Blood plasma fractions as a treatment for aging-associated cognitive disorders

A technology for cognitive impairment and pulp fractionation, applied in the fields of peptide/protein components, medical raw materials derived from mammals, medical preparations containing active ingredients, etc.

Active Publication Date: 2019-07-02
ALKAHEST INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Treatments for cognitive decline and neurodegenerative conditions have had limited success in preventing and reversing damage

Method used

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  • Blood plasma fractions as a treatment for aging-associated cognitive disorders
  • Blood plasma fractions as a treatment for aging-associated cognitive disorders
  • Blood plasma fractions as a treatment for aging-associated cognitive disorders

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Embodiment Construction

[0045] 1 Introduction

[0046] The present invention relates to the identification and discovery of methods and compositions for the treatment and / or prevention of cognitive impairment, including age-related dementia and neurodegenerative diseases. Methods and compositions for treating a subject with such disorders are described herein and are aspects of the invention. The methods and compositions described herein are useful for: preventing cognitive impairment, age-related dementia, and neurodegenerative diseases; ameliorating symptoms of cognitive impairment, age-related dementia, and neurodegenerative diseases; slowing aging-related cognition impairment, progression of age-related dementia, and neurodegenerative disease; and / or reversal of aging-related cognitive impairment, progression of age-related dementia, and neurodegenerative disease. Embodiments of the invention include the use of plasma fractions, such as one or more fractions or effluents obtained from a blood fr...

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Abstract

Methods and compositions for treating and / or preventing aging-related conditions are described. The compositions used in the methods include fractions derived from blood plasma with efficacy in treating and / or preventing aging-related conditions such as neurocognitive disorders.

Description

[0001] Cross References to Related Applications [0002] This application claims priority under 35 U.S.C. § 119(e) on the filing date of U.S. Provisional Patent Application No. 62 / 412,258, filed October 24, 2016; the disclosure of which is incorporated by reference This article. technical field [0003] The present invention relates to the prevention and treatment of aging-related diseases. The present invention relates to the use of blood products, such as plasma fractions, for the treatment and / or prevention of age-related conditions, such as neurocognitive disorders and neurodegenerative disorders. Background technique [0004] The following is provided as background information only and is not admitted to be prior art to the present invention. [0005] Aging is an important risk factor for a variety of human diseases, including cognitive impairment, cancer, arthritis, visual loss, osteoporosis, diabetes, cardiovascular disease, and stroke. In addition to normal synaps...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/38A61K35/16A61P25/28
CPCA61K38/38A61K35/16A61P25/28A61K38/385
Inventor 大卫·贝尔伊恩·加拉格尔史蒂文·P·布雷斯韦特S·樱井·南乌·丹格乔·麦克拉肯卡罗伊·尼科利希
Owner ALKAHEST INC
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