A kind of laxative granule

A laxative and granule technology, applied in the direction of drug combination, plant/algae/fungus/moss ingredients, oil/fat/wax non-effective ingredients, etc., can solve problems such as ineffectiveness and dependence

Active Publication Date: 2021-07-06
WUHAN MAYINGLONG MASSIVE HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

People with chronic habitual constipation who use medicines containing rhubarb, aloe or senna for a long time will develop dependence, and as the dosage increases, it will eventually become ineffective

Method used

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  • A kind of laxative granule
  • A kind of laxative granule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 The influence of different traditional Chinese medicine prescriptions on mouse defecation function

[0021] The Chinese medicine prescription of embodiment 1-10 sees the following table 1.

[0022] Table 1 Traditional Chinese Medicine Prescription Form (g)

[0023]

[0024]

[0025] Get the traditional Chinese medicine prescription of embodiment 1-10, grind into fine powder standby, as test sample.

[0026] 144 adult male ICR mice, weighing 18-22 g, were randomly divided into 12 groups (groups of Examples 1-10, blank group, and model group), with 12 mice in each group. Example 1-10 groups were administered by intragastric administration at a dose of 6.5 g / kg, and the blank control group and the model control group were intragastrically administered with distilled water for 15 consecutive days.

[0027] After 15 days, mice in each group were fasted without water for 24 hours. The blank group was given distilled water, and the model group and 10 test...

Embodiment 11

[0033] Hemp seed 15Kg, Huai Mi 12Kg, Luo Han Guo 5Kg, wolfberry 8Kg, tangerine peel 10Kg, chrysanthemum chrysanthemum 5Kg, bamboo leaves 9Kg, hawthorn 3Kg, resistant dextrin 3Kg, maltitol 8Kg, inulin 6Kg, scented tea extract 2Kg.

[0034] 1) Take Hemp Seed, Huai Mi, Luo Han Guo, Lycium barbarum, Tangerine Peel, Hangbai Chrysanthemum, Bamboo Leaf, and Hawthorn, add 6 times the weight of water, decoct and extract twice, each time for 2 hours, and collect the extract after filtration (total 850Kg) ;

[0035] 2) Add a complex enzyme consisting of 10.2Kg cellulase, 4.25Kg pectinase, 4.25Kg amylase and 2.55Kg neutral protease to the extract, enzymolyze it at 45°C for 3 hours, then heat and boil for 15 minutes Inactivating the enzyme, concentrating the enzymolysis solution under reduced pressure into a clear paste with a relative density of 1.1;

[0036] 3) Add absolute ethanol to the clear paste to make the weight content of ethanol reach 65%, stir and let stand overnight;

[0037...

Embodiment 12

[0040] Raw material prescription is identical with embodiment 11.

[0041] 1) Take Hemp Seed, Huai Mi, Luo Han Guo, Lycium barbarum, Tangerine Peel, Chrysanthemum Chrysanthemi, Bamboo Leaf, and Hawthorn, add 12 times the weight of water to decoct and extract once for 3 hours, and collect the extract after filtration (total 900Kg);

[0042] 2) Add a compound enzyme consisting of 13.5Kg cellulase, 2.7Kg pectinase, 2.7Kg amylase and 4.5Kg neutral protease to the extract, enzymolyze it at 60°C for 1 hour, then heat and boil to make the enzyme Inactivation, the enzymolysis solution is concentrated under reduced pressure into a clear paste with a relative density of 1.05;

[0043] 3) adding dehydrated ethanol to the clear ointment to make the weight content of ethanol reach 40%, and leave it to stand overnight after stirring;

[0044]4) Take the supernatant after alcohol precipitation, concentrate under reduced pressure into a thick paste with a relative density of 1.25; take resis...

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Abstract

The invention discloses a laxative granule, which is composed of hemp seed, pagoda japonica, Luo Han Guo, wolfberry, tangerine peel, chrysanthemum chrysanthemum, light bamboo leaf, hawthorn, resistant dextrin, maltitol, inulin, scented tea extract and other raw materials. The Chinese herbal medicines selected in the present invention are based on tonifying and secreting. They do not contain anthraquinone substances, and the effect is more moderate, and will not stimulate the intestinal mucosa, which not only prevents the occurrence of colon melanoma, but also does not produce Dependence, no recurrence after drug withdrawal. Therefore the present invention is a kind of definite curative effect, safe and reliable laxative traditional Chinese medicine.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a granule for moistening intestines and laxatives. Background technique [0002] With the acceleration of the pace of life, changes in eating habits, and the influence of social and psychological factors, the incidence of constipation in my country is getting higher and higher, and it is increasing year by year. Constipation occurs at all ages. Although it does not directly threaten people's lives, it has a great impact on people's lives and work. Constipation has many hazards. It can not only aggravate the primary disease, but also induce cardiovascular and cerebrovascular diseases, leading to colon cancer, senile dementia, and memory loss. [0003] Rhubarb, aloe vera, senna leaves, cassia seeds, etc. are mostly used in the laxative traditional Chinese medicine or health food ingredients in the market. Such powerful laxatives containing anthraquinones can stimulate th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/16A61K47/40A61K47/36A61K47/26A61K47/44A61P1/10
CPCA61K9/1623A61K9/1652A61K9/1664A61K36/287A61K36/42A61K36/489A61K36/60A61K36/734A61K36/752A61K36/815A61K36/899A61K2236/19A61K2236/331A61K2236/51A61K2236/55A61P1/10A61K2300/00
Inventor 苏光祥周道年孙金龙刘莉鲁青陈雅芬王玉巧
Owner WUHAN MAYINGLONG MASSIVE HEALTH CO LTD
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