Dry type fluorescence immunoassay instrument

A fluorescent immunoassay and dry technology, which is applied in the field of dry immunofluorescence analyzers, achieves the effects of simple operation, high precision and rapid detection.

Inactive Publication Date: 2019-02-05
HEBEI GENSURE BIOTECH LIC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of the above-mentioned shortcomings of the prior art, the purpose of the present invention is to provide a dry fluorescent immunoassay analyzer, which is used to solve the problem in the prior art that lacks an instrument for accurate quantitative detection of fluorescent chromatography test paper

Method used

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  • Dry type fluorescence immunoassay instrument
  • Dry type fluorescence immunoassay instrument
  • Dry type fluorescence immunoassay instrument

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1 Appearance

[0070] To the outward appearance of a kind of dry-type fluorescent immunoassay instrument prepared in the present invention, observe with normal or corrected visual acuity and check with feel, find that its outward appearance is flat, without edge, burr; Each adjustment button, button and switch all can work normally, The connector of the connection line should be in good contact; the reader should work normally, and the digital display should be clear and complete.

Embodiment 2

[0071] Example 2 Repeatability

[0072] Repeatability is the degree of agreement between the results of the same sample measured in parallel several times.

[0073] Requirements: The coefficient of variation (CV) of repeated measurements of the instrument is less than or equal to 5%.

[0074] Method: Take C3 and C5 quality control cards as test samples, repeat the test 10 times, and the coefficient of variation (CV) should be less than 5%.

[0075]

[0076] In the formula:

[0077] S = standard deviation of sample test value

[0078] = Average value of sample test values.

[0079] The test results are shown in Tables 1 and 2.

[0080] Table 1: Table of repeatability test results

[0081]

[0082] Table 2: Result display

[0083]

[0084] The results of the repeatability test show that the CV values ​​of the detection repeatability of the fluorescent quality control cards of each concentration of the instrument are far less than 5%, which meets th...

Embodiment 3

[0085] Example 3 Linearity

[0086] Linearity refers to the degree of linear correlation between the calibration value and the measured value of different concentrations.

[0087] Requirements: Use fluorescent quality control cards with different fluorescein concentrations in 5 gradients of C2, C3, C4, C5, and C6 as test samples, measure once each, and compare the actual measured value with the corresponding set of calibration values ​​X , Calculate the linear regression coefficient a (slope) and b (intercept) with the linear regression analysis method, and then calculate the regression value Y#=aX+b, and its linear correlation coefficient R≥0.99. Composition of quality control products: P1 is 20mg / L positive quality control product of CRP, C1-C6 fluorescent quality control cards, the results are shown in Table 3.

[0088] table 3

[0089] serial number

Composition and preparation

quantity

P1

20mg / L CRP

0.5ml / piece

C1

0pmol / ml fluores...

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Abstract

The invention provides a dry type fluorescence immunoassay instrument which comprises a barcode scanning module, an optical detecting module, a motor transmission module, a storage processing module,a control module and a display module. The invention further provides a using method of the dry type fluorescence immunoassay instrument. The dry type fluorescence immunoassay instrument meets the urgent requirement of current test paper factories to precise and quantitative detection of fluorescence chromatography test paper, is easy and convenient to operate, small in size and portable, and canbe widely applied to a plurality of fields of disease detection, medical health care, epidemic surveillance, food inspection and quarantine and the like.

Description

technical field [0001] The invention belongs to the technical field of analysis and detection equipment, and relates to a dry fluorescence immunoassay analyzer. Background technique [0002] With the rapid development of immunoassay technology, whether it is the prediction of disease outbreaks (SARS, bird flu, etc.), the detection of toxic and harmful substances in food (clenbuterol, etc.) Reagents are developed in the direction of so-called point-of-care testing (POCT), which is quick to detect, easy to operate, and the results are available "on the spot". POCT is a rapid detection and analysis technology, which has the advantages of rapid detection, low cost and high efficiency. In recent years, the POCT (rapid diagnosis) system has been widely used in clinical practice due to its advantages of simplicity, speed and low cost, and has become an important development direction and the fastest growing field of the in vitro diagnostic (IVD) industry. Due to a series of advan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/58G01N33/68G01N21/64
CPCG01N21/6428G01N33/582G01N33/68G01N2333/4737
Inventor 丁晓辉
Owner HEBEI GENSURE BIOTECH LIC
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