Nasal spray product for treating or preventing cold and application thereof

A technology for preventing colds and nasal cavity. It is used in medical preparations with non-active ingredients, aerosol delivery, and respiratory diseases. It can solve problems such as human injury and organ injury, and achieve non-irritating, cold prevention, and non-infectious diseases. Sensitivity effect

Inactive Publication Date: 2017-02-01
JIANG SU PHARMAMAXCORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment of colds by drugs usually has certain harm to the human body, for examp

Method used

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  • Nasal spray product for treating or preventing cold and application thereof
  • Nasal spray product for treating or preventing cold and application thereof
  • Nasal spray product for treating or preventing cold and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0036] Example 1

[0037] In the present embodiment, the proportioning ratio of the composition of the present invention is shown in the following table 1:

[0038] Table 1

[0039]

[0040] Preparation Process:

[0041] ① Dissolve polyvinylpyrrolidone-vinyl acetate copolymer in 30g of hot purified water to fully disperse, and then add 20g of purified water to fully swell;

[0042] ② Dissolve glycerin, peppermint oil, Tween 80, zinc edetate, sodium chloride, succinic acid and disodium succinate in 30 g of purified water;

[0043] ③ Mix step ① and step ② evenly, and add purified water until the total weight of the solution is 100g;

[0044] ④ Then put the solution into a spray bottle.

[0045] After testing, the pH value of the prepared composition was 3.6.

Example Embodiment

[0046] Example 2

[0047] In the present embodiment, the proportioning ratio of the composition of the present invention is shown in the following table 2:

[0048] Table 2

[0049] Element specific name weight gel matrix Hypromellose 0.1g Osmotic pressure regulator glucose 2g moisturizer Pyrrolidone carboxylic acid 1g Surfactant Tween 80 0.5g Auxiliary Ingredients - Flavorings aspartame 0.4g Auxiliary Ingredients - Flavorings Acesulfame 0.4g pH buffer Citric acid 0.03g pH buffer Sodium citrate 0.01g Auxiliary Ingredient - Cooling Agent ws-23 0.02g Auxiliary Ingredients - Cell Nutrients Sodium pyruvate 1g solvent purified water Add water to a total weight of 100g

[0050] Preparation Process:

[0051] ①Add the gel matrix to 30g of hot purified water to fully disperse, and then add 20g of purified water to fully swell;

[0052] ②Add other materials to 30g of purified wat...

Example Embodiment

[0056] Example 3

[0057] In the present embodiment, the proportioning ratio of the composition of the present invention is shown in the following table 3:

[0058] table 3

[0059]

[0060] The preparation process is the same as in Example 2.

[0061] After testing, the pH value of the prepared composition was 3.0.

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PUM

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Abstract

The invention provides a nasal spray product for treating or preventing cold, which includes a composition for treating or preventing cold and a nasal spray container for accommodating the composition. Spray angle, which is formed through the container, of the composition is less than 30 degrees. The composition includes a gel substrate and a pH buffer agent. The pH of the composition is higher than 2.5 and lower than 4.0. The invention also provides an application of the composition in preparation of a medicine for treating or preventing cold, wherein the composition can prevent cold and alleviate early-stage symptoms of the cold through physical effects.

Description

technical field [0001] The invention relates to a nasal cavity spray product, which comprises a composition for treating or preventing colds and a nasal cavity spray container for containing the composition. The composition of the invention does not contain any active pharmaceutical ingredients, and prevents and relieves cold symptoms through physical action. The invention also relates to the use of said composition. Background technique [0002] A cold is a common respiratory disease caused by a cold virus. It begins when the virus contacts the mucous membrane of the nose or throat. The body’s immune system releases a large number of white blood cells to fight inflammation. The main symptoms are sneezing, runny nose, nasal congestion, sore throat, cough, headache, chills and myalgia. Colds are highly contagious and mainly spread viruses through air droplets. [0003] Medications for colds include antivirals, such as oxaletamivir, acyclovir, and amantadine; drugs for feve...

Claims

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Application Information

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IPC IPC(8): A61K9/12A61K47/32A61K47/38A61K47/36A61K47/12A61P31/16A61P11/00
CPCA61K9/0043A61K9/12A61K47/12A61K47/32A61K47/36A61K47/38
Inventor 蒋志君汪磊李连利陆小娟秦飞
Owner JIANG SU PHARMAMAXCORP
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