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Hydroxytyrosol-containing blood fat-reducing composition and application thereof

A technology of hydroxytyrosol and composition, which is applied in the field of hydroxytyrosol composition, can solve the problems of low purity, low content of hydroxytyrosol, and high cost for consumers to take, so as to prevent and treat hyperlipidemia and protect the cardiovascular and cerebrovascular systems , the effect of reasonable compatibility

Inactive Publication Date: 2017-09-15
SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] After a large amount of market research, the inventor found that there are many varieties of health care products of hydroxytyrosol and its precursor oleuropein on the market, but most of them use hydroxytyrosol extracts with lower purity as raw materials
For example, the hydroxytyrosol freeze-dried powder widely sold in the market, in which the total content of hydroxytyrosol is 2.5% to 20%, and other ingredients are oleuropein and various alkaloids, and their existence affects the color and taste of the product , making it difficult to monitor the quality of the product; in addition, the content of hydroxytyrosol is low, and to achieve a better health care effect, a large amount of low-concentration products of hydroxytyrosol must be taken, and the cost of taking it for consumers is high.

Method used

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  • Hydroxytyrosol-containing blood fat-reducing composition and application thereof
  • Hydroxytyrosol-containing blood fat-reducing composition and application thereof
  • Hydroxytyrosol-containing blood fat-reducing composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take 3g of hyaluronic acid, 40g of arginine, and 5g of citrulline, mix them with a pulverizer, pass through a 60-mesh sieve, and dissolve 1g of hydroxytyrosol in 80% ethanol as a wetting agent to prepare a soft material, granulate, and dry (50° C.), pass through a 30-mesh sieve and granulate to obtain a blood lipid-lowering composition containing hydroxytyrosol.

Embodiment 2

[0030] Take 5g of hyaluronic acid, 50g of arginine, and 10g of citrulline, mix them with a pulverizer and pass through a 60-mesh sieve, take 2g of hydroxytyrosol and dissolve them in 80% ethanol as a wetting agent to prepare a soft material, granulate, and dry (50° C.), pass through a 30-mesh sieve and granulate to obtain a blood lipid-lowering composition containing hydroxytyrosol.

Embodiment 3

[0032] Take 13g of hyaluronic acid, 80g of arginine, and 20g of citrulline, mix them with a pulverizer and pass through a 60-mesh sieve, take 3g of hydroxytyrosol and dissolve them in 80% ethanol as a wetting agent to prepare a soft material, granulate, and dry (50° C.) for 30 minutes, pass through a 30-mesh sieve and granulate to obtain a blood lipid-lowering composition containing hydroxytyrosol.

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PUM

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Abstract

The invention discloses a hydroxytyrosol-containing blood fat-reducing composition which is characterized by being prepared from hydroxytyrosol, hyaluronic acid, arginine and citrulline according to a certain ratio. The composition can increase the content of high-density lipoprotein cholesterol in blood and reduce the content of low-density lipoprotein cholesterol. The invention further provides application of the hydroxytyrosol composition in preparation of a medicine and a health product which have blood fat reducing and oxidization resisting functions, and application of the hydroxytyrosol composition in preparation of a medicine and a health product which can assist in preventing and treating cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention belongs to the technical field of health care products, and specifically relates to the preparation of a hydroxytyrosol composition and its application by using hydroxytyrosol as a functional factor in combination with hyaluronic acid, arginine and citrulline. Background technique [0002] Cardiovascular and cerebrovascular diseases are common diseases among middle-aged and elderly people, and 15 million people die of cardiovascular and cerebrovascular diseases in the world every year. The pathogenic mechanism of cardiovascular and cerebrovascular diseases is mainly that the oil and cholesterol in the blood deposit on the blood vessel wall, causing the diameter of the blood vessel to become smaller and blocking the passage of blood, and then coronary heart disease and other cardiovascular and cerebrovascular diseases occur. High-density lipoprotein cholesterol (HDL-C) is the "scavenger" in the blood vessels, which can transport the choles...

Claims

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Application Information

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IPC IPC(8): A61K31/728A61K31/198A61K31/05A61P9/00A61P9/10A61P3/06A61P39/06A23L33/175A23L33/125A23L33/105
CPCA23L29/30A23L33/105A23L33/125A23L33/175A23V2002/00A61K31/05A61K31/198A61K31/728A61K2300/00A23V2200/326A23V2200/3262A23V2200/30A23V2250/2132A23V2250/0606A23V2250/0614A23V2250/51
Inventor 郭新艳孟祥璟边玲王丽丽刘少英张祥奎吴季栩朱希强凌沛学
Owner SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES
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