Dose-guided self-adaptive radiotherapy planning re-optimization system and method

A radiation therapy and re-optimization technology, applied in radiation therapy, X-ray/γ-ray/particle irradiation therapy, treatment, etc., can solve the problems of not considering the difference between the dose received by the patient and the expected dose, and the inability to ensure the optimality of the plan.

Active Publication Date: 2019-03-26
ANHUI UNIVERSITY
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Problems solved by technology

[0005] At present, the re-optimization of adaptive radiotherapy plans is mostly based on changes in the patient's anatomical structure. Simple manual adjustments or partial optimization based on opt

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  • Dose-guided self-adaptive radiotherapy planning re-optimization system and method
  • Dose-guided self-adaptive radiotherapy planning re-optimization system and method
  • Dose-guided self-adaptive radiotherapy planning re-optimization system and method

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Embodiment

[0026] S10. Import the reference image, anatomical structure, plan and dose information of the research object according to the international radiotherapy data transmission standard.

[0027] Wherein, the reference image is the initial scan CT image of the research object or the positioning image of the previous treatment before the current treatment (such as the CBCT image obtained from the image-guided positioning device). The anatomical structure is the contour information of the tumor target area and the organs at risk delineated by the doctor on the original CT image with the help of the radiotherapy planning software. The reference plan is based on the original CT image and anatomical structure, with the help of the radiotherapy planning software to make a plan that meets the doctor's treatment requirements, including the field angle, the subfield shape and weight at each angle, and the dose information is the dose distribution, including organ Dose Volume Histogram DVH....

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Abstract

The invention discloses a dose-guided self-adaptive radiotherapy planning re-optimization system and method. The system includes a guide module, a data processing module, a plan re-optimization judgment module and a plan re-optimization module. The guide module is used for guiding the reference image, anatomical structure, planning and dose information of a research object, and an image for guiding precise positioning during current fractional treatment; the data processing module is used for calculating the anatomical structure of the current image and the anatomical structure of a referenceimage; the plan re-optimization judgment module is used for judging whether to enter the plan re-optimization module or not according to the anatomical structure change, the actual dose received by patients is compared with the planned dose if the anatomical structure change is within the threshold, re-optimization is needed if there are great difference between the actual dose and the planned dose, otherwise, an original reference plan is used as the current treatment plan. The plan re-optimization not only considers the difference between the current anatomical structure and the original anatomical structure, but also uses the fast conjugate gradient algorithm to automatically optimize the plan according to the actual dose received by the research object.

Description

technical field [0001] The invention relates to a plan re-optimization system and method in dose-guided adaptive radiotherapy, through which an optimized plan suitable for the current image can be obtained. Background technique [0002] With the development of tumor radiotherapy technology, problems caused by organ movement and deformation during treatment have become more and more prominent. The whole treatment process of tumor radiotherapy lasts about a month, and it is divided into multiple treatments. The position and shape of the organs have been changing between the treatment sessions, which are no longer consistent with those before the treatment. If the same plan is always used, it will definitely affect the The effect of the treatment. [0003] In order to solve this problem, adaptive radiation therapy (Adaptive Radiation Therapy, ART) technology has received more and more attention and research. Any technology that adjusts the treatment process through feedback c...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/1038A61N5/1039
Inventor 曹瑞芬李国丽
Owner ANHUI UNIVERSITY
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