A synthetic patch against reflux esophagitis with radiostimulation

A reflux esophagitis, radio technology, applied in the direction of electrotherapy, medical science, prosthesis, etc., can solve the problems of life-threatening, massive bleeding, and inability to completely correct esophageal reflux, etc., to avoid dysphagia and have obvious effects Effect

Active Publication Date: 2017-04-19
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] However, this method still has the following disadvantages: 1. The mechanism of esophageal reflux includes relaxation of the lower esophageal sphincter and hiatal hernia. Electrical stimulation only solves the problem of relaxation of the esophageal sphincter. For patients with hiatal hernia, this method Still can not completely correct esophageal reflux; 2. Most of the pulse generators buried under the skin are powered by lithium batteries, and the battery life is mostly determined by the implementation time, frequency and related parameters of electrical stimulation. 3. The lower esophagus is constantly wriggling during swallowing, which may cause the electrode to loosen. Once the electrode falls off and touches other organs or blood vessels, it will cause organ damage and massive bleeding under current stimulation, endangering the patient's life

Method used

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  • A synthetic patch against reflux esophagitis with radiostimulation

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] like figure 1 A synthetic patch for anti-reflux esophagitis with radio stimulation function is shown, including upper layer 1, lower layer 2 and implantable radio stimulation device 3, the upper layer 1 and lower layer 2 are made of shape memory Material composition, wherein the upper layer 1 is a polytetrafluoroethylene layer, and the lower layer 2 is an expanded polytetrafluoroethylene layer. The upper layer 1 is a curved mesh rectangular sheet with an outer convex surface, the lower layer 2 is a curved mesh rectangular sheet with an inner concave surface, the side of the upper layer 1 opposite to the outer convex surface corresponds to the diaphragm in the human body, and the side of the lower layer 2 opposite to the inner concave surface is The anti-adhesion surface corresponds to the gastrointestinal viscera of the human body.

[0040] One side of the upper layer 1 and one side of the long side of the lower layer 2 are respectively provided with a circular notch, ...

Embodiment 2

[0047] The rest are the same as in Example 1, and the synthetic patch for anti-reflux esophagitis with radio stimulation function includes an upper layer 1, a lower layer 2 and an implantable radio stimulation device 3, and the upper layer 1 and the lower layer 2 are respectively composed of Composed of materials with shape memory properties, the side of the upper layer 1 corresponding to the outer convex surface corresponds to the inner diaphragm of the human body, and the side of the lower layer 2 opposite to the inner concave surface is an anti-adhesion surface, corresponding to the gastrointestinal viscera of the human body, one side of the upper layer 1 and the lower layer 2 One side of each side is respectively provided with a circular notch, the notch angle of the circular notch is 350°, the edge part of the outer convex surface of the upper layer 1 is connected to the edge part of the inner concave surface of the lower layer 2 and the edges of the two circular notches ar...

Embodiment 3

[0049] The rest are the same as in Example 1, and the circular recess on the outer convex surface of the lower layer 2 of the synthetic patch for anti-reflux esophagitis with radio stimulation function is 180°symmetrically provided with two groups of circular bases 4, and the upper layer 1 A notch 5 is opened at a position corresponding to the circular base 4 . The implantable radio stimulation device 3 includes a wireless energy receiving coil 31, a pulse generator 32 and four stimulating electrode sheets 33. The outer edge of the conductive layer of the stimulating electrode sheet 33 is connected to the notch 5 of the upper layer 1, and the conductive layer is correspondingly connected to the diaphragm. The insulating layers of the four stimulating electrode sheets 33 are respectively embedded in the four circular bases 4 of the lower layer 2 .

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Abstract

The invention relates to the technical field of tissue engineering, in particular to a synthesized patch with a wireless stimulation function and used for resisting reflux esophagitis. The synthesized patch comprises an upper layer, a lower layer and an implant type wireless stimulating device and is characterized in that one side of each of the upper layer and the lower layer is provided with a circular notch, the angle of each circular notch is 270 degrees, the edge part of the upper layer is connected with the edge part of the lower layer to allow the two circular notches to be connected correspondingly, sealed space is formed between the upper layer and the lower layer, and the implant type wireless stimulating device is disposed in the sealed space; the upper layer and the lower layer are made of materials with the shape memory feature, the upper layer is a teflon layer, and the lower layer is an expanded teflon layer. The synthesized patch has the advantages that the synthesized patch can be used to repair expanded esophageal hiatus, the lower esophageal sphincter is stimulated through the wireless stimulating device, the two major causes, namely hiatus hernia and lower esophageal sphincter relaxation, of the reflux esophagitis are treated effectively, and an evident effect is achieved.

Description

technical field [0001] The invention relates to the technical field of tissue engineering, in particular to a synthetic patch for anti-reflux esophagitis with radio stimulation function. Background technique [0002] The etiology of gastroesophageal reflux disease includes contraction dysfunction of the lower esophageal sphincter and hiatal hernia caused by excessive esophageal hiatus. It is a common upper gastrointestinal functional disease caused by repeated acid reflux in the esophagus. 8.8% to 27.8%, although the prevalence of gastroesophageal reflux disease in East Asia is relatively low (2.5% to 7.8%), it is still on the rise. [0003] At present, the classic anti-reflux operation is laparoscopic fundoplication + esophageal hiatus reconstruction, which effectively relieves symptoms by building a wrap around the gastroesophageal junction and strengthening the anti-reflux barrier. This anti-reflux surgery can solve the safety hazards of long-term acid suppression therap...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/02A61N1/372
Inventor 王斌裘年存仇明刘妙娥
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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