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Saponin-containing compound antiviral oral liquid and preparation method thereof

An antiviral oral liquid and saponin technology, applied in the field of medicine, can solve problems such as toxic and side effects, achieve low toxicity, improve main symptoms, and have good curative effects

Inactive Publication Date: 2017-05-10
张可池
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many antiviral drugs clinically, and all of them have a certain effect, but they have great toxic and side effects at the same time.

Method used

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  • Saponin-containing compound antiviral oral liquid and preparation method thereof
  • Saponin-containing compound antiviral oral liquid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Weigh 10 parts of sapindus saponins, 6 parts of alfalfa saponins, 6 parts of astragalosides, 10 parts of tribulus terrestris saponins, 3 parts of tea saponins, 4 parts of bitter melon saponins, 6 parts of Panax notoginseng saponins, and 3 parts of ginseng stem and leaf saponins , 4 parts of gypenoside, 6 parts of soybean saponin, 6 parts of codonopsis saponin, 3 parts of total saponin of Achyranthes bidentata, 6 parts of saikosaponin A, 1 part of total saponin of Patrinia and 1 part of mogroside, add water and correct the taste After being mixed evenly, the saponin compound antiviral oral liquid is prepared by sterilizing and filling; wherein the total saponin content is 1 mg / mL.

Embodiment 2

[0014] Weigh 13 parts of sapindus saponins, 9 parts of alfalfa saponins, 9 parts of astragalosides, 15 parts of tribulus terrestris saponins, 5 parts of tea saponins, 6 parts of bitter melon saponins, 9 parts of Panax notoginseng saponins, and 5 parts of ginseng stem and leaf saponins , 6 parts of gypenoside, 9 parts of soybean saponin, 9 parts of codonopsis saponin, 5 parts of total saponin of Achyranthes bidentata, 9 parts of saikosaponin A, 2 parts of total saponin of Patrinia and 2 parts of mogroside, add water and correct the taste After being mixed evenly, the saponin compound antiviral oral liquid is prepared by sterilizing and filling; wherein the total saponin content is 1 mg / mL.

Embodiment 3

[0016] Weigh 11 parts of Sapindus saponins, 8 parts of alfalfa saponins, 7 parts of astragalosides, 12 parts of Tribulus terrestris saponins, 4 parts of tea saponins, 5 parts of bitter melon saponins, 8 parts of Panax notoginseng saponins, and 4 parts of ginseng stem and leaf saponins , 5 parts of gypenoside, 8 parts of soybean saponin, 7 parts of codonopsis saponin, 4 parts of total saponin of Achyranthes bidentata, 8 parts of saikosaponin A, 1.5 parts of total saponin of Patrinia and 1.5 parts of mogroside, add water and correct the taste After being mixed evenly, the saponin compound antiviral oral liquid is prepared by sterilizing and filling; wherein the total saponin content is 1 mg / mL.

[0017] One, the toxicology research of saponin compound antiviral oral liquid of the present invention

[0018] Acute toxicity study: The saponin compound antiviral oral liquid prepared in Examples 1, 2, and 3 was used in the experiment, and the maximum dose of 0.3ml / 10g body weight of ...

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Abstract

The invention discloses saponin-containing compound antiviral oral liquid. The saponin-containing compound antiviral oral liquid comprises 10-13 parts of soapnut saponin, 6-9 parts of alfalfa saponin, 6-9 parts of astragalus saponin, 10-15 parts of tribulus terrestris saponin, 3-5 parts of tea saponin, 4-6 parts of momordicosides, 6-9 parts of total saponins of panax notoginseng, 3-5 parts of ginseng stem-leaf saponin, 4-6 parts of gypenoside, 6-9 parts of soybean saponin, 6-9 parts of Radix Codonopsis saponin, 3-5 parts of total saponins of achyranthes, 6-9 parts of saikosaponin, 1-2 parts of total patrinia saponin and 1-2 parts of triterpene glucoside. The saponin-containing compound antiviral oral liquid, selecting 15 kinds of saponins for compatibility carefully, can improve main symptoms of viral infection remarkably, and is capable of reducing fever quickly, excellent in antiviral effect, remarkably effective in treatment of various viral infections and free of damage to the liver and the kidney, drug eruption and other toxic and side effects, and the total effective rate is 96.3%.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a saponin compound antiviral oral liquid and a preparation method thereof. Background technique [0002] Viruses are a type of non-cellular microorganisms with small particles, measured in nanometers, simple structure, strict parasitic nature, and reproduction by replication. Viruses are microorganisms that are smaller than bacteria, have no cell structure, and can only multiply in cells. They are composed of proteins and nucleic acids. When the virus contacts the host cell, it takes off the protein coat, and its nucleic acid (gene) invades the host cell, and with the help of the latter's replication system, it replicates new viruses according to the instructions of the viral gene. [0003] In recent years, the incidence of viral diseases has become higher and higher, and spread rapidly, such as influenza, mumps, measles, polio and infectious hepatitis caused by viruses, whic...

Claims

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Application Information

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IPC IPC(8): A61K36/84A61K9/08A61P31/12A61P31/16A61P31/14A61P31/20A61K31/7048
CPCA61K36/77A61K9/0053A61K9/08A61K31/7048A61K36/185A61K36/21A61K36/258A61K36/344A61K36/42A61K36/424A61K36/48A61K36/481A61K36/82A61K36/84A61K2300/00
Inventor 张培红张可池
Owner 张可池
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