Pharmaceutical composition for treating esophageal cancer

A composition and drug technology, applied in the field of pharmaceutical composition for the treatment of esophageal cancer, can solve the problems of poor treatment effect of western medicine, achieve the effect of protection and disease resistance, improvement of disease resistance, and no toxic and side effects

Inactive Publication Date: 2018-05-11
TAISHAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment effect of western medicine is not good, and long-term use of western medicine has many side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 tablet

[0023] Weigh 11-15 parts of squid and octopus, 3-6 parts of centipede, 5-10 parts of scorpion, 3-5 parts of ginseng, 9-12 parts of yam, 5-8 parts of dried ginger, 9-15 parts of tangerine peel, and 8 parts of trichosanthes -10 parts, 5-9 parts of Danshen, 8-10 parts of Ophiopogon japonicus, 9-13 parts of Shougong, 3-7 parts of Zhebei, 3-7 parts of Pinellia japonica 5kg, Chuan Fritillaria 1kg, clipper grass 3kg , Eucommia 2kg, Shaxuan Fuhua 3kg, Sea Cuttlefish 2kg. Add water to extract 3 times, the amount of water added for the three times is 12 times, 8 times, and 6 times the total weight of the medicinal materials, and the extraction time for the three times is 3 hours, 2 hours, and 1 hour respectively. Combine the extracts, filter, and concentrate the filtrate to 70°C A clear paste with a relative density of 1.25 is added with auxiliary materials such as starch, ethanol and talcum powder to prepare tablets.

Embodiment 2

[0024] Example 2 tablet

[0025] Weigh 11-15 parts of squid and octopus, 3-6 parts of centipede, 5-10 parts of scorpion, 3-5 parts of ginseng, 9-12 parts of yam, 5-8 parts of dried ginger, 9-15 parts of tangerine peel, and 8 parts of trichosanthes -10 parts, 5-9 parts of Danshen, 8-10 parts of Ophiopogon japonicus, 9-13 parts of Shougong, 3-7 parts of Zhebei, 3-7 parts of Pinellia 40kg of Tongjingcao, 8kg of Chuan Fritillaria, 25kg of Scissors grass , Eucommia 20kg, Shaxuan Fuhua 25kg, Sea Cuttlefish 20kg. Reflux extraction with 40% ethanol for 3 times, the amount of ethanol each time is 10 times, 8 times, 4 times of the total amount of medicinal materials, the extraction time is 3 hours, 2 hours, 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated at 60 °C When the relative density is 1.25 extract, add auxiliary material starch, ethanol, talcum powder, make tablet.

Embodiment 3

[0026] Embodiment 3 granules

[0027] Weigh 11-15 parts of squid and octopus, 3-6 parts of centipede, 5-10 parts of scorpion, 3-5 parts of ginseng, 9-12 parts of yam, 5-8 parts of dried ginger, 9-15 parts of tangerine peel, and 8 parts of trichosanthes -10 parts, 5-9 parts of Danshen, 8-10 parts of Ophiopogon japonicus, 9-13 parts of Shougong, 3-7 parts of Zhebei, 3-7 parts of Pinellia Tongjingcao 15kg, Chuan Fritillaria 3kg, Scissors grass 13kg , Eucommia 8kg, Shaxuan Fuhua 13kg, Sea Cuttlefish 8kg. Add water to extract 3 times, the amount of water added for the three times is equivalent to 12 times, 8 times, and 6 times the total weight of the medicinal materials, and the extraction time is 3 hours, 2 hours, and 1 hour respectively. Combine the extracts, filter, and concentrate the filtrate to 70°C When the relative density is 1.20, add ethanol to make the alcohol content 40%, let it stand for 24 hours, filter, and concentrate the filtrate until the filtrate is concentrated...

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PUM

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Abstract

The application discloses a pharmaceutical composition for treating esophageal cancer. The pharmaceutical composition is an oral preparation prepared through the cooperation between Chinese medicinalmaterials and a pharmaceutically acceptable carrier. The Chinese medicinal materials are: cuttlebone, centipede, scorpion, ginseng root, common yam rhizome, dried ginger, tangerine peel, mongolian snakegourd root, danshen root, dwarf lilyturf tuber, house lizard, bulbus fritillariae thunbergii and pinellia tuber; and the parts by weight of the Chinese medicinal materials are: 11 to 15 parts of cuttlebone, 3 to 6 parts of centipede, 5 to 10 parts of scorpion, 3 to 5 parts of ginseng root, 9 to 12 parts of common yam rhizome, 5 to 8 parts of dried ginger, 9 to 15 parts of tangerine peel, 8 to 10parts of mongolian snakegourd root, 5 to 9 parts of danshen root, 8 to 10 parts of dwarf lilyturf tuber, 9 to 13 parts of house lizard, 3 to 7 parts of bulbus fritillariae thunbergii and 3 to 7 partsof pinellia tuber. While killing and inhibiting tumor cells, the pharmaceutical composition for treating esophageal cancer provided by the application can also enhance the immunity of the bodies of patients and the regulatory capability of the internal environment of the body and effectively protect and enhance the disease resistance of the body, thus increasing the long-term curative effect in treating esophageal cancer and the long-term survival rates of patients.

Description

technical field [0001] The application belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating esophageal cancer. Background technique [0002] Esophageal cancer refers to tumors that occur in the esophageal mucosa. It is one of the common tumors of the digestive tract. Its common symptoms are progressive dysphagia in patients. The early symptoms are usually not obvious. Sometimes they only feel discomfort when swallowing food. With the development of the disease, the obstructive state is aggravated, and malignant lesions may appear in the late stage. At present, western medicine has poor treatment effect, and long-term use of western medicine has many side effects. Therefore, there is a great demand for traditional Chinese medicines for the effective treatment of esophageal cancer. Contents of the invention [0003] In view of this, the technical problem to be solved in this application is to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P35/00A61K35/618A61K35/648A61K35/646A61K35/583
CPCA61K35/583A61K35/618A61K35/646A61K35/648A61K36/258A61K36/428A61K36/537A61K36/752A61K36/8888A61K36/8945A61K36/8966A61K36/8968A61K36/9068A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王涛
Owner TAISHAN MEDICAL UNIV
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