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A kind of anti-acne composition and its application in cosmetics

A composition and anti-acne technology, applied in cosmetics, cosmetic preparations, drug combinations, etc., can solve the problems of vitamin A instability, skin irritation, etc., and achieve the effects of removing pigmentation, dredging pores, and promoting metabolism

Active Publication Date: 2018-10-09
广州市医康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Vitamin A is extremely unstable, easily oxidized and decomposed under light, air, and high temperature, and is irritating to the skin

Method used

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  • A kind of anti-acne composition and its application in cosmetics
  • A kind of anti-acne composition and its application in cosmetics
  • A kind of anti-acne composition and its application in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A preparation process of vitamin A palmitate active substance encapsulated by β-cyclodextrin:

[0038] (1) Dissolving 1kg of β-cyclodextrin in 10kg of water, adding ethanol so that the content of ethanol is 40wt%;

[0039] (2) Add vitamin A palmitate 3kg, stir at 30 DEG C for 24 hours;

[0040] (3) Filter with a 1000-mesh filter cloth, evaporate the filtrate in a water bath at 56°C under reduced pressure to remove ethanol; dry it in an oven at 50°C to obtain the product.

[0041] A preparation process of azelaic acid active substance encapsulated by β-cyclodextrin:

[0042] (1) Dissolving 1kg of β-cyclodextrin in 10kg of water, adding ethanol so that the content of ethanol is 40wt%;

[0043] (2) Add 3 kg of azelaic acid, and stir for 24 hours at a temperature of 30° C.;

[0044] (3) Filter with a 1000-mesh filter cloth, evaporate the filtrate in a water bath at 56°C under reduced pressure to remove ethanol; dry it in an oven at 50°C to obtain the product.

[0045] A...

Embodiment 2

[0050] An acne-removing gel, comprising the following components by mass percentage:

[0051]

[0052] The vitamin A palmitate active substance, azelaic acid active substance and salicylic acid active substance described herein are active substances encapsulated by β-cyclodextrin prepared in Example 1.

[0053] Preparation process: first heat 1,3-propanediol and methyl ester to dissolve, then add water, dipotassium glycyrrhizinate, carbomer, azelaic acid active substance, salicylic acid active substance, heat to 85°C, stir and dissolve evenly; Add triethanolamine, stir evenly; cool down to 45°C, add vitamin A palmitate active substance, centella asiatica extract, β-glucan in sequence, and stir evenly.

Embodiment 3

[0055] An acne-removing gel, comprising the following components by mass percentage:

[0056]

[0057] The vitamin A palmitate active substance, azelaic acid active substance and salicylic acid active substance described herein are active substances encapsulated by β-cyclodextrin prepared in Example 1.

[0058] Preparation process: first heat 1,3-propanediol and methyl ester to dissolve, then add water, dipotassium glycyrrhizinate, carbomer, azelaic acid active substance, salicylic acid active substance, heat to 85°C, stir and dissolve evenly; Add triethanolamine, stir evenly; cool down to 45°C, add vitamin A palmitate active substance, centella asiatica extract, β-glucan in sequence, and stir evenly.

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Abstract

The invention belongs to the field of cosmetics and particularly discloses acne-removing composition and an application thereof to cosmetics. The acne-removing composition is prepared from components in parts by mass as follows: 0.1-0.5 parts of a vitamin A palmitate active matter, 0.1-1 part of an azelaic acid active matter, 0.1-1 part of a salicylic acid active matter and 0.1-1 part of an Asiatic pennywort herb extract, wherein the vitamin A palmitate active matter, the azelaic acid active matter and the salicylic acid active matter adopt active matters prepared by coating vitamin A palmitate, azelaic acid and salicylic acid respectively. The skin care composition can well penetrate skin surface layers to be absorbed and enter deep layers; all the components are matched in a specific proportion, and multiple contained effect ingredients are blended and cooperate with one another, so that the composition can play comprehensive roles in stripping aged cutin, dredging pores, inhibiting bacteria, diminishing inflammations, controlling oil, promoting metabolism, clearing pigmentation caused by acne and has the excellent acne removal and skin care effect.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to an acne-removing composition and its application in cosmetics. Background technique [0002] Acne, also known as acne, is a chronic inflammatory skin disease that occurs in the hair follicles and sebaceous glands of the face, chest, and back. Its typical skin lesions are acne, papules, pus marks, nodules and cysts. The generation of comedo is closely related to major factors such as excessive sebum secretion, pilosebaceous duct blockage, bacterial infection and inflammatory response. Commonly, after entering puberty, the level of androgen in the human body, especially testosterone, increases rapidly, which promotes the development of sebaceous glands and produces a large amount of sebum; at the same time, abnormal keratinization of the pilosebaceous gland ducts causes duct blockage, sebum discharge obstacles, and the formation of keratin plugs; A variety of microorganisms, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/365A61K8/368A61K8/67A61K8/73A61Q17/00A61Q19/00A61P17/10
CPCA61K8/365A61K8/368A61K8/671A61K8/738A61K8/97A61K2800/56A61Q17/005A61Q19/00A61Q19/008
Inventor 刘纲勇
Owner 广州市医康生物科技有限公司
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