Built-in biological sleeve as well as preparation method and application thereof

A technology of physiological saline and water for injection, which is applied in the field of tissue engineering of biomedical materials, can solve the problems of undiscovered specific effects, different effects, complicated operations, etc., so as to prolong the ejaculation latency, reduce sensitivity, and improve the quality of sexual life. Effect

Active Publication Date: 2018-05-29
BEIJING JAYYALIFE BIOTECH CO LTD
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the middle of the 1980s, autologous fat injections began to be used to thicken the penis, but due to the different fat preparations, injection methods and injection volumes, the effects are also different, so the controversy is relatively large

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1 Preparation method of acellular allogeneic dermal matrix

[0070] Put allogeneic leather raw materials into 0.3g / L phospholipase and 0.1g / L trypsin solution, the pH value of the enzyme solution is 7.0, the temperature is 37°C, shake at 100rpm for 2 hours, replace the enzyme solution once, repeat this process once, The semi-finished product A is obtained; the phospholipase is a mixture of phospholipase A1: phospholipase A2: phospholipase C: phospholipase D according to the mass ratio of 1:1:1:1.

[0071] The semi-finished product A was taken out, put into a container filled with physiological saline solution, soaked in physiological saline, oscillated 3 times, each time for 2 hours, the oscillation speed was 80 rpm, and the temperature was 2°C to obtain the semi-finished product B.

[0072] Put the semi-finished product B into the solution containing 0.2g / LTritonX-100, 50KHz, 220W, ultrasonic for 5 minutes, soak for 3 hours, repeat this process 3 times, and get...

Embodiment 2

[0078] Example 2 Preparation method of acellular allogeneic dermal matrix

[0079] Put allogeneic leather raw materials into 0.2g / L phospholipase and 0.2g / L trypsin solution, the pH value of the enzyme solution is 7.0, the temperature is 37°C, shake at 100rpm for 2 hours, replace the enzyme solution once, repeat this process once, The semi-finished product A is obtained; the phospholipase is a mixture of phospholipase A1, phospholipase A2, phospholipase C and phospholipase D according to the mass ratio of 1:1:1:1.

[0080] The semi-finished product A was taken out, put into a container filled with physiological saline solution, soaked in physiological saline, oscillated 3 times, each time for 2 hours, the oscillation speed was 80 rpm, and the temperature was 2°C to obtain the semi-finished product B.

[0081] Put the semi-finished product B into a solution containing 0.2g / LSDS, 10mM EDTA, 50KHz, 220W, ultrasonic for 7 minutes, soak for 2 hours, repeat this process 3 times, and...

experiment example 1

[0089] Experimental example 1 Acellular allogeneic dermal matrix (built-in biological sleeve) used in dorsal nerve isolation surgery

[0090] Surgical method: After nerve block anesthesia at the root of the penis, the foreskin is circumcised for those with excessive prepuce, and for those who have undergone circumcision, a 3-5cm long skin incision is made along the original incision on the dorsal side of the penis. The superficial fascia and deep fascia were incised sequentially until the buffy membrane was fully exposed. Carefully separated to the coronary sulcus, the acellular allogeneic dermal matrix was prepared as required into a built-in biological sleeve and sutured and fixed on the buffy membrane, the distal end was to the coronal sulcus, and the urethra was not surrounded on both sides. The fascia and skin were sutured layer by layer. The penis is moderately pressurized and bandaged.

[0091] Postoperative treatment:

[0092] 1. The penis is moderately pressurized ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Suture strengthaaaaaaaaaa
Suture strengthaaaaaaaaaa
Suture strengthaaaaaaaaaa
Login to view more

Abstract

The invention relates to a built-in biological sleeve as well as a preparation method and application thereof. In order to provide a proper built-in biological sleeve material for a dorsal nerve isolation operation and a penile augmentation operation, the invention prepares a novel acellular allogenic dermis matrix material which is manufactured into a built-in biological sleeve; and the built-inbiological sleeve can be used for treatment of premature ejaculation and short penis. The acellular allogenic dermis matrix or the built-in biological sleeve is used for the dorsal nerve isolation operation and the penile augmentation or lengthening operation, and does not cut off dorsal nerves, so that psychological erectile dysfunction probability caused by worries of a patient about cutting offthe dorsal nerves is eliminated.

Description

technical field [0001] The invention belongs to the technical field of tissue engineering of biomedical materials, and in particular relates to a built-in biological cover and its preparation method and application. Background technique [0002] Premature ejaculation (PE, premature ejaculation) is one of the clinically common andrological diseases, and the incidence rate accounts for 14%-41% of adult males. It seriously affects the quality of sexual life, not only causes great harm to the body and mind of the majority of patients, but also threatens the relationship between husband and wife and family harmony. In the past, the cause of premature ejaculation was considered to be caused by mental and psychological factors, such as depression, high mental tension and other factors, but recent research results have shown that some premature ejaculation has neuropathic organic lesions, that is, hyperesthesia of the glans penis or sensory nerve excitement of the glans penis. Sex ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L27/36A61L27/50
CPCA61L27/3633A61L27/3687A61L27/3691A61L27/50A61L2430/32A61L2430/34A61L27/362A61L2430/40
Inventor 孙继煌王海曾昂白明张海林吴元翼张晓威王伟李雪银刘文进李卫强石清东
Owner BEIJING JAYYALIFE BIOTECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap