House dust mite allergy protein remover, and composition thereof

A technology of house dust mites and protein, applied in the directions of acaricides, biocides, animal repellents, etc., can solve the problem of not mentioning the allergy-inducing source of house dust mites, and achieve the effect of reducing the incidence rate

Inactive Publication Date: 2018-06-08
AYJ BIO LAB INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] However, the above-mentioned prior art only mentions the neutralization of excreta of dust mite as an allergy-inducing source, and does not mention allergy-inducing sources such as house dust mite itself or its dead body or partially dead body.

Method used

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  • House dust mite allergy protein remover, and composition thereof
  • House dust mite allergy protein remover, and composition thereof
  • House dust mite allergy protein remover, and composition thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0049]The killing effect of plant essential oils or steam distillates on D. americana was investigated by in-vapor bioassay. Briefly, 4050 adults (710 days old) each were inoculated on a circular cotton sheet at the bottom of a polystyrene container (diameter 5 cm, height 2 cm). Punch a hole with a diameter of 3 cm in the center of the container lid, place a fine wire mesh on it, and cover each container with a lid. After the reagent dissolved in 100 μl of ethanol was treated with a filter paper with a diameter of 5 cm, the filter paper was placed on a wire mesh, and a new lid was covered. The control area was only treated with 100 μl of ethanol. The insecticidal rate was investigated under a 20-fold dissecting microscope after 24 hours of treatment, and the mites that did not move when the wood with a pointed end touched the body or accessories were identified as dead mites.

[0050] Table 1 shows the results of the essential oils and steam distillates of the above-mentio...

experiment example 2

[0057] Regarding the killing effect of plant essential oils or steam distillates on American dust mite, the bioassay method in steam was used to investigate (0.17mg / cm 2 ), the results are shown in Table 2.

[0058] Table 2

[0059] [Table 2]

[0060]

[0061]

[0062]

experiment example 3

[0064] About the killing of dust mite by carrot seed essential oil formulation and peppermint essential oil formulation dissolved in polyoxyethylene + polyoxypropylene (9:1) styrenated phenyl ether [Ethanolpolyoxyethylene + polyoxypropylene (9:1) styrenated phenyl ether] solution The effect was investigated using spray bioassay.

[0065] The results are shown in Table 3 and Table 4 below, respectively.

[0066] Briefly, the test formulation was sprayed twice consecutively from a height of 10 cm onto a circular black cotton pad with a diameter of 5 cm and then dried for 5 minutes. After each round black cotton sheet that has been processed is placed on the bottom surface of a disposable bowl (diameter 5cm, high 1cm), each 4050 adults (710 days old) are inoculated on the black cotton sheet, and the bowl lid is covered. The spray of preferred d-phenothrin (d-phenothrin) or permethrin (permethrin cis: trans, 25:75) 2.5g / l spray as a positive control group as a commonly used kil...

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PUM

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Abstract

The invention relates to a house dust mite allergy protein remover, and a composition thereof, the remover: containing as the active ingredient, a natural plant-derived essential oil or a vapor distillate thereof; effectively removing house dust mite-derived allergens, so as to be used efficiently and in an environmentally-friendly manner, in preventing, reducing, alleviating or treating various allergic diseases capable of being caused by the allergens; and remarkably lowering the prevalence of various diseases caused by house dust mite and the incidence of exposure thereof to a normal person.

Description

technical field [0001] The present invention relates to a house dust mite allergic protein remover and a composition thereof, in particular to a house dust mite allergic protein remover derived from natural plant essential oils or steam distillates and a house dust mite allergic protein containing the remover. A composition for removing proteins or for killing house dust mites, wherein the remover effectively removes various allergic proteins derived from house dust mites by denaturing and neutralizing them, while maintaining the killing ability against house dust mites. Background technique [0002] The prevalence and severity of various allergic diseases such as asthma, atopic dermatitis, and rhinitis caused by house dust mites are the most serious public health problems worldwide [Arlian, L.G. 2002. Arthropod allergens and human health. Annu. Rev. Entomol .47, 395433; Bessor, J.C. & G. Pauli. 2011. Mite allergens: an overview. Eur. Ann. Allergy Clin. Immunol. 43:141156.]....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N65/42A01P7/02
CPCA01N65/00A01N27/00A01N31/02A01N31/04A01N31/08A01N31/16A01N35/02A01N35/04A01N35/06A01N43/08A01N43/30A01N47/46A01N49/00A01N65/06A01N65/42A01N65/44A01N65/10A01N65/22A01N65/28A01N65/36Y02A50/30
Inventor 高永律全光柱金贤敬H·伯鲁马尔萨米K·萨卡拉帕迪安安龙浚
Owner AYJ BIO LAB INC
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