Component-compatible traditional Chinese medicine for preventing and treating Alzheimer disease
A technology of Alzheimer's disease and traditional Chinese medicine, applied in the field of traditional Chinese medicine research, can solve the problems of many components, adverse reactions and contraindications, and achieve the effect of reducing toxic effects, reducing drug dosage, and clear composition compatibility
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[0027] 1.0 Preparation of pharmaceutical ingredients
[0028] Ginseng total saponins: The extraction method is as follows, take the ginseng medicinal materials, cleanly select, cut into sections, add water and decoct twice, the first time is 2 hours, the second time is 1.5 hours, the decoction is filtered, and the filtrate is combined, and absorbed by D101 Resin column, eluted with water until colorless, then eluted with 60% ethanol, collect the 60% ethanol eluate, concentrate the filtrate to a clear paste with a relative density of 1.06~1.08 (80℃), dry at 100℃, and crush with 100 mesh , The finished product, total ginsenosides> 80% is put into storage, and the yield is 4%.
[0029] Coptis total alkaloids: The extraction method is as follows, take the Coptis medicinal material, cleanly select, crush to 12mm, add dilute sulfuric acid to heat and soak for extraction, add lime water and sodium chloride to alkalize the crystal, filter, add water to dissolve and adjust the pH value, add...
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