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Nanocomposite material and preparing method and application thereof

A nano-composite material and carbon nano-material technology, applied in the field of nano-composite materials and their preparation, can solve problems such as poor lipase immobilization ability, and achieve the effects of good sensitivity and simple preparation process

Active Publication Date: 2017-08-11
SOUTHWEST UNIVERSITY
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Problems solved by technology

[0004] The purpose of the present invention is to solve the complicated process of making triglyceride sensor materials and the poor immobilization ability of materials to lipase, and considering the practical significance of sensor industrialization, to develop a new type of triglyceride sensor with strong adsorption capacity for lipase Sexual nanocomposites, and applications

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  • Nanocomposite material and preparing method and application thereof
  • Nanocomposite material and preparing method and application thereof

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Embodiment Construction

[0034] In order to make the purpose, technical solutions and advantages of the present invention clearer, the following technical solutions in the present invention are clearly and completely described. Obviously, the described embodiments are some embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0035] In this example, a nano-gold / polydopamine / graphene (AuNPs / PDA / RGO) nanocomposite material was synthesized, which can immobilize lipase well to directly detect triglycerides. In addition, the sensor prepared by this project The use of screen-printed electrodes makes it have a good industrial application prospect. In the embodiment of the present invention, graphene oxide is used as a carrier, and a polydopamine film is synthesized on its surface by a chemic...

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Abstract

The invention provides a nanocomposite material and a preparing method and application thereof. The method comprises the following steps of 1, preparing a multi-layer pore structure carbon nanomaterial modified by polydopamine; 2, distributing nano-metal particles on the modified material obtained in the step 1. According to the nanocomposite material and the preparing method and application thereof, the synthetized nanocomposite material can well fix lipase, thus triglyceride is directly detected, and in addition, according to a sensor prepared through the nanocomposite material, a screen-printed electrode is adopted, so that the nanocomposite material has a good industrialized application prospect. The nanocomposite material can well combine lipase, and the screen-printed electrode of which a work electrode is modified with the nanocomposite material shows good sensitivity, selectivity and capacity of resisting disturbance on the detection of triglyceride. Besides, the preparing process of the nanocomposite material is simple, and the screen-printed electrode has the advantages of being flexible, convenient to carry and the like; because of the disadvantages, a triglyceride sensing chip has a wide industrialized application prospect.

Description

technical field [0001] The invention relates to the field of material technology, in particular to a nanocomposite material and its preparation method and application. Background technique [0002] Triacylglyceride (TG) is the most abundant lipid in the human body. Most tissues can use triglyceride decomposition products to supply energy. At the same time, tissues such as liver and fat can also synthesize triglyceride. In adipose tissue storage. The level of triglycerides can be divided into four grades: normal level <1.69mM / L; critical high level is 1.69-2.25mM / L; high level is 2.26-5.63mM / L; extremely high level is ≥5.64mM / L. Patients with borderline high and high levels of triglycerides are often accompanied by lipid disorders that increase the risk of coronary heart disease, such as familial complex hyperlipidemia and diabetic lipid disorders. Patients with triglyceride levels higher than 11.3mM / L have a significantly increased risk of acute pancreatitis. In middle...

Claims

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Application Information

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IPC IPC(8): G01N27/327G01N27/48B82Y30/00B82Y40/00
CPCB82Y30/00B82Y40/00G01N27/3278G01N27/48
Inventor 李长明史转转
Owner SOUTHWEST UNIVERSITY
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