Hangover alleviating traditional Chinese medicine composition and application

A composition and technology of traditional Chinese medicine, applied in the field of anti-alcoholic traditional Chinese medicine composition and application, to achieve the effect of stabilizing the effect of applied technology

Inactive Publication Date: 2017-05-24
CHINA TOBACCO GUANGDONG IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are no research reports on the anti-alcoholic application of Hovenia dul...

Method used

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  • Hangover alleviating traditional Chinese medicine composition and application
  • Hangover alleviating traditional Chinese medicine composition and application
  • Hangover alleviating traditional Chinese medicine composition and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Example 1 Animal Drunkenness Experimental Model Establishment

[0054] In order to make the results of animal intoxication and hangover experiments scientific and repeatable, this paper establishes an animal intoxication experimental model of the relationship between the dose of alcohol used in the experiment and the phenomenon of animal intoxication, which is used for the research and evaluation of anti-alcohol substances. The specific content of the established model is mainly to determine the appropriate intragastric dose for drunken mice and determine the lethal intragastric dose for mice.

[0055] 1 Experimental materials

[0056] SPF-grade Kunming mice, weighing 20-25 g, male, were purchased from Shanghai Slack Experimental Animal Co., Ltd. (purchased from the Experimental Animal Center of Second Military Medical University).

[0057] 2 Main reagents and instruments

[0058] 56 ° Red Star Erguotou (Beijing Red Star Co., Ltd.), mouse gavage device, 1 ml syringe, ...

Embodiment 2

[0077] The preparation of embodiment 2 hovenia dulcis, kudzu flower, kudzu root extract

[0078] 2.1 Raw materials of Chinese herbal medicine

[0079] Pueraria lobata, Pueraria lobata, and Hovenia dulcis were purchased from Zhongda Pharmacy of Shanghai Leiyun Shangbei District Pharmaceutical Co., Ltd., respectively.

[0080] 2.2 Main reagents and instruments

[0081] Absolute ethanol (Sinopharm Chemical Reagent Co., Ltd.), 75% ethanol, deionized water (MiliQ pure water), acetonitrile, methanol, 0.1% phosphoric acid, pulverizer, 50-mesh sieve, rotary evaporator, Soxhlet extractor, 65 ℃ oven.

[0082] Preparation of puerarin standard product: Accurately weigh 1.97 mg of puerarin standard product (purchased from Shanghai Yuanye Biotechnology Co., Ltd.), dry at 60°C for 8 hours, dilute to 2 mL with 30% ethanol, take 1 mL to a 10 mL volumetric flask, That is, a 0.0985mg / mL puerarin reference solution was obtained.

[0083] Preparation of irisin standard substance: Accurately we...

Embodiment 3

[0115] Embodiment 3 optimal proportioning experiment

[0116] 1 test material

[0117] Kunming mice (KM mice), weighing 20-25 g, male, were purchased from Shanghai Slack Experimental Animal Co., Ltd. (purchased from the Experimental Animal Center of Second Military Medical University).

[0118] 56 degrees Red Star Erguotou (Beijing Red Star Co., Ltd.), deionized water, mouse gavage device, 1 ml syringe, EP tube, pipette gun, pipette tip.

[0119] Preparation of positive control substance corn peptide solution: take 0.9g corn peptide and dissolve in 3mL deionized water to obtain 0.3g / mL corn peptide solution;

[0120] Preparation of Positive Control Substance Neptune Golden Bottle Solution: Take 3 pieces of Neptune Golden Bottle (Shanghai Dekang Medicine Store), crush them, dissolve in 4mL deionized water, and obtain 0.75g / mL Neptune Golden Bottle solution.

[0121] 2 Animals and their management

[0122] After the mice were purchased, they were acclimatized in the animal ro...

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Abstract

The invention discloses a hangover alleviating traditional Chinese medicine composition and an application. The hangover alleviating traditional Chinese medicine composition consists of an ethanol extract of semen hoveniae, an ethanol extract of flos puerariae and an ethanol extract of radix puerariae. In the invention, the flos puerariae and semen hoveniae serve as monarch drugs while radix puerariae as a minister drug; on the basis, the three are extracted according to a scientific proportion and then accurately combined to realize a remarkable synergistic effect; and a hangover alleviating traditional Chinese medicine composition with simple and clear composition and good technical effect is successfully obtained.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, and more specifically, relates to a Chinese medicine composition for hangover and its application. Background technique [0002] Wine is highly valued in traditional Chinese medicine. Traditional Chinese medicine has long discovered that wine can unblock blood vessels and act as medicine. It is not only used to concoct medicine, but also used as a common product in prescriptions. In the medical literature of the motherland, there are many records about wine, and many herbal books have elaborated on wine from both advantages and disadvantages. The ancients said that "wine is made of water and rice, and it should be harmless. However, it must be brewed with rice cakes, or steamed with water and fire, and the humidity will be dry, so the heat is poisonous." In fact, after fermentation, the grains and fruits used to make wine will be transformed into ethanol, methanol, alcohol o...

Claims

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Application Information

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IPC IPC(8): A61K36/72A61P39/02
CPCA61K36/72A61K36/488A61K2236/333A61K2236/51A61K2300/00
Inventor 黄菲陶红周瑢潘晓薇陆一鸣曾静伍锦鸣
Owner CHINA TOBACCO GUANGDONG IND
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