Fractionation selection tool in radiotherapy planning

A technique for planning, selecting inputs, applied in the field of fractionated radiation therapy, oncology

Active Publication Date: 2019-03-15
KONINKLJIJKE PHILIPS NV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in current clinical practice, fractionated regimens are often not optimally chosen, so often they do not balance differential effects in an optimal manner

Method used

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  • Fractionation selection tool in radiotherapy planning
  • Fractionation selection tool in radiotherapy planning
  • Fractionation selection tool in radiotherapy planning

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] reference figure 1 , Describes the radiation therapy planning equipment or system. A medical imaging device 10, such as a computed tomography (CT) or magnetic resonance (MR) scanner, acquires one or more images of a subject, including at least the tumor to be irradiated and possibly one or more organs at risk (OAR) Surrounding tissues. These images are often called planning images because they are used in planning radiation treatments. To this end, an outline drawing graphical user interface (GUI) 12 is implemented on the computer 14. The computer 14 has a display 16 and one or more user input devices (such as a keyboard 18 and / or a mouse 19 and / or a touch-sensitive overlay of the display part 16). 物). The contour drawing graphic GUI 12 enables skilled users (e.g., physicians, dosimeters, etc.) to describe features in the planning image, including the tumor to be irradiated and any OAR near the tumor (or more generally, this will be used in any treatment In the path o...

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Abstract

Fractionation optimization receives inputs including a radiation dose distribution to be delivered by fractionated radiation therapy, maximum and minimum number of fractions, and Biologically Effective Dose (BED) constraints for one or more organs-at-risk. A two-dimensional (2D) graph is displayed of a parameter X equal to or proportional to (I) versus a parameter Y equal to or proportional to (II) where N is the number of fractions, D is a total radiation dose to be delivered by the fractionated radiation therapy, and d t is the fractional dose in fraction t. A constraint BED lines are displayed on the 2D graph depicting each BED constraint. A marker is displayed at a location on the 2D graph defined by a current fractionation and a current total dose. A new value for the current fractionation and/or the current total dose is received, and the marker is updated accordingly. Alternatively a second marker is displayed showing the new fractionation scheme along with its comparative advantages and disadvantages with respect to the current fractionation.

Description

Technical field [0001] The following generally involves the field of fractionated radiation therapy, fractionated radiation therapy planning, oncology, and related fields. Background technique [0002] In radiation therapy, the therapeutic dose of radiation is usually delivered to the patient within several radiation treatments, and a recovery period of one day is usually scheduled between successive segments. This method is called fractional radiation therapy. The main idea behind fractionated delivery is to expect a worse recovery of tumor tissue from the segmented dose compared to healthy tissue, so fractionated delivery allows for a larger overall therapeutic dose. Therefore, increased doses in more segments can achieve better tumor control, however, this gain must always be balanced with the probability of normal tissue complications. [0003] Both the positive killing effect of radiation on tumors and its negative damaging effect on healthy organs are affected by the fracti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1031A61N5/1045A61N5/1039G16H20/40G16H15/00A61N2005/1074A61N2005/1087G06F3/0484A61N5/1071G16H40/60G16H30/00
Inventor Z·佩尔科J·翁克尔巴赫M·F·巴尔
Owner KONINKLJIJKE PHILIPS NV
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