18 results about "Metrafenone" patented technology

The application provides a synthesis process of metrafenone, in which inorganic alkali KOH is used as a catalyst, a key intermediate 4-(((5,5-dimethyl-dihydroisoxazole-4-yl)thio)methyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol can be obtained at low production cost and high yield, metrafenone is prepared through substitution reaction and oxidation reaction, the reaction yield is high, raw materials are simple and easy to obtain, three-waste emissions are small, and the process is beneficial to industrial mass production.

The utility model discloses a pyroxasulfone production waste liquid recovery treatment device, which particularly relates to the field of waste liquid treatment and comprises a treatment tank, a water inlet is arranged on one side of the top of the treatment tank, a filter plate is arranged above the inner wall of the treatment tank, and a stirring shaft is connected to the center of the inner wall of the top of the treatment tank through a bearing. A servo motor is connected to the center of the top of the treatment tank, an arc-shaped cleaning brush is connected to the outer wall of the top of the stirring shaft, the bottom end of the arc-shaped cleaning brush abuts against the filter plate, and the outer wall of the upper portion of the treatment tank is sleeved with a waste collecting box. The servo motor drives the stirring shaft to rotate, the stirring shaft rotates to drive the arc-shaped cleaning brush to rotate, the arc-shaped cleaning brush rotates to clean the filter plate to avoid blockage, and meanwhile, due to the fact that the arc-shaped cleaning brush is arc-shaped, solid impurities can be pushed to the discharging opening in the edge of the filter plate and then discharged into the waste collecting box to be collected. And centralized taking out for recycling and the like is facilitated.

The present application belongs to the field of pesticides, and particularly relates to a ternary herbicidal composition containing fluazychlorid and application thereof. The ternary herbicidal composition comprises a herbicidal effective amount of active ingredient A, active ingredient B and active ingredient C, wherein the active ingredient A is fluazychlorid; the active ingredient B is selected from one of the following compounds: fluroxypyr-methyl, cyprosulfamide or florasulam; and the active ingredient C is selected from one of the following compounds: metrafenone or chlorotoluron. The composition can effectively prevent and remove various weed problems such as weeds of gramineae and broadleaf weeds, and has the characteristics of expanding the herbicidal spectrum, reducing the application amount, being able to produce a synergistic effect and solving the problem of resistant weeds.

The invention relates to the technical field of chemical synthesis, and particularly discloses a synthesis method of a pyroxasulfone key intermediate. According to the synthesis process of the pyroxasulfone key intermediate, provided by the invention, 4-chloromethyl-5-difluoromethoxy-1-methyl-3-trifluoromethyl-1H-pyrazole with high yield and high purity is prepared by taking an acidic material as a catalyst and taking cheap dichloroethane as a reaction solvent, the content of condensation impurities is controlled to be 0.5%-1%, and the yield is controlled to be 0.5%-1%. The product yield can reach 96%-98%, raw materials are easy to obtain, operation steps are simple, process conditions are mild, product aftertreatment is simple, and the method is suitable for large-scale industrial production and has very important significance on sustainable development of pyroxasulfone pesticides.

This invention belongs to the field of pesticide technology, specifically relating to a pesticide composition containing benzimidazole. The pesticide composition's active ingredient is a compound of benzimidazole and fluazinam or emodin methyl ether. This invention, through indoor bioactivity tests, found that the compound of benzimidazole with fluazinam or emodin methyl ether, within a certain mass ratio range, has a synergistic effect against various plant fungal diseases such as Rhizoctonia solani, Curvularia crescentis, and Sclerotium sclerotiorum, helping to improve control efficacy. This is of great significance for the research and development of pesticides for controlling diseases such as cucumber damping-off, corn curvularia leaf spot, and peanut white mold.

The invention provides a continuous synthesis method of pyroxasulfone. According to the process, an alkaline system, especially a phosphate system, is adopted to replace traditional strong acid reaction media such as sulfuric acid and trifluoroacetic acid, corrosion of strong acid to equipment is thoroughly avoided, the equipment investment cost is greatly reduced, and the use amount of hydrogen peroxide or the concentration of hydrogen peroxide or additional addition of a transition metal catalyst does not need to be increased; the pyroxasulfone product with high yield and high purity can be obtained, the reaction time is greatly shortened, and the reaction efficiency is remarkably improved; in addition, the concentration of hydrogen peroxide is controlled at a lower level in the whole continuous reaction and oxidation reaction process, the reaction risk is reduced, the reaction time is short, few impurities are generated, the post-treatment method is simple and convenient, the operability is high, and the industrial practical value is very good.

The application discloses a preparation method of metrafenone, which comprises the following steps: (1) reacting 5,5-dimethyl-4,5-dihydroisoxazole-3-sulfonyl chloride under the action of a sulfite to obtain 5,5-dimethyl-4,5-dihydroisoxazole-3-sulfinate; (2) reacting the 5,5-dimethyl-4,5-dihydroisoxazole-3-sulfinate with a pyrazole intermediate 3 to obtain the metrafenone; wherein, a general structure of the pyrazole intermediate 3 is as follows: Y is halogen, or the application provides a new route for synthesizing metrafenone, avoids using hydrogen peroxide, meta-chloro peroxide benzoic acid, ozone and other oxidants to prepare the metrafenone in a traditional route, greatly reduces the production risk, improves process safety, and is suitable for large-scale industrial production.

The application provides a metal peroxide complex molecule catalyst and a preparation method and application thereof, and a continuous synthesis method of metrafenone. The metal peroxide complex molecule catalyst is prepared through a series of operation steps, transition metal ion centers, organic ligands and metal-peroxide bridge (M-O-O-M) structures are introduced into the prepared metal peroxide complex molecule catalyst, and the prepared metal peroxide complex molecule catalyst is used for oxidizing sulfide into sulfone under the synergistic effect between the above structures, and has excellent selectivity and catalytic efficiency. Especially, the metal peroxide complex molecule catalyst is used for catalyzing 3-[(5-difluoromethoxy-1-methyl-3-trifluoromethylpyrazol-4-yl)-methylthio]-4,5-dihydro-5,5-dimethyl-1,2-isoxazole to oxidize and synthesize metrafenone, the reaction efficiency, selectivity and safety of the oxidation reaction can be effectively improved, and therefore the preparation cost of metrafenone is further reduced.

This application relates to a fungicide composition containing tetraflufenazole and benomyl, the composition comprising: (a) a liquid tetraflufenazole active ingredient at room temperature; (b) a solid benomyl active ingredient at room temperature; (c) a [2,4,6-tris(1-phenylethyl)phenyl] ether polymerized from ethylene oxide and propylene oxide; and (d) an optional functional surfactant. The [2,4,6-tris(1-phenylethyl)phenyl] ether polymerized from ethylene oxide and propylene oxide effectively solves the storage compatibility problem between the two different forms of tetraflufenazole and benomyl, especially addressing the issue of mutual aggregation and sedimentation between the oil droplet form of tetraflufenazole and the particulate form of benomyl during dilution after storage, reducing the risk of sprayer clogging. The fungicide composition of this application effectively solves the compatibility problem between the liquid tetraflufenazole active ingredient and the solid benomyl, and the prepared product exhibits good performance in storage stability.

The application provides a synthesis method of metrafenone, and belongs to the technical field of organic synthesis, and comprises the following steps: firstly, subjecting 5-hydroxy-1-methyl-3-(trifluoromethyl)-1H-pyrazole to a hydroxymethylation reaction to obtain 4-(hydroxymethyl)-5-hydroxy-1-methyl-3-(trifluoromethyl)-1H-pyrazole; then, reacting with difluorobromoacetic acid to obtain 4-(hydroxymethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole; then, subjecting to a mesylation reaction to obtain a mesylate intermediate; simultaneously, preparing 3-acetylthio-5,5-dimethyl-4,5-dihydroisoxazole from 3-chloro-5,5-dimethyl-4,5-dihydroisoxazole; then, subjecting the intermediate to a thioetherization reaction with the mesylate intermediate to obtain a thioether coupling intermediate; finally, performing an oxidation reaction in the presence of a catalyst to obtain metrafenone. By adopting the mesylate activated intermediate and combining a continuous flow fixed bed oxidation process, the method is favorable for improving the purity and total yield of the target product and reducing the tungsten residue in the product.

The application discloses a preparation method of metrafenone. The method comprises the following steps: taking an isoxazole compound as a raw material, coupling with SO2 under the action of formate and a nickel catalyst to obtain an intermediate, and then performing a substitution reaction on the intermediate under alkaline conditions to obtain metrafenone. The method has the advantages of mild reaction condition, high yield, less waste, no dangerous reaction such as oxidation, low cost, high safety, and suitability for industrial production.

The invention belongs to the technical field of herbicides, and particularly relates to an efficient weeding composition for airport lawn broadleaf weeds and application thereof.The efficient weeding composition is prepared from carfentrazone-ethyl, chipton sodium, fluroxypyr-mepthyl and 2, 4-D isooctyl ester as main effective components, by matching with a special auxiliary agent composed of xanthan gum, polyethylene glycol and the like and a pesticide application method matched with an airport scene, efficient prevention and control of rumex plicata broadleaf weed plants are achieved, and the weeding composition is safe, free of phytotoxicity and low in soil residue on common airport turfgrass such as cynodon dactylon, bluegrass, agrostis pilosa and festuca arundinacea. The device can cut off a grass-insect-bird ecological chain of an airport, remarkably reduces the bird strike risk, is suitable for lawns of various airport flying areas, and has extremely high popularization value.

The application provides a novel preparation method of metrafenone. The preparation method provided by the application has the advantages of high reaction yield, high product purity, mild reaction condition, short reaction time, short reaction route, easy availability of raw materials, low cost, good safety, no need of using chlorinating reagents, less generation of three wastes, good environmental friendliness, and suitability for green large-scale production.

The application discloses a synthesis method of metrafenone. The method uses raw material A and air as raw materials, and an oxidation reaction is carried out under the catalysis of a Fe(III) catalyst to obtain metrafenone. The method has mild reaction conditions, high yield, less waste, avoids the reaction of hydrogen peroxide and storage, is low in cost, and is suitable for industrial production.

The application relates to the technical field of organic synthesis, and discloses a method for synthesizing metrafenone. The method comprises the following steps: feeding a solution of a compound of formula II and a first oxidant into a micro-channel reactor to perform a first reaction, so as to obtain a solution containing a compound of formula III; feeding the solution containing the compound of formula III and a second oxidant into a tubular reactor to perform a second reaction, so as to obtain a compound of formula I. The micro-channel reactor and the tubular reactor which can realize intensified mixing are connected in series to realize continuous flow reaction, the compound of formula II is oxidized into the compound of formula I, and the speed, yield, purity and safety of the oxidation reaction are improved.

The invention relates to the field of organic synthesis, and particularly provides a preparation method of pyroxasulfone, which is characterized in that the reaction can be carried out at normal temperature by using quaternary ammonium hydrogen peroxysulfate as a catalyst and an oxidant, the yield is high, no transition metal is needed, the reaction time is short, the content of the reaction intermediate sulfoxide is controlled, and the reaction cost is reduced.

The application belongs to the technical field of pesticide fungicidal technology, and discloses a use of a fungicidal composition containing benzoic enofluoroquinazolinone for preventing and treating citrus anthracnose, wherein the fungicidal composition comprises active ingredient A and active ingredient B; the active ingredient A is benzoic enofluoroquinazolinone; the active ingredient B is prochloraz or a salt thereof; and the mass ratio of the active ingredient A to the active ingredient B is 40:1-1:50. The fungicidal composition has obvious synergistic effect for preventing and treating citrus anthracnose, can effectively control the spread and development of the disease, reduces the use amount of pesticides, is safe to crops, and is friendly to the environment.

Provided is a method for more effectively controlling weeds in soil treated with metrafenone. The present invention relates to a method for controlling weeds by treating soil composed of clay having a content of less than 15% and sand having a content of 65% or more with metrafenone in the form of columnar crystals, and the like.