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Preparation method and application of traditional Chinese medicine composition and Chinese medicine extract

A technology of extracts and compositions, applied in the field of health care products, can solve problems such as no treatment, cardiovascular and cerebrovascular diseases endangering physical health, etc., and achieve the effect of reducing total cholesterol

Active Publication Date: 2021-09-17
GUANGZHOU SHENNONG BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Cardiovascular and cerebrovascular diseases seriously endanger people's health, but at present there is no drug that has a good curative effect on cardiovascular and cerebrovascular diseases such as hyperlipidemia and lipemia

Method used

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  • Preparation method and application of traditional Chinese medicine composition and Chinese medicine extract
  • Preparation method and application of traditional Chinese medicine composition and Chinese medicine extract
  • Preparation method and application of traditional Chinese medicine composition and Chinese medicine extract

Examples

Experimental program
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preparation example Construction

[0071] The present invention also provides a preparation method of the Chinese medicine extract, comprising extracting 1-9 parts by weight of Danshen medicinal material, 1-3 parts by weight of American ginseng medicinal material, and 1-3 weight parts of Panax notoginseng medicinal material to obtain the extract and then mixing 0.2-1.2 The step of mixing the earthworm extract in parts by weight. The Danshen medicinal material, the American ginseng medicinal material, and the Sanqi medicinal material can be extracted by heating and refluxing respectively, and the specific steps of the reflux extraction include: taking the Danshen medicinal material, the American ginseng medicinal material or the Sanqi medicinal material and heating them in an alcohol solvent Reflux, filter, collect the filtrate, concentrate to obtain the extract of alcohol extraction; collect the filter residue and add water to decoct, filter, collect the filtrate, concentrate to obtain the extract; mix the extra...

Embodiment 1

[0078] Preparation of earthworm extract: Prepare 4kg of fresh earthworm, wash it with clean water first, soak it with 0.9% normal saline for 4 hours, change the water every 1 hour, let it spit out the dirt in the stomach, drain the water, The dry weight is 825g, adding water 10 times the weight of earthworm by weight for ultrasonic extraction, filtering the extract, and spray drying to obtain 205g of dry matter, which is earthworm extract. The earthworm extract used in the subsequent comparative examples is the earthworm extract prepared in this example.

[0079]Preparation of Danshen, American ginseng and Panax notoginseng extracts: take Danshen medicinal materials, American ginseng medicinal materials, and Sanqi medicinal materials to screen, remove impurities, and then slice the medicinal materials, then weigh 300g of Danshen medicinal materials, 100g of American ginseng medicinal materials and 100g of Sanqi medicinal materials to obtain a mixture, Use 8 times the weight of...

Embodiment 2

[0082] Preparation of Earthworm extract: Take 50 g of Earthworm medicinal material, add 10 times the weight of Earthworm in water for ultrasonic extraction, filter the extract, and spray dry to obtain 12.5 g of Earthworm extract.

[0083] Preparation of extracts of Danshen, American ginseng, and Panax notoginseng: take Danshen medicinal materials, American ginseng medicinal materials, and Sanqi medicinal materials to screen, remove impurities, then slice the medicinal materials, and then weigh 100g of Danshen medicinal materials, 100g of American ginseng medicinal materials, and 100g of Sanqi medicinal materials to obtain a mixture , with 8 times the weight of the mixture of ethanol (concentration is 95%) heating and reflux extraction for 1 hour, filtered, and the filtrate was recovered under reduced pressure to an alcohol extraction extract with a relative density of 0.93 for subsequent use. The filtered residue was decocted with 10 times the weight of water for 0.5h, filtered...

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Abstract

The invention relates to a Chinese medicine composition, a preparation method and an application of a Chinese medicine extract. The composition of the earthworm extract in parts by weight, the preparation method of the Chinese medicine extract comprises taking 1-9 parts by weight of Salvia miltiorrhiza, 1-3 parts by weight of American ginseng, and 1-3 parts by weight of Panax notoginseng, extracting to obtain the extract, and then mixing with The step of mixing 0.2‑1.2 parts by weight of the earthworm extract, the present invention finds through a large number of comparative experiments that the extract obtained by using salvia miltiorrhiza, American ginseng, notoginseng and earthworm extracts uses a lower dose than the extract obtained from other traditional Chinese medicine ingredients. , medium dose or high dose all have a very significant therapeutic effect on hyperlipidemia models, and can effectively and significantly reduce total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL‑C) in plasma.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a preparation method of a Chinese medicine composition, a Chinese medicine extract and an application thereof. Background technique [0002] Cardiovascular and cerebrovascular diseases are collectively referred to as cardiovascular and cerebrovascular diseases. Blood or bleeding disorders. Cardiovascular and cerebrovascular disease is a common disease that seriously threatens human health. It has the characteristics of high prevalence, high disability rate and high mortality rate. Even if the most advanced and perfect treatment methods are applied, more than 50% of the Survivors of cerebrovascular accidents cannot take care of themselves completely. The number of people who die from cardiovascular and cerebrovascular diseases in the world is as high as 15 million every year, ranking first among all causes of death. Cardiovascular and cerebrovascular diseases are al...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537A61P3/06A23L33/105A61K35/62
CPCA61K35/62A61K36/258A61K36/537A61K2236/333A23L33/105A61P3/06A61K2300/00
Inventor 李莹雪丁韵芸陈嘉慧李乾坤黄静贤李紫薇
Owner GUANGZHOU SHENNONG BIOLOGICAL TECH
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