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Natural pharmaceutical composition capable of preventing and treating alcoholic liver injury and preparation method
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A technology of alcoholic liver injury and natural medicine, which is applied in the field of medicine to achieve the effect of promoting scavenging, eliminating excessive free radicals, and hindering the formation of lipid peroxide
Active Publication Date: 2015-09-16
JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
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Problems solved by technology
So far, there is no ideal drug to effectively prevent and treat the occurrence and development of liver diseases in clinical practice.
Method used
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Embodiment 1
[0049] Embodiment 1, Preparation of total triterpene acids from loquat leaves
[0050] (1) Loquat leaves 5kg, decocted with 10 times the amount of water to extract twice, each time for 2 hours, filtered, combined the filtrate for later use; dregs were extracted twice with 6 times the amount of 80% ethanol, each time for 2 hours, filtered, Combine the filtrates, add 400g of medicinal activated carbon, stir, filter, and recover ethanol from the filtrate, concentrate, filter, and dry the filter cake to obtain the total triterpene acids of loquat leaves.
Embodiment 2
[0051] Example 2 , Preparation of total flavonoids from loquat leaves
[0052] (2) Concentrate the water extract of loquat leaves to 7500ml, pass through the pre-treated AB-8 macroporous resin column, elute with deionized water for 4 times the column volume, discard the eluent, and then wash with 60% ethanol Remove 5 times the column volume, collect the eluate, recover ethanol, and dry to obtain the total flavonoids of loquat leaves.
Embodiment 3
[0053] Example 3 , Preparation of total flavonoids from loquat leaves 5 kg of grape leaves, reflux extraction with 8 times the amount of 60% ethanol for 2 times, each time for 3 hours, filtered, the filtrate recovered ethanol, concentrated to 7500ml, passed through the pre-treated AB-8 macroporous resin column, first used to remove Elute with deionized water for 5 times the column volume, discard the eluent, then elute with 10% ethanol for 3 times the column volume, discard the eluent, and then elute with 65% ethanol for 4 times the column volume, collect the eluate, Recover the ethanol and dry it to obtain the total flavonoids of the Serpentis japonicus.
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Abstract
The invention relates to a natural pharmaceutical composition capable of alcoholism prevention and liver protection. The composition is composed of loquat leaf total triterpenoid acid, loquat leaf total flavonoids, Ampelopsis grossedentata total flavonoids and a stigma maydis extract. The invention also relates to applications in preparing health foods capable of preventing and treating acute and chronic alcoholic liver injuries and health foods or drinks capable of treating non-alcoholic fatty liver diseases by the composition. Components of the composition of the invention generate good collaboration, treatment effects are obvious, raw materials are easy to obtain, the cost is relatively low, and practicability is strong.
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