Traditional Chinese medicine for treating acute suppurative otitis media and preparation method thereof

A technology for suppurative otitis media and traditional Chinese medicine, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, antibacterial drugs, etc., can solve problems such as toxic side effects, poor efficacy, easy recurrence, etc., and achieves difficult recurrence and good therapeutic effect. , the effect of no toxic side effects and adverse reactions

Inactive Publication Date: 2016-11-09
王青青
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above method has a good curative effect, the curative effect is still not good, and due to the large amount of antibiotics used, there will be certain toxic and side effects, and it is easy to relapse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0038] Wherein, when the dosage form of described Chinese medicine is syrup, its preparation method comprises the following steps:

[0039] In the first step, the plum root, olive kernel, mango flower, snow notoginseng, juvenile red, vine and chickweed are mixed according to the stated ratio, and the alcohol concentration is 85% to 85% relative to the mass of the obtained mixture. 95% ethanol, heated and refluxed for 2 to 4 hours, then extracted, filtered to obtain the first filtrate; the filter residue was again heated and refluxed with ethanol with an alcohol concentration of 85% to 95% that was 1 to 2 times the mass of the obtained mixture After 1-2 hours, extract and filter to obtain the second filtrate; combine the first filtrate and the second filtrate, recover ethanol under reduced pressure and concentrate until the concentration of the drug solution is 0.7-0.9g crude drug / mL, using a volume of 5L For elution on a macroporous adsorption resin column, first elute with de...

Embodiment 1

[0047] Embodiment 1: syrup

[0048] Take 200g of plum root, 300g of olive kernel, 120g of Miscanthus japonica, 130g of chrysanthemum, 200g of camphor, 200g of three-clawed dragon, 140g of willow, 120g of snow notoginseng, 260g of red onion, 150g of juvenile red, 220g of vine and Chickweed 180g;

[0049] Its preparation method comprises the following steps:

[0050] In the first step, the plum root, olive kernel, mangzhonghua, snow notoginseng, juvenile red, vine and chickweed are mixed according to the stated ratio, and 90% ethanol with an alcohol concentration of 5 times the mass of the obtained mixture is used, Extract after heating and reflux for 4 hours, filter to obtain the first filtrate; use ethanol with an alcohol concentration of 95% which is twice the mass of the obtained mixture again, heat and reflux for 2 hours, extract and filter to obtain the second filtrate Merge the first filtrate and the second filtrate, reclaim the ethanol under reduced pressure and be con...

Embodiment 2

[0053] Embodiment 2: powder injection

[0054] Take 220g of plum root, 260g of olive kernel, 150g of Miscanthus japonica, 80g of chrysanthemum, 180g of camphor, 240g of three-clawed dragon, 100g of willow, 160g of snow notoginseng, 240g of red onion, 180g of juvenile red, 200g of vine and Chickweed 200g;

[0055] Its preparation method comprises the following steps:

[0056] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 5 μm and nano-sized particles with a volume average particle size of less than 0.1 μm , the powder yield of the mixed powder is at least 95%;

[0057] The second step is to add ethanol with an alcohol concentration of 85% relative to the quality of the mixed powder which is 3 times the mass of the mixed powder obtained in the first step, stir and dissolve to obtain an ethanol solution, and put ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating acute suppurative otitis media and a preparation method thereof. The traditional Chinese medicine is prepared from Japanese plum roots, olive kernels, hypericum patulum, scabrous mosla herb, litsea rotundifolia, cayratia trifolia, salix hypoleuca, rheum lidjiangense, eleutherine americana, ardisia alyxiaefolia, gongronema nepalense and stellaria media. The traditional Chinese medicine has the advantages that based on the theory of traditional Chinese medicine, the treatment effect on acute suppurative otitis media is good, no toxic or side effect or adverse reaction exists, and relapse is not likely to occur after curing.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating acute suppurative otitis media and a preparation method thereof. Background technique [0002] Suppurative otitis media is a suppurative inflammation of the middle ear mucosa, which occurs frequently in children and is also a common cause of hearing loss in children. Acute suppurative otitis media is a common infectious disease in childhood, with a high incidence rate, easy recurrence, and many complications and sequelae. Auxiliary examinations such as otoscopy and ear palpation are helpful for the diagnosis of suppurative otitis media. Infection control, unobstructed drainage, and removal of the cause are the principles of treatment. [0003] Bacteria enter the tympanum and cause suppurative infection, which is called acute suppurative otitis media. It is mostly secondary to upper...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P31/04A61P27/16
CPCA61K36/736A61K36/185A61K36/27A61K36/32A61K36/36A61K36/53A61K36/54A61K36/708A61K36/76A61K36/87A61K36/88A61K2236/15A61K2236/331A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 王青青武静宋相孔
Owner 王青青
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