Fluorescent screening system

A fluorescence screening and filter technology, applied in the field of fluorescence imaging, can solve the problems of inconvenient filter wheel, inconvenient integration of experimental imaging, etc., and achieve the effect of good user experience and low price

Inactive Publication Date: 2016-03-23
SHENZHEN INST OF ADVANCED TECH
View PDF7 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this technical solution is inconvenient to control the conversion of the filter wheel, and it is not convenient for the integration of experimental imaging

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fluorescent screening system
  • Fluorescent screening system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0025] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0026] The working principle of this technical solution: this technical solution uses an LED white light source as the excitation light of fluorescent substances. Its advantage is that it has a wide continuous wavelength, covering the visible light band. Therefore, the switching of excitation lights with different wavelengths can be realized by using different filters. Secondly, in order to achieve fast switching between excitation and detection bands, the sy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a fluorescent screening system including a white light source exciter, a first light filter piece set, a second light filter piece set, a CCD camera and a lens. The white light source exciter emits a white light source which is then transported to the first light filter piece set. Both the first light filter piece set and the second light filter piece set respectively includes a plurality of different band-pass light filter pieces. Each band-pass light filter piece allows the light source signals in corresponding wavebands to pass while light source signals in other wavebands are filtered away. Under control of a light filter wheel, the first light filter piece set selects one light filter piece according to screening demand of fluorescent proteins in different wavelengths. The white light source, when being filtered through the light filter piece, selects excited light in required wavelength. The selected excited light then is transported to a sample to excite a fluorescent signal. The second light filter piece set selects one light filter piece under control of the light filter wheel, so that the fluorescent signal can pass through the light filter piece in the second light filter piece set to remove stray light signals. The fluorescent signal finally is collected by means of the lens to complete fluorescent imaging with the CCD camera.

Description

technical field [0001] The invention relates to the technical field of fluorescence imaging, in particular to a fluorescence screening system. Background technique [0002] Since the green fluorescent protein gene was cloned from jellyfish in 1992, new fluorescent proteins have been cloned from many marine biological species, and are widely used in the research of biomolecules, molecular interactions, cells, etc., which can be more helpful It is for us to reveal the rules and nature of the activities of these molecules or cells. This has also led to the development of fluorescent protein screening. Fluorescent screening equipment is required in the process of screening fluorescent proteins, but today's microscopy techniques are not suitable for growth in petri dishes due to their small imaging range and short focal length. Selection of clones. Although the small animal fluorescence in vivo imager in the fluorescence imaging system can image the monoclonal flat panel, the p...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64G01N21/01G01N21/84
CPCG01N21/64G01N21/01G01N21/6486G01N21/84
Inventor 储军王慧娜陈龙超林日强郭育奇张楚秋
Owner SHENZHEN INST OF ADVANCED TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap