Intrusive medical catheter with markers and manufacturing method of intrusive medical catheter
A medical catheter, interventional technology, applied in the direction of catheter, coating, etc., can solve the problems of difficult identification, surface convex and concave ink falling off, etc., and achieve the effect of fine production, bright color and firm adhesion
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[0042] The preparation method of the marked interventional medical catheter provided by the present invention comprises the following steps:
[0043] (1) Freshly prepare the marking layer material: uniformly disperse the photosensitizer and the contrast agent in the biocompatible polymer material substrate of the marking layer to obtain the freshly prepared marking layer material;
[0044] Preferably, the photosensitizer is uniformly dispersed in the biocompatible polymer material substrate of the marking layer, specifically:
[0045] (1-1) Add the base material, and the pre-broken and wet photosensitizer according to the formula to the high-speed mixer, so as to evenly adhere to the polymer base material;
[0046] (1-2) Stir and cool the substrate and photosensitizer mixture obtained in step (1-1) until the mutual adhesion between the particles of the mixture is released.
[0047] Said uniformly dispersing the contrast agent in the marking layer biocompatible polymer materia...
Embodiment 1
[0061] An interventional medical catheter with a marker, the catheter structure is a single-lumen tube, including a layer of tightly bonded marker layer and a contact layer, the marker layer is white, has photosensitivity, and has a photosensitive marker pattern, the pattern is black The contact layer is transparent, does not have photosensitivity, and has a light transmittance of 90%, and is a biocompatible polymer material layer. The inner diameter of the catheter is 0.8mm, the outer diameter is 1mm, and the length is 1m; the thickness ratio of the marking layer to the contact layer is 1:2.5.
[0062] The pattern of the marking layer, such as figure 1 As shown, it is used to measure the position and depth of catheter intervention.
[0063] The marking layer includes a photosensitizer with a mass fraction of 4%, and the photosensitizer is nano titanium dioxide particles. The particle size of the nano titanium dioxide particles is 0.2um. The marking layer also includes 20% ...
Embodiment 2
[0077] An interventional medical catheter with a mark, which is a 5-lumen tube, includes a tightly bonded marking layer and a contact layer, the marking layer is white, has photosensitivity, and has a photosensitive mark pattern, and the pattern is black; the contact layer The layer is transparent, does not have photosensitivity, and has a light transmittance of 80%, and is a biocompatible polymer material layer. The inner diameter of a single cavity in the 5-lumen tube is 0.3mm, 0.5mm, 1.0mm, 1.4mm, 1.6mm, the outer diameter of the entire multi-lumen tube is 3.6mm, and the length is 2m; the thickness ratio of the marking layer to the contact layer is 1:10.
[0078] The pattern of the marking layer is designed according to usage requirements.
[0079] The marking layer includes a photosensitizer with a mass fraction of 0.25%, and the photosensitizer is nano tin dioxide particles. The nano tin dioxide particles have a particle diameter of 0.5um. The marking layer also includ...
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