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Application of berberine in preparation of medicine for treating acute soft tissue damage

A soft tissue injury and berberine technology, applied in the field of natural medicine, can solve the problems of no berberine preparations on the market, and no published patent documents for berberine acute soft tissue injury, etc., to achieve a stable blood drug concentration curve and reduce inflammation exudation Liquid, the effect of relieving pain symptoms

Inactive Publication Date: 2017-05-31
FOSHAN HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no literature reporting that berberine can be used to treat acute soft tissue injury. After searching, there is no patent document that discloses berberine for the treatment of acute soft tissue injury, and there is no preparation that uses berberine as a drug for treating acute soft tissue injury.

Method used

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  • Application of berberine in preparation of medicine for treating acute soft tissue damage
  • Application of berberine in preparation of medicine for treating acute soft tissue damage
  • Application of berberine in preparation of medicine for treating acute soft tissue damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The preparation of embodiment 1-lotion

[0016] Prescription: berberine hydrochloride (active ingredient) 10kg, ethylparaben (preservative) 1kg, sodium benzoate (preservative) 2kg, appropriate amount of distilled water (solvent).

[0017] Preparation method: Dissolve the active ingredient and other auxiliary materials in distilled water, set the volume to 1000L, subpackage, and sterilize to obtain the product.

[0018] How to use: Dip gauze or cotton swab into the liquid medicine, wash or wet compress the affected area, twice a day.

Embodiment 2

[0019] The preparation of embodiment 2-lotion

[0020] Prescription: berberine hydrochloride (active ingredient) 11kg, ethylparaben (preservative) 1kg, sodium benzoate (preservative) 2kg, appropriate amount of distilled water (solvent).

[0021] Preparation method: Dissolve the active ingredient and other auxiliary materials in distilled water, set the volume to 1000L, subpackage, and sterilize to obtain the product.

[0022] How to use: Dip gauze or cotton swab into the liquid medicine, wash or wet compress the affected area, twice a day.

Embodiment 3

[0023] The preparation of embodiment 3-lotion

[0024] Prescription: berberine hydrochloride (active ingredient) 13kg, ethylparaben (preservative) 1kg, sodium benzoate (preservative) 2kg, appropriate amount of distilled water (solvent).

[0025] Preparation method: Dissolve the active ingredient and other auxiliary materials in distilled water, set the volume to 1000L, subpackage, and sterilize to obtain the product.

[0026] How to use: Dip gauze or cotton swab into the liquid medicine, wash or wet compress the affected area, twice a day.

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PUM

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Abstract

The invention relates to a medicine of isoquinoline alkaloid, and particularly relates to an application of berberine in preparation of a medicine for treating acute soft tissue damage. The medicine is prepared from the berberine and pharmaceutically acceptable auxiliary materials, wherein the content of the berberine in percentage by weight is 1-99.5%. The dosage form of the medicine is an external preparation of a lotion, a spray, an ointment, gel and the like. The medicine is specific in function, free of toxic or side effect and promising in market prospect, and the disease prevention and treatment range of the berberine is expanded.

Description

technical field [0001] The invention relates to the technical field of natural medicines, in particular to the application of berberine in the preparation of medicines for treating acute soft tissue injuries. Background technique [0002] Berberine, also known as berberine, is an important alkaloid, which can be extracted from traditional Chinese medicines with a long history of application in my country (such as Coptis chinensis, Cortex Phellodendron, Sangezhen, etc.). It is widely distributed in the plant kingdom, and this product is found in about 4 families and 10 genera. The clinical application is mainly the hydrochloride and sulfate of this product. my country's current mass production of synthetic methods. Berberine is a broad-spectrum antibacterial agent, and has the effect of strengthening leukocyte phagocytosis of Staphylococcus aureus, can resist pathogenic microorganisms, and has inhibitory effects on various bacteria such as Shigella, Mycobacterium tuberculos...

Claims

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Application Information

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IPC IPC(8): A61K31/4375A61P29/00A61P19/04
CPCA61K31/4375
Inventor 刘效仿余俊文李子鸿李怀国刘东文郑芳昊刘礼初李雪蔡立雄
Owner FOSHAN HOSPITAL OF TCM