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Medicinal composition for treating ischemic stroke

An ischemic stroke and composition technology, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of staying and unsatisfactory treatment effect, and achieve the prevention of hemiplegia, the reduction of hemiplegia rate and mortality, and the reduction of toxic and side effects. Effect

Active Publication Date: 2015-08-12
SICHUAN PROVINCIAL PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the clinical treatment of ischemic stroke basically stays in dehydration, thrombolysis, prevention and treatment of infection, and symptomatic treatment, but the treatment effect is far from ideal

Method used

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  • Medicinal composition for treating ischemic stroke
  • Medicinal composition for treating ischemic stroke
  • Medicinal composition for treating ischemic stroke

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-11

[0029] Take Astragalus, Angelica, Chuanhonghua, Chishao, Chuanxiong, Gentiana, Salvia, Cassia, Unteng, Eucommia, Licorice, Panax notoginseng, Earthworm, Gastrodia, Scorpion, and Centipede, and make proportions according to the dosages shown in Table A Mix and decoct 3 times, use 300ml of water for the first time, 150ml of water for the second time, 150ml of water for the third time, combine the decoction, and concentrate the decoction to 200ml in Example 1-6 to obtain the Chinese medicine composition soup for treating stroke Concentrate to dryness after the combined decoction of embodiment 7-9, obtain mixed extract, add suitable auxiliary material, press into tablet; The decoction of embodiment 10-11 is combined and concentrated to dry, mix with appropriate amount of auxiliary material, make capsule .

[0030] Table A Ratio of dosage of raw medicinal materials

[0031]

Embodiment 12

[0033] Take astragalus 30g, angelica 10g, Chuanhonghua 10g, red spoon 15g, Chuanxiong 10g, Gentiana 30g, salvia miltiorrhiza 15g, cassia seed 30g (stir-fried), 30g Eucommia ulmoides 30g, 10g licorice, 15g Panax notoginseng 20g, Gastrodia elata 30g, scorpion 10g, and 5 centipedes. Add 600ml of water to decoct, repeat the decoction twice, combine the decoction, concentrate to 200ml, and obtain the Chinese medicine decoction for treating ischemic stroke.

Embodiment 13

[0035]Take astragalus 32g, angelica 11g, Sichuan safflower 11g, red spoon 17g, Chuanxiong 9g, Gentiana 28g, salvia miltiorrhiza 20g, cassia seed 28g (fried), 32g Eucommia ulmoides 30g, licorice 8g, add 400ml of water to decoct, repeat the decoction three times, combine the decoction, concentrate to 200ml, Get a liquid dose. Take 15g of Panax notoginseng, 23g of Dilongpi, 22g of Gastrodia elata, 10g of scorpion, and 4 centipedes, dry it, grind it into powder, add it to the above-mentioned liquid preparation, and mix well to obtain a traditional Chinese medicine oral liquid for treating ischemic stroke.

[0036] Typical cases

[0037] Qihong Naosu Decoction has treated more than 300 cases of "stroke hemiplegia" caused by ischemic cerebral apoplexy in clinical practice, with a total effective rate of more than 90. Here are two typical cases in October 2014 as follows:

[0038] 1. Yang, female, 68 years old, address: a community in Rong County, Zigong City, Sichuan Province

[0...

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Abstract

The invention discloses a medicinal composition for treating ischemic stroke. The medicinal composition comprises one or more of Radix Astragali, Chinese angelica, Eucommia ulmoides, Panax Notoginseng, radix paeoniae rubra, Ligusticum wallichii, Salvia miltiorrhiza and safflower in Sichuan, and one or more of Gambir Plant, rhizoma gastrodiae, cassia seed, Gentiana macrophylla, lumbricus, scorpion and centipede. The traditional Chinese medicinal composition can improve ischemic damaged brain tissue structure, reduces intercellular substance oedema, substantially reduces the level of TNF-alpha and ICAM-1, has an anti-cerebral ischemia damage effect, has the efficacies of blood stasis removing, tissue regeneration promoting, endogenous wind calming and vein relaxing, can substantially reduce the hemiplegia rate and mortality of thrombus hemiplegia, and also can substantially improve acute blood stasis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating ischemic stroke. Background technique [0002] Ischemic stroke refers to hemiplegia and disturbance of consciousness caused by cerebral infarction and cerebral artery blockage on the basis of cerebral thrombosis or cerebral thrombosis. It is a common clinical major disease. There are about 1.5 million new patients and about 1 million deaths in my country every year. It has the characteristics of high morbidity, high disability rate, and high recurrence rate. About 50% of the patients lost their lives due to severe disabilities (paralysis, dementia, language barriers, etc.). The ability to live and work has caused heavy family and social burdens. [0003] At present, the clinical treatment of ischemic stroke basically stays in dehydration, thrombolysis, prevention and treatment of infection, and symptomatic treatm...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K36/74A61P9/10A61K35/646A61K35/648A61K35/62
Inventor 廖菁范子煊
Owner SICHUAN PROVINCIAL PEOPLES HOSPITAL
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