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Drug ball capsule and preparing method thereof

A balloon and drug technology, applied in the field of medical devices, can solve problems such as vascular restenosis and restrict the development of PCI, and achieve the effects of reducing loss, good adherence performance and better therapeutic effect

Pending Publication Date: 2017-12-29
SHANGHAI XINZHI MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After treatment, 5-60% of the patients will have vascular restenosis in the short and medium term, which seriously limits the development of PCI.

Method used

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  • Drug ball capsule and preparing method thereof
  • Drug ball capsule and preparing method thereof
  • Drug ball capsule and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Figure 1-3 A specific example of the drug balloon involved in the present invention is shown. in, figure 2 It shows a state when the drug balloon is not completely folded during the preparation process, and the protective layer is not covered on the drug layer at this time. In this embodiment, the drug balloon includes a balloon body 1 and a coating. The coating is divided into a protective layer 7 and a drug layer 2. The 360° surface of the balloon body 1 is covered with medicine. The balloon body 1 has three flaps 3 . The number of flaps 3 is not limited to three in the present invention. In the folded state, the medicine covered on the inner surface of the flap 3 is folded inside, so it does not contact the blood vessel wall, thus ensuring that this part of the medicine will not be lost when the balloon body 1 passes through the blood vessel. In the filled state, as image 3 As shown, the medicine covered on the inner surface of the flap 3 is exposed, and to...

Embodiment 2

[0072] Figure 4 Another drug balloon of the present invention is shown. In the inflated state, the cross section of the balloon body 1 shows that a depression 4 is provided between adjacent flaps. The function of the depression 4 is to make the drug balloon not completely block the blood flow even in the filling state, thereby prolonging the continuous filling time and providing more time for drug release, thereby achieving a better effect. The rest of the designs are the same as those in Embodiment 1, all of which cover the medicine at 360° and have flaps 3 . The number of recesses 4 is the same as the number of flaps 3 .

Embodiment 3

[0074] In the inflated state, the surface of the cross section of the balloon body is provided with depressions, which is beneficial to the passage of blood. Different from Embodiment 2, the depression is not limited to the depression between the flaps. All the other are with embodiment 2.

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Abstract

The invention discloses a drug ball capsule. The drug ball capsule includes a ball capsule body and a coating, wherein the coating includes a drug layer and a protective layer; the ball capsule body is covered with the drug layer, and the drug layer is covered with the protective layer which is used for preventing drugs on the drug layer from being washed away by blood. The invention further discloses a preparing method for the drug ball capsule. The drug ball capsule has the protective layer which can prevent the drugs from being washed away by blood so as to ensure that the drug ball capsule reaches a designated spot and then releases enough drugs to a site of action; the treatment effect is better, the production is convenient, no processes need to be added basically, and no additional production equipment is needed.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to a drug balloon and a preparation method thereof. Background technique [0002] Cardiovascular stenosis is one of the main causes of coronary heart disease. Percutaneous Coronary Intervention (PCI) is an important means of treating cardiovascular stenosis. With the increase in the number of stents used, the problem of in-stent restenosis (ISR) is becoming more and more serious. After treatment, 5-60% of the patients will have vascular restenosis in the short and medium term, which seriously limits the development of PCI. [0003] In recent years, a new technology to prevent restenosis of blood vessels after interventional therapy-drug balloons has emerged. It is to apply anti-intimal hyperplasia drugs on the surface of the balloon. When the balloon reaches the wall of the diseased vessel, it is stretched and filled, and contacts the intima of the vessel wall, and the drug is quic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M29/04A61M31/00A61L29/08A61L29/16
CPCA61L29/085A61L29/16A61M29/02A61M31/00A61L2300/608A61L2300/416A61M2210/12A61M2210/005A61M25/1002A61M25/104A61M2025/1004A61M2025/105
Inventor 盛卫文朱平
Owner SHANGHAI XINZHI MEDICAL TECH CO LTD
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