39results about How to "Mild side effects" patented technology

This invention provides methods for alleviating seizure disorders in an animal, particularly epilepsy, by regulating the flux through the gluconeogenic enzyme PEPCK in brain cells.

This invention provides methods for alleviating paroxysmal disorders in an animal, particularly epilepsy, by modulating glycolysis in brain cells.

This invention provides methods for alleviating paroxysmal disorders in an animal, particularly epilepsy, by modulating glycolysis in brain cells.

The present invention relates to the new use of high solubility berberine in preparing medicine. The high solubility berberine may be dissolved in 500 times of water and is easy to be absorbed by human body to make best use and raise curative effect. It may be used in treating and preventing hypertension, hyperlipemia, arrhythmia, heart disease, hepatitis, etc.

A compound medicine containing kurarinol, prostaglandic E1 and aspirin is prepared through including the kurarinol and prostaglandin E1 by 6-0-malto-beta-cyclodextrin, mixing, adding others, and preparing the freeze dried powder injection. It can be used for treating cancers, cardiovascular and cerebrovascular diseases and hepatitis. Its advantages are sure curative effect, and no toxic by-effect.

The invention relates to the technical field of drugs and provides an application of nicotinamide to preparation of drugs or health products for healing diabetic wounds. Nicotinamide is a type of vitamin B3. Animal experiments prove that nicotinamide can effectively promote diabetic wound healing, has great significance in treating diabetic gangrene, and has high safety and wide therapeutic window as a drug.

A compound for inducing male sterility of plant (paddy rice, wheat, cotton, etc) is disclosed, which is just the 3-carboxyl-4-pyranone. Its advantages are high efficiency (98% or more), high fruit bearing rate for hybridized seeds, and high selection index (more than 30).

The present invention discloses a compound injection in absolut ethyl alcohol or compound powdered injection preparation of prostaglandin E1, prostaglandin E1 potassium salt, prostaglandin E1 sodium salt or prostaglandin A1 and prostaglandin B1. The compound preparation is used in preventing and treating AIDS and abstaining from drugs. It has unique recipe, complementary components, determined curative effect and less toxic side effect.

The present invention discloses an application of balicatib in preparation of anti-filovirus infection drugs and comprises the application of the balicatib in prevention or treatment of the filovirusinfection or the combined application with other antiviral drugs.

The invention relates to an inhalant used for inhibiting coronavirus, and a preparation method and application of the inhalant, and belongs to the technical field of pharmaceutical preparations. The inhalant comprises Remdesivir and/or a pharmaceutically acceptable salt thereof. According to the inhalant used for inhibiting the coronavirus, due to adoption of small-dose pulmonary administration,effective pulmonary administration concentration can be achieved when micronized or aerosolized Remdesivir is inhaled, the coronavirus, especially the novel coronavirus, can be effectively inhibited, the defects of a narrow treatment window and poor safety in the prior art are overcome, a small dosage is given for multiple times, so that the inhalant can be accumulated in the lung so as to form an effective virus inhibition effect, a curative effect can be improved or the dosage of the Remdesivir is reduced, and potential side effects are reduced.

The present invention relates to a Chinese medicine for external application for curing ankylosing spondylitis. It is made up by mixing the following 8 Chinese medicinal materials: eucommia bark 40-50g. aconite main tuber 20-30g. turmeric 20-30g, dried ginger 20-30g, orient vine 20-30g, speranskia/balsam 20-30g, arisaema root 10-20g and dragon's blood 0.5-1g.

The invention discloses vaccine and a combination medicine for preventing tuberculosis, a method for preparing the vaccine and application, and belongs to the field of medicines for treating tuberculosis latent infection. By the aid of the vaccine with mycobacterium microbial compound adjuvants for preventing the tuberculosis, the problems of ineffectiveness or poor effects of existing subunit vaccine for treating tubercle bacillus latent infected population, diversified adjuvants, hypersensitivity and Koch reaction risks can be pertinently solved. The vaccine with mycobacterium microbial compound adjuvants for preventing the tuberculosis comprises Ag85b proteins, ESAT6-CFP10 proteins and mycobacterium vaccae thallus extract. The vaccine, the combination medicine, the method and the application have the advantages that the vaccine with the mycobacterium microbial compound adjuvants for preventing the tuberculosis is used for treating latent tuberculosis infection, and obvious effects can be realized; the vaccine only comprises a single type of adjuvants, and accordingly hypersensitivity and Koch reaction risks can be prevented.

The invention relates to a method for administrating preparations containing oseltamivir guanidyl carboxylate analogues and/or ethyl esters thereof. Administration is carried out through inhalation. The method can be used for treating cold caused by influenza viruses. By adopting the administration method provided by the invention, not only can dependence on the single variety of drugs such as oseltamivir, zanamivir and peramivir be reduced and new drug resistant virus strains generated by using the single variety in quantity be avoided but also the method which is favorable for greatly improving the bioavailability compared with oral administration or intravenous drip is provided for oseltamivir guanidyl carboxylate analogues or ethyl esters thereof; more importantly, the method which has the advantages of small drug dose, less side effects and high effect taking speed is provided.

The invention relates to a combination drug for treating cervical cancer, which is a preparation processed by mixing 85 to 95 percent of sodium valproate and 5 to 15 percent of all-trans retinoic acid, comprising an oral preparation, or external preparation, or vaginal suppository allowed by pharmacy. External cyto-inhibition experiment shows that the inhibition ratio of the combination drug is 56 percent which is higher than that of a cis-platinum group of 41 percent, an ATRA group of 30 percent and a VPA group of 1 percent. Animal experiments show that the effect of the combination drug for inhibiting tumor growth is obviously superior than the effect of monotherapy the VPA and the oral cis-platinum.

A Chinese medicine in the form of decoction or capsule for treating depression is prepared from Hyperici sampsonii and borneol.