Angstrom silver oral liquid and preparation method and application in gastric cancer treatment thereof

A technology of Amiyin oral liquid and Miyin oral liquid, which is applied in the field of medicine, can solve the problems of affecting the quality of life of cancer patients, the inability to balance treatment and quality of life, and the side effects of palliative treatment for advanced patients, etc., and achieve the ability to inhibit proliferation and migration , The process is green and environmentally friendly, and the process is simple

Inactive Publication Date: 2019-04-16
SHENZHEN AMCAN MEDICAL BIOTECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned treatment methods generally need to remove part or even all of the stomach, and postoperative chemotherapy will seriously affect the quality of life of cancer patients
The side effects of palliative treatment for advanced patients are also large, and the treatment and quality of life cannot be taken into account. Therefore, it is still urgent to find a new efficient and non-toxic drug in the field of gastric cancer treatment.

Method used

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  • Angstrom silver oral liquid and preparation method and application in gastric cancer treatment thereof
  • Angstrom silver oral liquid and preparation method and application in gastric cancer treatment thereof
  • Angstrom silver oral liquid and preparation method and application in gastric cancer treatment thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] This embodiment provides a kind of angstrom silver oral liquid, which can be used to treat gastric cancer, and it contains the following ingredients: angstrom level elemental silver powder: 1.0g / L; medicinal sucrose: 100.0g / L; high-purity distilled water: 899.0g / L.

[0024] Angstrom silver material is an emerging Angstrom technology in recent years. It uses physical or chemical methods to make elemental silver and other silver-containing compounds into Angstrom-level metal powder, and the particle size is mostly below 100 Angstrom. So it is called Amy silver. The acquisition process is roughly as follows: input metal wires below a certain size into the explosion chamber and use high-voltage ionization blasting, then ventilate to collect metal vapor, and use the ventilation system to send it to the buffer zone for cooling, degaussing, ultrasonic dispersion, cyclone wind separation and classification collection The powder is stored in the storage tank, and then inert ga...

Embodiment 2

[0032] The difference between this embodiment and Example 1 is that the angstrom silver oral liquid contains the following concentrations of ingredients: angstrom level elemental silver powder: 0.8g / L; medicinal sucrose: 80.0g / L; high-purity distilled water: 919.2 g / L, the specific preparation steps are as follows:

[0033] Step 1, adding the spherical angstrom level elemental silver powder with a particle diameter of 25Ang into high-purity distilled water to obtain a spherical angstrom level silver powder solution whose concentration of the spherical angstrom level elemental silver powder is 0.8g / L;

[0034] Step 2, using ultrasonic equipment to disperse the spherical Angstrom silver solution in step 1, controlling the ultrasonic power to be 15KW, the frequency to be 50KHz, and the dispersion time to be 60s;

[0035] Step 3, add medicinal sucrose to the spherical angstrom silver solution after step 2 disperses, control the concentration of medicinal sucrose to be 80g / L, then ...

Embodiment 3

[0038] The difference between this embodiment and Example 1 is that the angstrom silver oral liquid contains the following concentrations of ingredients: angstrom level elemental silver powder: 0.5g / L; medicinal sucrose: 50.0g / L; high-purity distilled water: 949.5 g / L, the specific preparation steps are as follows:

[0039] Step 1, adding the spherical angstrom level elemental silver powder with a particle diameter of 10Ang into high-purity distilled water to obtain a spherical angstrom level silver powder solution whose concentration of the spherical angstrom level elemental silver powder is 0.5g / L;

[0040] Step 2, use ultrasonic equipment to disperse the spherical angstrom silver solution in step 1, control the ultrasonic power to 8KW, the frequency is 50KHz, and the dispersion time is 60s;

[0041] Step 3, adding medicinal sucrose to the spherical angstrom silver solution dispersed in step 2, controlling the concentration of medicinal sucrose to be 50g / L, then using ultras...

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Abstract

The invention discloses angstrom silver oral liquid and a preparation method and application in gastric cancer treatment thereof. The angstrom silver oral liquid is prepared from angstrom silver element powder, medicinal sugar and high-purity distilled water. The preparation method comprises the steps that the angstrom silver element powder is added to the high-purity distilled water to obtain anangstrom silver solution; dispersing treatment is conducted on the angstrom silver solution; the medicinal sugar is added to the dispersed angstrom silver solution, and dispersing treatment is conducted again; the dispersed angstrom silver solution is heated and sterilized, and the angstrom silver oral liquid is obtained after natural cooling is conducted. Angstrom silver injection has significantgastric cancer cell proliferation and migration inhibition capability. The appearance and weight of primary organs are not significantly changed after oral consecutive application of angstrom silveris conducted for 15 days, and H&E dyeing and immunohistochemical analysis prove that the expression amount of tissues structures and activated Caspase-3 of the primary organs after angstrom silver application is conducted is not significantly changed.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to an Amisil oral liquid used for inhibiting gastric cancer cells and promoting tissue repair, a preparation method thereof and its application in treating gastric cancer. Background technique [0002] In the past two decades, the incidence and mortality of gastric cancer in Asia (especially China, South Korea, and Japan) have been increasing year by year, and are significantly higher than those in Europe and the United States. Moreover, the incidence of gastric cancer ranks fourth in the incidence of cancer in the world, and the mortality rate ranks second, which seriously threatens human health. my country is a country with a high incidence of gastric cancer. The number of cases and deaths of gastric cancer accounted for 42.6% and 45.0% of the global gastric cancer incidence and death respectively, ranking fifth in incidence and sixth in mortality among 183 countries in the world. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/38A61K9/08A61P35/00
CPCA61K9/0053A61K33/38A61K47/26A61P35/00
Inventor 司徒伟怡谢辉王杨范荣王振兴
Owner SHENZHEN AMCAN MEDICAL BIOTECH LTD
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