Traditional Chinese medicine compound external-application preparation for treating cicatrix and preparation method and application thereof
A technology for external preparations and compound recipes, which is applied in the field of traditional Chinese medicine compound external preparations and their preparation, can solve the problems of difficult infiltration of compound effect components, difficult to achieve therapeutic concentration, difficult to achieve clinical effects, etc., and achieve good economic benefits and social benefits. Benefit, significant efficacy and high product stability
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Embodiment 1
[0026] Embodiment 1: Preparation of effective part extract
[0027] (1) Grind 50g of Chuanshanlong, 50g of saponins, 20g of Wulingzhi, and 20g of Chinese gallnut into 20-60 mesh powder, add 5 times the amount of 85% ethanol, soak for 2 hours, slowly separate the extract, and extract for 3 ~5 times, the extracts were combined, concentrated under reduced pressure at low temperature and ethanol was recovered to obtain the effective fraction A for future use.
[0028] (2) Take 20g of Rhizoma Chuanxiong and 20g of Angelica sinensis and grind them into 40-60 mesh powder, CO 2 Supercritical extraction to obtain the effective fraction B for later use.
[0029] (3) Combine the effective parts A and B to obtain the extract of the effective parts of the Chinese medicine compound.
Embodiment 2
[0030] Embodiment 2: Preparation of effective part extract
[0031] (1) Grind 60g of Chuanshanlong, 60g of saponins, 50g of wulingzhi, and 50g of gallnut into 20-60 mesh powder, add 5 times the amount of 85% ethanol, soak for 2 hours, slowly separate the extract, and extract for 3 ~5 times, the extracts were combined, concentrated under reduced pressure at low temperature and ethanol was recovered to obtain the effective fraction A for future use.
[0032] (2) Take 50g of Rhizoma Chuanxiong and 50g of Angelica sinensis and grind them into 40-60 mesh powder, CO 2 Supercritical extraction to obtain the effective fraction B for later use.
[0033] (3) Combine the effective parts A and B to obtain the extract of the effective parts of the Chinese medicine compound.
Embodiment 3
[0034] Embodiment 3: Preparation of effective part extract
[0035] (1) Grind 10g of pangolin, 10g of saponins, 10g of wulingzhi, and 10g of gallnut into 20-60 mesh powder, add 5 times the amount of 85% ethanol, soak for 2 hours, slowly separate the extract, and extract for 3 ~5 times, the extracts were combined, concentrated under reduced pressure at low temperature and ethanol was recovered to obtain the effective fraction A for future use.
[0036] (2) Take 10g of Rhizoma Chuanxiong and 10g of Angelica sinensis and crush them into 40-60 mesh powder, soak in 200mL of petroleum ether (60°C-90°C) for 3 hours, filter, extract the dregs three times in the same way, and combine the petroleum ether extract , Recover petroleum ether under reduced pressure below 40°C to obtain effective fraction B for future use.
[0037] (3) Combine the effective parts A and B to obtain the extract of the effective parts of the Chinese medicine compound.
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