Pharmaceutical composition for treating acute and chronic viral hepatitis as well as preparation method and application thereof

A composition and drug technology, applied in the directions of drug combination, pharmaceutical formula, antiviral agent, etc., can solve the problems of complex composition and high cost, and achieve the effect of simple composition and low cost

Inactive Publication Date: 2016-11-16
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned composition has disadvantages such as complex composition and high cost, which limit its application.

Method used

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  • Pharmaceutical composition for treating acute and chronic viral hepatitis as well as preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0046]250g capillary, 200g gentian, 100g gardenia, 25g skullcap, 50g licorice, 45g rhubarb, 45g fried white peony, 4g Pien Tze Huang;

[0047] The preparation method of this pharmaceutical composition comprises the following steps:

[0048] Take capillary, gentian, gardenia, scutellaria baicalensis and licorice of selected weight respectively, add water and heat and reflux to extract twice, based on the total weight of capillary chen, gentian, gardenia, scutellaria baicalensis and licorice, add 2 weight Double the amount of water to extract for 2 hours, combine the extracts, and filter to obtain filtrate A;

[0049] Concentrate the filtrate A to a concentrated solution A with a relative density of 1.15 to 1.23 at 70-80° C., then add ethanol until the alcohol content is 70%, let it stand for 12 hours, and filter to obtain a filtrate B....

Embodiment 2

[0053] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0054] 200g capillary, 240g gentian, 75g gardenia, 30g baicalin, 40g licorice, 54g rhubarb, 36g fried white peony, 7g Pien Tze Huang;

[0055] The preparation method of this pharmaceutical composition comprises the following steps:

[0056] Take capillary, gentian, gardenia, scutellaria baicalensis and licorice with selected weights respectively, add water and heat and reflux to extract once, based on the total weight of capillary chen, gentian, gardenia, scutellaria baicalensis and licorice, add 5 weight Double the amount of water to extract for 1 hour, combine the extracts, and filter to obtain filtrate A;

[0057] Concentrate the filtrate A to a concentrated solution A with a relative density of 1.15 to 1.23 at 70-80° C., then add ethanol until the alcohol content is 80%, let it stand for 12 hours, and filter to obtain a filtrate B...

Embodiment 3

[0061] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0062] Capillary 300g, gentian 160g, gardenia 125g, scutellaria baicalensis 20g, licorice 60g, rhubarb 36g, fried white peony root 54g, Pien Tze Huang 1g;

[0063] The preparation method of this pharmaceutical composition comprises the following steps:

[0064] Take capillary, gentian, gardenia, scutellaria baicalensis and licorice with selected weights respectively, add water and heat and reflux to extract 5 times, based on the total weight of capillary chen, gentian, gardenia, scutellaria baicalensis and licorice, add 1 weight each time Double the amount of water to extract for 5 hours, combine the extracts, and filter to obtain filtrate A;

[0065] Concentrate the filtrate A to a concentrated solution A with a relative density of 1.15 to 1.23 at 70-80° C., then add ethanol until the alcohol content is 60 to 80%, let stand for 12 ho...

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Abstract

The invention relates to a pharmaceutical composition for treating acute and chronic viral hepatitis as well as a preparation method and application thereof. The pharmaceutical composition comprises the following raw medicines in parts by weight: 150-350 parts of oriental wormwood, 120-280 parts of gentiana scabra bunge, 50-150 parts of gardenia jasminoides ellis, 15-35 parts of baikal skullcap roots, 30-70 parts of licorice roots, 27-63 parts of rhubarb, 27-63 parts of fried white peony roots and 0.1-10 parts of anti-inflammatory and analgesic bolus. According to the pharmaceutical composition, the channel tropism as well as nature and flavor of each traditional Chinese medicine are fully considered, and all traditional Chinese medicines are mutually proportioned and matched according to the assistant and guide matching relation so as to be synergistic, thereby playing a role in treating acute and chronic viral hepatitis; and the pharmaceutical composition only comprises eight raw medicines, so that the composition is simple and the cost is relatively low.

Description

technical field [0001] The invention belongs to the field of medicaments, and in particular relates to a pharmaceutical composition for treating acute and chronic viral hepatitis, a preparation method and application thereof. Background technique [0002] Viral hepatitis is an inflammatory disease of the liver caused by hepatitis A, B, C, D, and E viruses. Clinically, it mainly manifests as fatigue, loss of appetite, nausea, vomiting, hepatomegaly, and liver function damage. Some patients may have jaundice It has the characteristics of strong infectivity, complex transmission routes, wide epidemic range, and high incidence rate. Taking China as an example, about 500,000 to 600,000 new viral hepatitis patients are added each year. All hepatitis viruses can cause acute hepatitis. In addition, hepatitis B, C, and D viruses can also cause chronic hepatitis, which can lead to cirrhosis, liver failure, and liver cancer. [0003] Chinese patent document CN104524054A discloses: a ...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61K9/48A61K9/20A61K9/00A61K9/14A61P1/16A61P31/14A61P31/20A61K35/413A61K35/55A61K35/583
CPCA61K36/28A61K9/0095A61K9/143A61K9/204A61K9/4841A61K35/413A61K35/55A61K35/583A61K36/258A61K36/484A61K36/515A61K36/539A61K36/65A61K36/708A61K36/71A61K36/744A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 洪绯于娟袁慧君张栋梁
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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