Traditional Chinese medicine prescription for treating ovarian insufficiency

A technology of ovarian function and traditional Chinese medicine, which is applied in pharmaceutical formulas, drug combinations, unknown raw materials, etc., to restore ovarian function, adjust menstrual cycle and menstrual volume, and improve menstrual conditions.

Inactive Publication Date: 2018-10-12
THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Family history of breast cancer or breast hyperplasia, uterine fibroids, etc. are contraindications for HRT. Because of the above-mentioned side effects, some scholars have suggested that HRT is only suitable for POI patients over 51 years old (close to the normal menopausal age)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The traditional Chinese medicine prescription for the treatment of ovarian insufficiency in this embodiment is a basic formula composed of 12 traditional Chinese medicines, and the raw materials of Chinese medicines are weighed according to the following proportions by weight:

[0039] 9 parts of Bupleurum, 10 parts of Angelica, 6 parts of Chuanxiong, 10 parts of Paeoniae Alba, 10 parts of Rehmannia glutinosa, 10 parts of Codonopsis pilosula, 9 parts of Atractylodes macrocephala, 10 parts of Poria cocos, 10 parts of antler gum, 12 parts of Achyranthes bidentata, 10 parts of Cyperus cyperi, Chenpi 6 parts.

[0040] First, take the raw materials of traditional Chinese medicine according to the weight ratio mentioned above, soak them in water, put them in a multifunctional extraction tank and extract them for 1 to 3 times, each extraction for 1 to 3 hours, filter, combine each filtrate, and concentrate to 1.0g About crude drug / ml. Then, it can be prepared into any pharmac...

Embodiment 2

[0042] The present embodiment treats the traditional Chinese medicine prescription of ovarian insufficiency (POI), according to the following proportioning by weight, Chinese medicine raw material is weighed according to the prescription of deficiency of kidney essence:

[0043] 9 parts of Bupleurum, 10 parts of Angelica, 6 parts of Rhizoma Chuanxiong, 10 parts of Paeoniae Alba, 15 parts of Rehmannia glutinosa, 15 parts of Codonopsis pilosula, 9 parts of Atractylodes macrocephala, 10 parts of Poria cocos, 15 parts of antler gum, 12 parts of Achyranthes bidentata, 10 parts of Cyperus cyperi, 6 parts of tangerine peel, 15 parts of epimedium, 15 parts of Morinda officinalis, 15 parts of dodder.

[0044] The preparation method is the same as in Example 1.

[0045] Zhao, female, 33 years old, went to see a doctor because of "infertility for 4 years". The patient has not been pregnant since she got married 4 years ago and was trying to conceive. Ovarian function examination showed ...

Embodiment 3

[0047] A traditional Chinese medicine prescription for the treatment of ovarian insufficiency (POI), which is formulated for syndromes of phlegm-damp accumulation type

[0048] Take by weighing Chinese medicine raw material by following proportioning by weight:

[0049] 6 parts of Bupleurum, 5 parts of Angelica, 3 parts of Chuanxiong, 5 parts of Radix Paeoniae Alba, 5 parts of Rehmannia glutinosa, 15 parts of Codonopsis, 12 parts of Atractylodes macrocephala, 15 parts of Poria cocos, 5 parts of antler gum, 6 parts of Achyranthes bidentata, 10 parts of Cyperus cyperi, 6 parts of tangerine peel, 12 parts of French pinellia.

[0050] The preparation method is the same as in Example 1.

[0051] Sun, female, 42 years old, went to see a doctor because of "repeated delayed menstruation and less menstruation for 3 years". The patient is obese, weighing 70kg, height 160cm, BMI: 27.3kg / m 2 . The complexion is paler, the movement is slower, the speech speed is slower, the body feels ...

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Abstract

The invention discloses a traditional Chinese medicine prescription for treating ovarian insufficiency. The prescription is prepared from ,by weight,6-12 parts of radix bupleuri,5-15 parts of angelicasinensis,3-9 parts of rhizoma chuanxiong,5-15 parts of radix paeoniae alba,5-15 parts of prepared rhizome of rehmannia,5-15 parts of radix codcnopsitis pilosulas,6-12 parts of rhizoma atractylodis macrocephalae,5-15 parts of poria,5-15 parts of deer-horn glue,5-15 parts of radix cyathulae,5-15 parts of rhizoma cyperi and 3-6 parts of dried orange peel. The traditional Chinese medicine prescription has ingenious and refined compatibility, and clinical application proves that the traditional Chinese medicine prescription can effectively improve the ovarian sex hormone level, recover the ovarianfunction to a certain extent, improve the natural pregnancy rate of a patient, and improve the hectic fever sweating, palpitation, dysphoria, insomnia and other perimenopause syndromes of a POI patient; the prescription has wide clinic promotion prospects, is prepared into various dosage forms of Chinese patent medicine and is more convenient for patients; the total cost is low, so that the economic burden of such patients can be greatly reduced, and the medical burden of the country can be reduced to a certain extent.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine and specifically refers to a traditional Chinese medicine prescription for treating ovarian insufficiency (POI). Background technique [0002] Premature ovary insufficiency (POI) refers to women who have established regular menstruation, before the age of 40, persistent amenorrhea and reproductive organ atrophy due to ovarian function decline, often accompanied by increased gonadotropin levels and decreased estrogen , the clinical manifestations are amenorrhea, infertility, varying degrees of hot flashes, hyperhidrosis, vaginal dryness, mood swings, dizziness, insomnia, and decreased libido, which are similar to menopausal symptoms of low ovarian function. The incidence rate is 1-2%, and the cause of the disease has not been fully clarified. 90% of the cases are idiopathic, and 10% are related to autoimmunity, infection, gene and iatrogenic. POI has great long-term harm, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P15/08A61K35/32A61K35/36A61K35/586
CPCA61K35/32A61K35/36A61K35/586A61K36/076A61K36/21A61K36/232A61K36/233A61K36/236A61K36/284A61K36/296A61K36/344A61K36/39A61K36/43A61K36/65A61K36/71A61K36/746A61K36/752A61K36/804A61K36/8888A61K36/8905A61P15/08A61K2300/00
Inventor 杨玉彬李琼
Owner THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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