Preparation technology of 2-methyl-5-trimethylsiloxyfuran

Abstract

The invention relates to the field of production of chemical engineering reagents, and especially relates to a preparation technology of 2-methyl-5-trimethylsiloxyfuran. The preparation chemical equation of 2-methyl-5-trimethylsiloxyfuran is shown in the specification, and the molecular formula of the above obtained product is also shown in the specification. A tetrahydrofuran and n-heptane composite solvent is used in the preparation technology, so the preparation technology has the advantages of no generation of poisonous or harmful substances, green and environmentally-friendly production process, high yield, enterprises' production cost reduction, and great improvement of the enterprises' economic benefits.

Description

technical field

[0001] The invention relates to the field of production and preparation of chemical reagents, in particular to a preparation process of 2-methyl-5-trimethylsilyloxyfuran. Background technique

[0002] Diels-Alder reaction (Diels-Alder), the reaction of conjugated diene and olefin to form a six-membered ring is an important organic synthesis reaction, and it is also one of the commonly used reactions in modern drug synthesis. Through this reaction, Cyclic compound molecules that are difficult to prepare by other methods can be prepared, and the reaction formula is:

[0003] , the usual conjugated dienes undergo Diels-Alder reaction, the reaction conditions are relatively strict and the reaction is reversible, so the yield is limited.

[0004] When the Diels-Alder reaction is carried out through the conjugated diene substituted by alkylsiloxy group, the reaction is usually easy to carry out, and the reaction is irreversible, which greatly improves the appli...