Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Gliquidone-containing medicine combination for treating diabetes and preparation method thereof

A technology of gliquidone and composition, which is applied in the field of pharmaceutical composition for treating diabetes and its preparation, can solve problems such as restricting the use of gliquidone, and achieve the effect of improving therapeutic effect, less side effects, and lowering blood sugar

Inactive Publication Date: 2016-07-27
JINAN BANGWEN MEDICAL TECH
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effect of treating obese diabetes is very good, so it is widely used clinically. The common adverse reactions of gliquidone are gastrointestinal reactions, such as nausea, vomiting, diarrhea, abdominal pain, constipation, abdominal distension, indigestion, heartburn, etc. These adverse reactions are as high as 25%, and this adverse reaction limits the use of gliquidone

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Gliquidone-containing medicine combination for treating diabetes and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038]A kind of pharmaceutical composition for treating diabetes, is made up of the crude drug of following proportioning by weight:

[0039] 30g of gliquidone, 6000g of dill seedlings, 6000g of stalks, 6000g of peach gum, 6000g of cold water flowers through stems.

[0040] The preparation method of the pharmaceutical composition for treating diabetes:

[0041] a. Add dill seedlings, reed pedicles, peach gum, and cold water flowers through the stems to decoct twice, add 7 volumes of water for the first time, decoct for 1.5 hours, add water 5 times the volume of the medicine for the second time, and decoct Boil for 1 hour, combine the decoction and set aside;

[0042] b. Concentrate the decoction solution at 60°C and -0.06Mpa to a clear paste with a relative density of 1.08~1.12, add ethanol until the alcohol content is 75%, leave it for 12 hours, filter, and concentrate the filtrate to a relative density of 1.15~1.20 clear ointment, spray-dried to obtain dry powder;

[0043...

Embodiment 2

[0047] A kind of pharmaceutical composition for treating diabetes, is made up of the crude drug of following proportioning by weight:

[0048] 20g of gliquidone, 7000g of dill seedlings, 5000g of stalks, 7000g of peach gum, and 5000g of cold water flowers through stems.

[0049] The preparation method of the pharmaceutical composition for treating diabetes:

[0050] a. Add dill seedlings, reed pedicles, peach gum, and cold water flowers through the stems to decoct twice, add 8 volumes of water for the first time, decoct for 2 hours, add water 6 times the volume of the medicine for the second time, and decoct Cook for 1.5 hours, combine the decoction liquid, and set aside;

[0051] b. Concentrate the decoction solution at 55°C and -0.08Mpa to a clear paste with a relative density of 1.08~1.12, add ethanol until the alcohol content is 75%, leave it for 12 hours, filter, and concentrate the filtrate to a relative density of 1.15~1.20 clear ointment, spray-dried to obtain dry po...

Embodiment 3

[0056] A kind of pharmaceutical composition for treating diabetes, is made up of the crude drug of following proportioning by weight:

[0057] 40g of gliquidone, 5000g of dill seedlings, 7000g of stalks, 5000g of peach gum, and 7000g of cold water flowers through stems.

[0058] The preparation method of the pharmaceutical composition for treating diabetes:

[0059] a. Add dill seedlings, reed pedicles, peach gum, and cold water flowers through the stems to decoct twice, add 6 volumes of water for the first time, decoct for 1 hour, add water 4 times the volume of the medicine for the second time, and decoct Boil for 0.5 hours, combine the decoction and set aside;

[0060] b. Concentrate the decoction liquid at 65°C and -0.04Mpa into a clear paste with a relative density of 1.08~1.12, add ethanol until the alcohol content is 75%, leave it for 12 hours, filter, and concentrate the filtrate to a relative density of 1.15~1.20 clear ointment, spray-dried to obtain dry powder;

...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of medicine and particularly relates to a gliquidone-containing medicine combination for treating diabetes and a preparation method thereof.The gliquidone-containing medicine combination for treating diabetes is prepared from, by weight, 15-45 parts of gliquidone, 4,000-8,000 parts of seedlings of dill, 4,000-8,000 parts of leaf base of chequershaped indocalamus, 4,000-8,000 parts of gum peach and 4,000-8,000 parts of pilea pumila.The traditional Chinese medicine and gliquidone are combined, the common gastrointestinal tract adverse reactions to gliquidone can be avoided, and the treatment effect on diabetes can be improved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition containing gliquidone for treating diabetes and a preparation method thereof. Background technique [0002] Diabetes is the second killer of modern diseases, and its harm to the human body is second only to cancer. In fact, diabetes itself is not terrible, what is terrible is the complications of diabetes, almost all the harm caused by diabetes comes from its complications. Among the diabetic patients in our country, there are as many as 12 million with high blood pressure, 5 million with stroke, 6 million with coronary heart disease, 450,000 with blindness, and 500,000 with uremia. [0003] Diabetes mellitus is a complex disease of multiple etiologies. It is a syndrome of glucose, protein and lipid metabolism disorders caused by the lack of insulin in the body or the increase of hormones that antagonize insulin, or the inability of insu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/10A61K31/64
CPCA61K36/23A61K9/1652A61K31/64A61K36/185A61K36/73A61K36/899A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘芳
Owner JINAN BANGWEN MEDICAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com