35results about How to "Reduce drug use" patented technology

The invention provides a feed additive for preventing a fatty liver of largemouth bass. The feed additive is prepared from the following raw materials in parts by weight: 15-22 parts of astragalus membranaceus, 13-20 parts of salviae miltiorrhizae, 4-8 parts of pericarpium citri reticulatae, 4-8 parts of fingered citron, 4-8 parts of citron, 7-12 parts of hawthorn, 3-6 parts of radix glycyrrhizae preparata, 5-8 parts of flos carthami, 4-6 parts of christina loosestrife herb, 4-6 parts of rheum officinale, 4-6 parts of herba artemisiae scopariae, 2-4 parts of curcuma aromatic, 4-8 parts of vitamin C, 3-5 parts of vitamin E, 3-6 parts of methionine and 1-3 parts of choline. The feed additive provided by the invention is capable of effectively preventing a fatty liver disease of the largemouth bass, so that frequent fatty liver phenomenon in a fish body when an artificial compound feed is used instead of fresh-frozen products in largemouth bass culture is solved; and an effective solving way is provided for healthy sustainable farming of the largemouth bass.

The invention discloses gastrodia elata forage for chickens and a preparation method thereof. The gastrodia elata forage is prepared from 480-500 weight parts of corn, 180-200 weight parts of soybean meal, 30-40 weight parts of pumpkin, 20-30 weight parts of rice bran, 20-30 weight parts of wheat bran, 10-15 weight parts of black sesame powder, 10-15 weight parts of black glutinous rice flour, 15-20 weight parts of black corn powder, 10-15 weight parts of black peanut powder, 50-70 weight parts of silkworm chrysalis powder, 25-30 weight parts of alfalfa, 5-10 weight parts of ginkgo leaf, 5-10 weight parts of gastrodia elata, 2-4 weight parts of ginseng, 8-11 weight parts of soybean paste and 4-5 weight parts of a phagostimulant. Through use of the Chinese herbal medicines such as gastrodia elata, the gastrodia elata forage improves chicken physique and reduces medicine use amounts. Through use of black sesame, palatability is improved, forage intake of chickens is improved and growth is accelerated. Through use of the gastrodia elata forage, a laying peak period of laying hens is effectively prolonged.

The invention discloses a method for ecologically breeding pelteobagrus fulvidraco. The method comprises the following steps: constructing an ecological floating bed, culturing in a planting barrel, stocking pelteobagrus fulvidraco fingerling, arranging the ecological floating bed, dynamically adjusting the floating bed, performing breeding management and the like. According to the method, arrangement and adjustment of the ecological floating bed are beneficial to maintaining the water temperature of a pond in a reasonable range and keeping the pond water to be clear, and an appropriate breeding water environment is produced to bred pelteobagrus fulvidraco. The pelteobagrus fulvidraco ingesting below the planted herba houttuyniae and the like is beneficial to improving the its immunity, and usage of medicines can be reduced. Besides fish catch, water spinach, herba houttuyniae and other economic crops can be harvested.

The invention discloses a method for extracting effective compositions from a composition of fructus ligustri lucidi and radix astragali through a supercritical extraction process and products thereof. The method comprises: crushing radix astragali and fructus ligustri lucidi and performing low-temperature drying, performing first extraction on radix astragali and fructus ligustri lucidi respectively or on a mixture of radix astragali and fructus ligustri lucidi by using supercritical carbon dioxide as an extracting agent, performing reduced-pressure evaporation and vacuum drying on the extracting liquid, so as to obtain a polyose-composition extracting product; performing secondary supercritical extraction on the first extraction residue, so as to obtain a flavonoid-composition extracting product; performing third supercritical extraction on the second extraction residue, so as to obtain a saponin-composition extracting product; and performing forth supercritical extraction on the thrid extraction residue, so as to obtain a terpene-composition extracting product The extraction method is capable of improving the extraction rate and the purity of the effective compositions in the composition of fructus ligustri lucidi and radix astragali, thereby reducing the dose of an astragalus membranaceus-ligustrum healthy-qi-reinforcing preparation and enabling the astragalus membranaceus-ligustrum healthy-qi-reinforcing preparation to have relatively good treatment effect.

The invention discloses a high-efficiency scanning and spraying method of whole plants of Allium fistulosum. The scanning spraying method is achieved through combination of a conventional power sprayer with a medicine switch, a spray main switch, a split-flow tee, double handles, double spray rods, double spray heads and other special spraying components, the spraying positions of the left-and-right two sets of spray heads can be changed, and the directions of nozzle holes of the spray heads can also be changed through rotation; and during spraying operation, the relative positions of the left-and-right two sets of spray heads are kept static, and are consistent with the advance direction of an operator, the advance trajectory of the spray heads is a straight line during the scanning spraying operation, and the static scanning spraying width is larger than the width of crop targets, so that efficient and precise scanning spraying is performed on three different agronomic-trait crops which include Allium fistulosum crops, tiled-type crops and low-cluster-type canopy plants. When the method is compared with commonly-used knapsack manual sprayers or knapsack electric sprayers, the work efficiency can be increased by 3 times or above, water can be saved by 60%, chemicals can be saved by 65%, and the control effect of pests and diseases can be improved by 8-33%; and moreover, the novel scanning spraying mode for the three types of crops which include Allium fistulosum is developed, and the level of the spraying technology and spraying devices of the three types of crops can be improved.

The invention relates to novel medicines and application, and particularly provides application of a composition of ginsenoside C-K and lamotrigine in preparation of anti-epilepsy medicines. Animal experiments prove that the composition of ginsenoside C-K and lamotrigine can be used for remarkably prolonging the incubation period of epilepsy, reducing the attack strength of epilepsy, shortening the duration of epilepsy and reducing the weight loss after attack, and indicate that the composition of ginsenoside C-K and lamotrigine can be used for relieving or controlling attack of epilepsy and inhibiting occurrence and development of epilepsy, and adverse medicine response caused by lamotrigine can be alleviated by reducing the dosage of lamotrigine.

The invention discloses a component-compatible traditional Chinese medicine for preventing and treating an Alzheimer disease. Raw material for extracts of traditional Chinese medicine effective components contains the following ingredients: ginseng or total saponins of panax ginseng; coptis chinensis or total alkaloids from coptis chinensis; and ligusticum wallichii or ligusticum wallichii alcoholextract. Compared with the original traditional Chinese medicine formula (Prepared polygonum multiflorum, ginseng, acorus gramineus, coptis chinensis and ligusticum wallichii), indexes of new compatibility of traditional Chinese medicine components in an animal behavior aspect and pathology change are better than those of compatibility of the original formula, and the new compatibility of the traditional Chinese medicine components has the same effects with the original formula in the aspect of controlling inflammation level; meanwhile, toxic effect and dosage of the original formula are reduced, the effective ingredients including ginsenoside, berberine and ligustrazine of the component-compatible traditional Chinese medicine are also clear and can achieve pharmacological effects by virtue of a blood brain barrier, the traditional Chinese medicine component compatibility accords with traditional Chinese medicine theory, the material basis for efficacy is clear, and characteristics ofthe modern traditional Chinese medicinal preparation are reflected, and therefore, the component-compatible traditional Chinese medicine disclosed by the invention is an ideal medicine for preventingand treating the Alzheimer disease.

The invention discloses a dry powder inhalant with lung cancer-resistant activity. The dry powder inhalant with the lung cancer-resistant activity comprises yuanhuacine and a lactose carrier, wherein the lactose carrier is prepared from rough lactose with the diameter being more than 110 microns and fine lactose with the diameter being 4 to 11 microns. According to the dry powder inhalant with the lung cancer-resistant activity, the yuanhuacine and the inhalable lactose are innovatively mixed to prepare the dry powder inhalant for treating lung cancer, the medicine is directly given to a target part locally and accurately, the concentration of the medicine at the target point is increased, the toxic and side effects of other tissues are reduced and the curative effect is improved. An optimal prescription process is screened out by using a new-generation medicinal impactor to simulate a pulmonary administration method, so that more medicines are settled in the lung, an in-situ administration effect is achieved, and the lung tissue targeting aim is fulfilled. The dry powder inhalant with the lung cancer-resistant activity can obviously increase the concentration of the medicines in the lung tissue, improve the curative effect of treating the lung cancer, reduce the distribution of the medicines in the heart, liver, spleen, kidney, brain and reproductive system and reduce the toxicity on other tissues.

The invention belongs to the technical field of medicine, and particularly relates to a flos lonicerae-herba artemisiae-fructus gardeniae extract, a preparation method thereof and application of the flos lonicerae-herba artemisiae-fructus gardeniae extract to preparation of anti-Coxsackievirus A6 medicines. Antiviral experiment results show that the petroleum ether part, the ethyl acetate part andthe n-butyl alcohol part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract have high anti-CV-A6 activity; Fractions H and J of the petroleum ether part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract have high anti-CV-A6 activity; the fraction E of the ethyl acetate part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract has good anti-CV-A6 activity. and 30% alcohol and 60% alcohol elution products of the n-butyl alcohol part of the flos lonicerae-herba artemisiae-fructus gardeniae alcohol extract have high anti-Coxsackievirus A6 activity.

The invention discloses a noise collecting system device for a sewage plant blower. The noise collecting system device is composed of three parts, namely a sound collecting zone, a sound guiding zone and a sound dividing zone, wherein the sound collecting zone comprises a reflecting shield, a sound collecting shield, a shrinking section, a sound binding section which is used during noise binding of a plurality of blowers, and the like; the sound guiding zone is composed of a straight line sound guiding pipe and an elbow; the sound dividing zone comprises a sound dividing shield, a sound dividing pipe, a sound dividing hole and the like; moreover, a noise reduction layer is arranged outside the whole collecting system. The noise collecting system device can fully collect and guide the blower noise, can reduce noise energy loss as much as possible, can facilitate full utilization of high energy of noise, and has a wide development space and market prospect.

The invention provides a medicine composition for treating chronic nephritis. The medicine composition is a pellet prepared from the following raw materials and accessory in parts by weight: Chinese medicine herb raw materials: 4,166 parts of lespedeza virgata, 750 parts of radix scutellariae, 1,000 parts of folium pyrrosiae and 1,000 parts of radix astragali; and accessory: 39-98 parts of filler, wherein the filler is one of starch, soluble starch and dextrin or the mixture of more than two thereof. The invention also provides a preparation method of the medicine composition. In the invention, according to the physicochemical characteristics of the raw material extract of 'Shenyansiwei tablets', the raw materials are prepared into pellets and then encapsulated, thus relatively large drug loading capacity is ensured, and the problem that the medicine can not be prepared into hard capsules on the premise of reducing the dose of the patent medicine of the original dosage form is solved; and meanwhile, in the preparation process of pellets, by observing the pill forming method, the type of adhesive and wetting agent and the drying method, the dosage of the accessory and the drying time are further reduced, the production cost is effectively saved, and industrial production is possible.

The invention relates to a health-care feed for improving the compactness of grass carp in breeding period and preparation method thereof, and belongs to the technical field of fish feed production. The feed comprises the following raw materials: 5-25 parts of soybean meal, 8-30 parts of rapeseed meal, 3-10 parts of fermented rapeseed meal, 5-15 parts of cottonseed meal, 3-10 parts of domestic DDGS, 3-10 parts of imported DDGS, 5-15 parts of rice bran, 5-15 parts of flour, 5-12 parts of corn starch, 2-5 parts of soybean oil, 1-3 parts of potassium dihydrogen phosphate, 1-2.5 parts of bentonite, 0.05-0.3 part of lysine hydrochloride at 98.5%, 0.05-0.1 part of choline chloride, 0.3-0.8 part of vitamin premix, 0.5-1.5 parts of mineral premixes, 0.01-0.05 part of an antioxidant and 0.1-0.15 part of a mildew preventive. The products can enable the immune function of the grass carps to be the best, improve the disease resistance of the grass carps, avoid the looseness and falling of the grass carp scales when the grass carps are centrally caught in the market, at the same time does not improve the feed costs, and thus can enhance the comprehensive culture benefits of farmers.

The invention discloses a green Chinese onion multi-line scanning and spraying component. A power sprayer is matched with a special spraying component, scanning and spraying are implemented by multi-group stereoscopic clamp spraying of the left side and the right side of a green Chinese onion line, the positions of two groups (or more than two groups) of spray nozzles are kept still during spraying operation and consistent with the advancing direction of an operator, and the advancing track of the spray nozzles for scanning and spraying operation is overlapped with the center line of the straight or curved green Chinese onion line. Spray rods can adopt thickened and lengthened structures, the number of vertical rods, vertical rod tees, left spray nozzles and right spray nozzles can be matched with that of green Chinese onion lines needing simultaneous scanning, the total length of the spray rods reaches 20-30 meters, and the spray rods are fixed to the back of a suspended drag sprayingmachine in a suspended manner. According to the scanning and spraying component, water and pesticides are saved, pesticide droplet spraying uniformity and target hitting rate are improved, environmental pollution and waste caused by the pesticides are reduced, and the component can be applied to hilly farmlands in southern hilly regions and can also be applied to northern flat plain farmlands.

The invention provides a mixed culture method for fishes and macrobrachium nipponense. The method comprises the following steps: firstly disinfecting a macrobrachium nipponense pond, cultivating macrobrachium nipponense larvae through mating of male and female macrobrachium nipponense, throwing the macrobrachium nipponense larvae from the middle ten days of the July to the middle ten days of the August, throwing fry from the September to the October, and performing feeding and culture. According to the invention, the method takes full advantage of idle production resources, does not need to increase professional equipment, has no culture pollution, employs industrialized management personnel and normative culture technical standards, applies a biological agent to control water quality, reduces the use amount of drugs, makes the macrobrachium nipponense meet pollution-free and healthy requirements, and improves product quality value. In addition, the high-quality macrobrachium nipponense larvae obtained after hybridization can exert heterosis, and has obvious improvement in aspects such as improvement of a growth speed and disease and stress resistant ability and delaying of sexualmaturity than macrobrachium nipponense larvae obtained by cultivation of traditional local macrobrachium nipponense parents.

The invention relates to a bactericidal composition containing picoxystrobin and metrafenone. A weight ratio of active ingredients, namely picoxystrobin and metrafenone, is preferably (1-40):(40-1), further perferably (1-20):(20-1); and the bactericidal composition comprises 1-85% by mass of the active ingredients and the balance of auxiliary ingredients allowed to be used and accepted in pesticides. A dosage form of the bactericidal composition is a water dispersible granule, wettable powder, a suspending agent, aqueous emulsion, microemulsion and the like, and the bactericidal composition ismainly used for preventing and controlling wheat scab and wheat powdery mildew.

The invention discloses a method for preparing catalpol and a derivative thereof based on radix rehmanniae praeparata and application, and belongs to the technical field of medicines. According to themethod, the catalpol derivative is prepared by reacting a caffeic imide compound with the catalpol in anhydrous acetonitrile, wherein the caffeic imide compound is obtained by reacting caffeic acid with amino acids; and the amino acids include serine and threonine. The catalpol derivative obtained by the method has a blood sugar reducing effect, and the dosage of the catalpol derivative is smallwhile the same blood sugar reducing effect is achieved; moreover, the catalpol derivative has no toxicity to cells, and does not influence cell proliferation; moreover, the catalpol derivative has theeffect of improving the activity of tyrosinase, so that the activity of the tyrosinase at least reaches 140%; and the catalpol derivative also has a good analgesic effect, and the minimum mechanicalretraction threshold value reaches 35g.

The invention provides a method for effectively extracting genomic DNA (deoxyribonucleic acid) of melaleuca alternifolia, which comprises the following steps: (1) grinding a sample into powder by liquid nitrogen, transferring the powder to a centrifuge tube, adding a DNA extraction buffer which is conventionally preheated, uniformly mixing and carrying out water bath at 65 DEG C for 30 minutes; (2) taking out the centrifuge tube and cooling to room temperature, adding a mixed solution of chloroform and isoamyl alcohol, uniformly mixing and performing centrifugal separation; (3) taking supernate, adding chloroform, uniformly mixing and performing centrifugal separation; (4) taking supernate, adding absolute ethyl alcohol which is conventionally precooled, uniformly mixing, standing for 30 minutes at -20 DEG C, then performing centrifugal separation, and discarding the supernate; (5) washing sedimentation with ethyl alcohol of which the volume concentration is 75%, drying at room temperature and adding a DNA dissolution buffer, and storing at -20 DEG C for standby use. The method provided by the invention is capable of effectively and rapidly extracting the genomic DNA of the melaleuca alternifolia which is high in purity and suitable for PCR detection, and the use of toxic chemicals in the extracting process is reduced.

The invention discloses an automatic pesticide spraying control method and device for fruit tree pest control, and relates to the technical field of pest control. According to the technical scheme, the method is characterized by comprising the steps as follows: recognizing the insect pest category according to image information, and carrying out the statistics of the distribution probability; screening insect pests exceeding a set value as a first preparation category according to the distribution probability; collecting soil physical and chemical property information, and determining a priority value of the insect pest category according to a matching degree between the suitable growth range and the soil physical and chemical property information; screening out the insect pest category with the priority value exceeding an early warning value as a second preparation category; if the insect pest category only belongs to the first preparation category, carrying out upward rotary spraying of pesticide on the target object; if the insect pest category only belongs to the second preparation category, carrying out downward rotary spraying of the pesticide on the target object; and if the insect pest category belongs to the first preparation category and the second preparation category at the same time, carrying out upward and downward rotary spraying of pesticide on the target object. According to the invention, the source of insect pest categories can be visually reflected, so that the pesticide spraying device is flexibly controlled to carry out adaptive pesticide control.

The invention relates to a method for extracting a saponins component from Yixinshu composition by a supercritical fluid extraction method and a product thereof, and specifically relates to pulverizing ginseng, radix Ophiopogonis, fructus Schisandrae Chinensis, radix astragali, radix Salviae Miltiorrhizae, rhizoma Ligustici Chuanxiong and fructus crataegi to 0.3-2.0 mm in prescription amount, drying at low temperature, extracting separately or mixing. The saponins in Yixinshu preparation were extracted with supercritical carbon dioxide as extractant, which provided saponins effective ingredients for the development of new preparation.

The invention belongs to the technical field of medicine, and specifically discloses construction and applications of an anti-influenza-virus or anti-inflammatory drug screening model based on in vitro culture of human lung particles. According to the invention, lung tissue is cut into small particles with a size of 0.05-0.2 mm<3>, the small particles are uniformly sub-packaged in the form of a suspension, and the sub-packaged small particles are infected with influenza virus after in vitro culture is performed for a certain time; the experiment results prove that influenza virus can replicateefficiently in pig lung particle tissue and human lung particle tissue, and initiate the up-regulation of a series of inflammatory factors, and the known anti-influenza-virus drugs and the known anti-inflammatory drugs can inhibit influenza virus and inflammatory factors in the constructed lung particle tissue models and have dose effects; the construction method has characteristics of simple andrapid operation, time saving and labor saving, and the constructed model can substantially retain the tissue activity and reduce the waste of tissue, and is close to the physiological conditions of animals; and after the method is optimized, the anti-influenza virus or anti-inflammatory drug screening model can achieve the micro, rapid and uniform effect, and can accurately evaluate drugs.