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Light-excited acupoint medicine penetration agent for treating diabetic neuropathy and preparation method

A technology for neuropathy and diabetes, applied to nervous system diseases, medical formulas, medical preparations of non-active ingredients, etc., can solve the problems of lack of species, reduce pain, make preparation and use easily, and avoid liver first pass effect of effect

Inactive Publication Date: 2021-03-16
天津医科大学朱宪彝纪念医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the types of external Chinese medicine preparations clinically used to treat this disease are scarce, and most of them are simple smears, and the drugs cannot be fully absorbed through the skin to play a therapeutic role.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1, a light-excited acupoint penetrating agent for treating diabetic neuropathy, comprising the following traditional Chinese medicine components in parts by weight: 6 parts of Radix Astragali, 2 parts of Codonopsis pilosula, 2 parts of Angelica sinensis, 2 parts of Salvia miltiorrhiza, 2 parts of Radix Paeoniae Alba, osmanthus 2 parts of twigs, 2 parts of Caulis Spatholobus, 2 parts of black snake, 2 parts of raw frankincense, 2 parts of licorice.

[0031] The invention also discloses a preparation method of light-excited acupoint penetrating medicine for treating diabetic neuropathy, which includes the following steps:

[0032] Step 1, weighing each component according to the weight ratio of the components of the traditional Chinese medicine;

[0033] Step 2, add 6 times the amount of water to the weighed Chinese medicine components, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct for 1.5 hours, filter; combine the tw...

Embodiment 2

[0046] Example 2, a light-excited acupoint penetrating agent for treating diabetic neuropathy, including the following traditional Chinese medicine components in parts by weight: 8 parts of raw astragalus, 4 parts of codonopsis, 3 parts of angelica, 4 parts of salvia miltiorrhiza, 3 parts of red peony, osmanthus 3 parts of twig, 4 parts of Caulis Spatholobus, 3 parts of black snake, 4 parts of raw frankincense, and 3 parts of licorice.

[0047] The invention also discloses a preparation method of light-excited acupoint penetrating medicine for treating diabetic neuropathy, which includes the following steps:

[0048] Step 1, weighing each component according to the weight ratio of the components of the traditional Chinese medicine;

[0049] Step 2, add 8 times the amount of water to the weighed Chinese medicine components, decoct for 2 hours, filter; add 8 times the amount of water to the filter residue, decoct for 2 hours, filter; combine the two filtrates, and mix the filtra...

Embodiment 3

[0062] Example 3, a light-excited acupoint penetrating agent for treating diabetic neuropathy, including the following traditional Chinese medicine components in parts by weight: 10 parts of raw astragalus, 6 parts of codonopsis, 4 parts of angelica, 6 parts of salvia miltiorrhiza, 4 parts of red peony root, osmanthus 4 parts of twigs, 6 parts of Caulis Spatholobus, 4 parts of black snake, 6 parts of raw frankincense, 4 parts of licorice.

[0063] The invention also discloses a preparation method of light-excited acupoint penetrating medicine for treating diabetic neuropathy, which includes the following steps:

[0064] Step 1, weighing each component according to the weight ratio of the components of the traditional Chinese medicine;

[0065] Step 2, add 10 times the amount of water to the weighed Chinese medicine components, decoct for 3 hours, filter; add 10 times the amount of water to the filter residue, decoct for 3 hours, filter; combine the two filtrates, and mix the f...

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Abstract

The invention discloses a light-excited acupoint medicine penetration agent for treating diabetic neuropathy and a preparation method. The light-excited acupoint medicine penetration agent is preparedfrom the following traditional Chinese medicine components in parts by weight: 6 to 10 parts of raw radix astragali seu hedysari, 2 to 6 parts of radix codonopsis, 2 to 4 parts of Chinese angelica root, 2 to 6 parts of radix et rhizoma salviae miltiorrhizae, 2 to 4 parts of radix paeoniae rubra and radix paeoniae alba, 2 to 4 parts of ramulus cinnamomi, 2 to 6 parts of caulis spatholobi, 2 to 4 parts of zaocys dhumnade, 2 to 6 parts of raw frankincense and 2 to 4 parts of liquorice root. The invention relates to the technical field of treatment of diabetic complications and in particular provides the light-excited acupoint medicine penetration agent for treating the diabetic neuropathy and the preparation method; aiming at etiology and pathogenesis of diabetic peripheral neuropathy, a traditional Chinese medicine formula has the effects of reinforcing Qi and nourishing blood, dispersing blood stasis and dredging arthralgia, and warming and activating channels and collaterals; a modernhigh molecular biomedical technology is combined and hydrogel with good biocompatibility is used for loading traditional Chinese medicine effective components; and targeted treatment of the diabeticperipheral neuropathy is realized through acupoint directional medicine penetration under the excitation of near-infrared light, the curative effect is improved, toxic and side effects of oral medicine treatment are avoided and pains of patients are reduced.

Description

technical field [0001] The invention relates to the technical field of treatment of diabetic complications, in particular to a light-excited acupoint penetrating agent for treating diabetic neuropathy and a preparation method thereof. Background technique [0002] Diabetic peripheral neuropathy is one of the most common complications of diabetes. It is peripheral nerve damage caused by long-term high blood sugar. It mainly manifests as symmetrical pain, numbness, burning heat, coolness, and paresthesia in the distal extremities. Early hypersensitivity, The hypoesthesia in the later stage will even disappear, which is the main cause of diabetic foot ulcer or amputation, seriously affecting the quality of life of patients. [0003] Modern Western medicine does not have a clear specific drug for the treatment of diabetic peripheral neuropathy. It only uses B vitamins and other nutritional nerve drugs on the basis of controlling blood sugar. Those with severe pain and paresthesi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/65A61K9/06A61P3/10A61P25/02A61K35/583
CPCA61K9/0014A61K9/06A61K35/583A61K36/232A61K36/324A61K36/344A61K36/481A61K36/484A61K36/486A61K36/537A61K36/54A61K36/65A61K36/71A61K47/36A61K2236/331A61K2236/39A61K2236/51A61P3/10A61P25/02A61K2300/00
Inventor 毋中明郑银张军
Owner 天津医科大学朱宪彝纪念医院
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