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Polypeptide composition for preventing and improving striae gravidarum

A polypeptide composition and the technology of the composition are applied in the directions of skin care preparations, medical preparations containing active ingredients, cosmetics, etc., and can solve problems such as human harm

Pending Publication Date: 2018-11-30
SHENZHEN WINKEY MEDICAL RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods have inherent defects and are potentially harmful to the human body. The research on the treatment of stretch marks still needs to be further explored.

Method used

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  • Polypeptide composition for preventing and improving striae gravidarum
  • Polypeptide composition for preventing and improving striae gravidarum
  • Polypeptide composition for preventing and improving striae gravidarum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Prescription (1kg essence)

[0027]

[0028] Preparation method:

[0029] Add the formulated amount of sodium hyaluronate into the water, stir to make the mixture uniform, then heat to 80-85°C, keep warm and stir to make it disperse evenly. When the temperature drops below 40°C, add glycerin, aloe vera gel, palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, ceramide 3, caprylyl glycol and 1,2-hexanediol, and stir evenly. Adjust the pH of the solution to about 5.5 with 15% triethanolamine.

Embodiment 2

[0031] Prescription (1kg essence)

[0032]

[0033] Preparation method:

[0034] Add the formulated amount of sodium hyaluronate into the water, stir to make the mixture uniform, then heat to 80-85°C, keep warm and stir to make it disperse evenly. When the temperature drops below 40°C, add glycerin, aloe vera gel, palmitoyl tripeptide-5, hexapeptide-9, palmitoyl tetrapeptide-7, ceramide 3, caprylyl glycol and 1,2-hexanediol, and stir well. Adjust the pH of the solution to about 5.5 with 15% triethanolamine.

Embodiment 3

[0036] Prescription (1kg essence)

[0037]

[0038]

[0039] Preparation method:

[0040] Add the formulated amount of sodium hyaluronate into the water, stir to make the mixture uniform, then heat to 80-85°C, keep warm and stir to make it disperse evenly. When the temperature drops below 40°C, add glycerin, aloe vera gel, palmitoyl tripeptide-5, hexapeptide-9, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, ceramide 3, caprylyl glycol and 1,2-hexanedi Alcohol, stir well. Adjust the pH of the solution to about 5.5 with 15% triethanolamine.

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PUM

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Abstract

The invention discloses a polypeptide composition for preventing and improving striae gravidarum. The composition contains one, two or three polypeptides of a polypeptide for promoting collagen synthesis and promoting epithelial regeneration, a polypeptide for supplementing fibronectin and a polypeptide for promoting elastin synthesis, and one or two polypeptides of a polypeptide for reducing inflammatory response and tightening the skin and a polypeptide for delaying skin aging and raising defensive power of the skin. The polypeptide composition of the invention is safe to human body, has noirritating or toxic or side effect, can repair epidermis, basilar membrane and dermis of the skin, diminish inflammation, promote growth of connective tissues and increase generation of collagen and elastin, and can be used for antenatal prevention and postnatal repair of striae gravidarum.

Description

technical field [0001] The invention belongs to the technical field of biomedical polypeptide drugs and provides a polypeptide composition for preventing and improving stretch marks. Background technique [0002] Stretch marks (striae gravidarum) are a type of atrophic striae, which occur during pregnancy and are mainly manifested as atrophic cord-like skin changes on the abdomen, chest, lower back, buttocks and thighs. The early symptoms are dark red or purple stripes of different widths and lengths, followed by depigmentation, atrophy, and finally a white or silver linear skin lesion after stabilization. The occurrence of stretch marks and its difficult-to-eliminate symptoms have caused great psychological burden and stress to patients, and greatly affected their quality of life. [0003] At present, the cause and mechanism of stretch marks need to be further studied. It is generally accepted that the occurrence of stretch marks is the result of endocrine factors leading ...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61Q19/08
CPCA61K8/64A61K2800/5922A61Q19/08
Inventor 丁文锋
Owner SHENZHEN WINKEY MEDICAL RES DEV
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