Preparation method and application of easy-to-suture array microtubular nerve regeneration stent

Abstract

The invention discloses a preparation method and application of an easy-to-suture array microtubular nerve regeneration stent. The preparation method comprises the following steps: preparation of an array microtubular inner core, preparation of an electrostatic spinning easy-to-suture nerve stent skin structure, and preparation of the easy-to-suture array microtubular nerve regeneration stent. A regeneration method comprises the following steps that an array microtubular nerve stent physically guides nerve regeneration by use of longitudinally and parallelly arranged array mocrotubular structures; and the easy-to-suture nerve stent skin structure wraps the array microtubular nerve stent to achieve nerve stuffing and is used for suturing of nerve stumps and a bridging stent. Through changes of matching between an array microtubular inner core die and an electrostatic spinning receiving steel bar, the easy-to-suture array microtubular nerve regeneration stent with the length of 10-100 mm and the internal diameter of 1-8 mm can be prepared, and spaces reserved at two ends of the easy-to-suture nerve stent skin structure are 1-5 mm, and stuffing suture of the nerve stumps is facilitated.

Description

technical field [0001] The invention belongs to the field of medical technology, and in particular relates to a preparation method and application of an easy-to-suture array microtube nerve repair support. Background technique [0002] Peripheral nerve injury is one of the most serious traumas clinically. The number of peripheral nerve cases caused by various reasons in our country is huge every year. According to statistics, there are about 2 million cases of peripheral nerve injury in my country every year due to severe trauma, congenital deformity and tumor resection; according to the estimate of Integra Life Science, the global market for nerve repair is about 4 billion US dollars. With the development of modern industry, transportation and construction, the incidence of peripheral nerve injury is increasing year by year, which brings a heavy burden to individuals, families and society. Although peripheral nerves can spontaneously regenerate after injury and re-establi...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide an easy-to-suture array microtube nerve repair scaffold preparation method and its application, aiming at solving the problem of lack of internal three-dimensional structure of the current commercial nerve guide and the array microtube nerve scaffold is not conducive to nerve suturing, and the operation time is long. Suture strength is not enough, it is difficult to apply in clinical practice

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