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Medicine composition, preparation thereof and preparation method and application of preparation

A technology for a composition and a traditional Chinese medicine preparation, applied in the field of pharmaceutical compositions, can solve the problems of physical burden of cancer, incurability, etc., and achieve the effects of drug safety, controllable quality, and scientific and stable process

Inactive Publication Date: 2016-03-30
LIAONING NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment of cancer, whether it is chemotherapy, surgery or radiotherapy, is a great burden on the body, and after malignant metastasis occurs, it is difficult to completely cure it no matter what method is used

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0032] In the preparation method of the above-mentioned traditional Chinese medicine composition for treating tumors, the ethanol extraction conditions: the amount of ethanol is 6-10 times (w / v) of the original medicinal material, the ethanol concentration is 50-90%, and the extraction time is 0.5-3 hours, the number of extractions is 1 to 3 times. The concentration density is: 1.05~1.15 (20°C), and the drying method is: spray drying or drying under reduced pressure. The conditions of vacuum drying are: temperature 50~90℃, pressure -0.08MPa, drying time 24~72 hours.

[0033] In the preparation method of the above-mentioned traditional Chinese medicine composition for treating tumors, the water extraction conditions: the amount of water is 6-12 times (w / v) of the original medicinal material, the extraction time is 1-3 hours, and the extraction times are 1-3 Second-rate. The concentration density is: 1.05~1.2 (20°C), and the drying method is: normal pressure drying or reduced ...

Embodiment 1

[0039] prescription

[0040] Knotweed leaves 1500g

[0041] Hedyotis diffusa 500g

[0042] Ginseng 100g

[0043] Honeysuckle 200g

[0044] Frankincense 200g

[0045] Myrrh 200g

[0046] Licorice 100g

[0047] Preparation of traditional Chinese medicine preparations

[0048] (1) Preparation of alcohol extract: Weigh the prescribed amount of frankincense and myrrh, add 10 times the amount of 80% ethanol (w / v), and reflux extraction twice, each time for 2 hours. Combine the ethanol extracts, recover ethanol, concentrate the extracts to a thick paste with a density of 1.05 (20°C), and concentrate under reduced pressure for 48 hours at 60°C and a pressure of -0.08MPa to obtain an alcohol extract.

[0049] (2) Preparation of water extract: take the dregs of frankincense and myrrh, combine them with leaves of Polygonum cuspidatum, Hedyotis diffusa, Ginseng, honeysuckle, and licorice, add 12 times the amount of water (w / v), heat and extract twice , filtered for 3 hours each time...

Embodiment 2

[0052] prescription

[0053] Knotweed leaves 1000g

[0054] Hedyotis diffusa 200g

[0055] Ginseng 500g

[0056] Honeysuckle 250g

[0057] Frankincense 600g

[0058] Myrrh 600g

[0059] Licorice 300g

[0060] Preparation of traditional Chinese medicine preparations

[0061] (1) Preparation of alcohol extract: Weigh the prescribed amount of frankincense and myrrh, add 9 times the amount of 90% ethanol (w / v), and reflux extraction for 3 times, each time for 1.5 hours. Combine the ethanol extracts, recover ethanol, and concentrate the extracts to a thick paste with a density of 1.10 (20°C), and concentrate under reduced pressure for 40 hours at 80°C and a pressure of -0.08MPa to obtain an alcohol extract.

[0062] (2) Preparation of water extract: Take frankincense and myrrh dregs, combine with Polygonum cuspidatum leaves, Hedyotis diffusa, Ginseng, Honeysuckle, and Licorice, add 12 times the amount of water (w / v), heat and extract 3 times , filtered for 1.5 hours each ti...

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Abstract

The invention discloses a medicine composition, and a traditional Chinese medicine preparation using the medicine composition. A Chinese herbal compound is prepared with polygonum cuspidatum leaves as sovereign drugs, spreading hedyotis herb and ginseng as ministerial drugs, honeysuckle, olibanum and myrrh as adjuvant drugs and liquorice as conductant drugs, and has the functions of eliminating stagnation to relieve pain, tonifying qi and consolidating body resistance, reducing swelling and promoting tissue regeneration, and clearing away heat and toxic materials. The components resist tumors together, and the treatment aims of treating both symptoms and root causes and being safe and effective are achieved. Great treatment significance in the improvement of tumor treatment and human body functions is achieved. The production process is optimized and screened, the process is scientific and stable, and quality can be controlled. It is proved through the systemic pharma-toxicology research that the traditional Chinese medicine has an obvious anti-tumor effect, can restrain growth of tumors and can improve functions of human bodies. The traditional Chinese medicine composition is free of obvious toxic and side effects and is safe to take. The Chinese herbal medicine compound preparation capable of effectively treating tumors is obtained.

Description

technical field [0001] The invention relates to a pharmaceutical composition, a preparation prepared from the pharmaceutical composition, a preparation method of the preparation, and an application of the pharmaceutical composition in preparing antitumor drugs. Background technique [0002] Cancer is a global public health problem. In the past three decades, the incidence of cancer in the world has been increasing at an average annual rate of 3-5%, and cancer has become the number one cause of death for human beings. In 2000, there were 10.4 million new cases of cancer in the world, 6.5 million deaths, and 25 million surviving cases with tumors; it is expected that by 2030, these numbers will increase sharply, with 26.4 million new cases and 13.2 million deaths, and 13.2 million deaths with tumors. Survival cases reached 75 million. [0003] As air pollution such as smog, environmental pollution, and food pollution become more and more serious, the spread of cancer in Chin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P35/00
Inventor 徐缓王晓蝉岳洪新栾晓娇苏红吕静
Owner LIAONING NORMAL UNIVERSITY
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