Low-iron blood-supplementing agent, black fungus melanin active ingredient F1 and use of black fungus melanin active ingredient F1

Abstract

The invention discloses a low-iron blood-supplementing agent, a black fungus melanin active ingredient F1 and a use of the black fungus melanin active ingredient F1, and relates to the low-iron blood-supplementing agent, the black fungus melanin active ingredient F1 and the use of the black fungus melanin active ingredient F1. The problems that a conventional iron supplementing agent can cause diarrhea, constipation, maladjustment of intestinal flora, harm to gastrointestinal health, anaphylactic shock and other side effects, or is expensive, is limited in effect of anemia improvement and hasthe disease easy to relapse are solved. The preparation method of the black fungus melanin active ingredient F1 comprises the steps: one, dissolving black fungus melanin in a NaOH solution, and then loading the sample in a dextran gel column; and two, eluting with a PBS buffer solution, collecting an eluate at 34th-50th min, adjusting the pH value, allowing to stand, centrifuging, and carrying outvacuum freeze drying. The black fungus melanin active ingredient F1 can obviously improve the number of hemoglobin and haemocytes in an IDA mouse model, improves haemopoietic factors, increases ironabsorption, improves iron-deficiency anemia effectively, and also cannot cause nausea, abdominal pain, diarrhea, constipation and other adverse symptoms.

Description

technical field [0001] The invention relates to a low-iron blood-enriching agent, black fungus melanin active ingredients and uses thereof. Background technique [0002] Iron deficiency anemia (Iron Deficiency Anemia, IDA) is an anemia caused by the depletion of iron reserves in the human body resulting in decreased hemoglobin synthesis. This type of anemia is characterized by a lack of stainable iron in tissues such as bone marrow, liver, and spleen, and decreased serum iron, transferrin saturation, and ferritin. There are many causes of iron deficiency anemia, which are generally summarized as follows: (1) increased iron requirement, which mostly occurs in infants and pregnant women; (2) insufficient iron intake and malabsorption, resulting in insufficient iron intake. The reason is insufficient iron content in food, partial eclipse, phosphate, phytic acid, and tannic acid in vegetables, grains, and tea in food will reduce the absorption of iron in the gastrointestinal tr...

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to solve side effects such as nausea, abdominal pain, diarrhea, constipation, intestinal flora imbalance, harm to gastrointestinal health and other side effects caused by existing iron supplements, and greatly reduce the iron content in the medicine while maintaining at least equal blood enriching effect. Iron content, to prevent iron overload from affecting the immune response of the human body, and provide low-iron blood supplements, black fungus melanin active ingredient F1 and its use

Images