang blood, 20 parts of Dazuan, 11 parts of star anise, 20 parts of Caulis Spatholobus, 15 parts of Liangmianzhen, 20 parts of Qingfengteng, 20 parts of Jiulongteng, 20 parts of Wuzhi hair peach root, add 10 parts Double the water, heat and reflux and decoct two to three times, each time for 1 hour, filter, combine the filtrates, concentrate under reduced pressure at 60-70°C to a clear paste with a relative density of 1.15-1.20 at 55°C, add 90% ethanol to make the alcohol content 60%, stand at room temperature for 12 hours, filter, recover ethanol, concentrate to a thick paste with a relative density of 1.30-1.35, add appropriate amount of auxiliary materials, mix well, and compress to obtain tablets. How to use: 2-3 times a day, 2-3 grams each time. Thirty days a course of treatment.

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PUM

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Abstract

The invention discloses a medicine composition for treating rheumatoid arthritis and a preparation method thereof, wherein the medicine composition is prepared from following raw materials, by weight: 5-15 parts of asiatic toddalia roots, 10-20 parts of kadsura coccinea, 1-11 parts of alangium chinense, 10-20 parts of kadsura interior, 5-15 parts of radix zanthoxyli, 10-20 parts of caulis sinomenii, 10-20 parts of bauhinia championii and 10-20 parts of rhizome radix fici simplicissimae. In the invention, a Zhuang nationality special formula called "Zhuang medicine Longzuan arthromyodynia freeing formula" is creatively researched to prepare a novel medicinal preparation called "Zhuang medicine Longzuan arthromyodynia freeing granules", or capsules and tablets which are convenient to take and carry, is quick in absorption, and is high in bioavailability. The preparation process is simple, is significant in effect and is less in side effect.

Description

technical field [0001] The invention relates to a medicine combination and a preparation method thereof, in particular to a medicine combination for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (English: Rheumatoid arthritis, RA for short) is a long-term chronic inflammation caused by an autoimmune disorder that causes the immune system to attack the joints. This inflammation can deform the joints to the point of disabling them, with partial loss of mobility due to joint pain and wear. The condition also affects other extra-articular tissues systemically, including the skin, blood vessels, heart, lungs, and muscles. [0003] The pharmacological treatment of rheumatoid arthritis can be divided into control rheumatoid drugs, anti-inflammatory drugs and anti-pathological drugs. Controlling rheumatoid drugs can alleviate, delay or stop the deterioration of the disease for a long time, that is, prevent the bo...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P19/02A61P29/00
Inventor 庞宇舟农毅清蒋祖玲罗宇东陈洪涛刘源焕谭安蔷蒋林
Owner GUANGXI UNIV OF CHINESE MEDICINE
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