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High-throughput micro full-automatic DNA (deoxyribonucleic acid) synthesis equipment

A synthetic equipment and high-throughput technology, applied in the preparation of sugar derivatives, sugar derivatives, printing, etc., can solve the problems of complex post-processing process, low oligonucleotide chain flux, and large amount of chemical reagents. Achieve the effect of short time, small amount of chemical reagents, and high throughput

Inactive Publication Date: 2018-07-31
通用生物(安徽)股份有限公司
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AI Technical Summary

Problems solved by technology

The synthesis of oligonucleotide chains by this DNA synthesis equipment has the disadvantages of low flux, large amount of chemical reagents, high mutation rate, high cost, and complicated post-processing process, and the synthesized oligonucleotide chains can only be used as Primers for PCR amplification
Secondly, ordinary synthesizers cannot make primer libraries because the templates are fixed and not on glass slides

Method used

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  • High-throughput micro full-automatic DNA (deoxyribonucleic acid) synthesis equipment
  • High-throughput micro full-automatic DNA (deoxyribonucleic acid) synthesis equipment
  • High-throughput micro full-automatic DNA (deoxyribonucleic acid) synthesis equipment

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Embodiment Construction

[0022] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0023] see Figure 1-3 As shown, the high-throughput and micro-volume automatic DNA synthesis equipment includes gas-liquid control mechanism 1, piezoelectric nozzle printing mechanism 2, electrical control components 3, platform lifting mechanism 4, motion synthesis platform 5, high-throughput micro-volume sample adding and changing Liquid mechanism6.

[0024] The gas-liquid control mechanism 1 is used to provide basic reagents to the piezoelec...

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Abstract

The invention relates to DNA (deoxyribonucleic acid) synthesis equipment and particularly discloses high-throughput micro full-automatic DNA synthesis equipment. The high-throughput micro full-automatic DNA synthesis equipment comprises a gas-liquid control mechanism, a piezoelectric spray nozzle spray-printing mechanism, an electrical control assembly, a platform lifting mechanism, a motion synthesis platform, a high-throughput micro sampling liquid-exchanging mechanism. The high-throughput micro full-automatic DNA synthesis equipment uses a small amount of chemical reagent for synthesizing an oligonucleotide chain, uses short time, is flexible and varied, simple in finishing and high in synthesis throughput, and secondly, also provides a synthesis platform for production of a detection probe, a gene chip and a primer library.

Description

technical field [0001] The invention relates to a DNA synthesis device, in particular to a high-flux micro-quantity full-automatic DNA synthesis device. Background technique [0002] With the development of biology, human beings have gradually entered the era of actively rewriting biological gene information according to their own ideas from the era of passively reading biological gene (DNA) information, that is, artificially synthesized gene (DNA), artificially synthesized gene (DNA) Used in scientific research, medical testing, medicine, agriculture, industry and other fields. At present, the main method of artificially synthesizing genes (DNAs) is to splice and assemble oligonucleotide chains to obtain long-chain genes (DNAs) by chemical methods. The oligonucleotide chain is also processed by chemical methods with special equipment (ie: DNA synthesizer) to make up the four bases (ie: A, T, G, C) of the gene chain according to the artificially designed sequence. Link tog...

Claims

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Application Information

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IPC IPC(8): C07H21/04C07H1/00B41J2/01B41J3/00
CPCC07H21/04B41J2/01B41J3/00C07H1/00
Inventor 赵庆河刘宗文雍金贵
Owner 通用生物(安徽)股份有限公司
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