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Traditional Chinese medicine composition for treating human papilloma virus (HPV) infection and preparing method and application thereof

A technology of human papillomavirus and composition, which is applied in the field of traditional Chinese medicine composition, can solve problems such as difficulty in the development and verification of prevention and treatment drugs, pathogenicity, and inability to culture HPV virus in vitro, so as to improve the body's immunity, significant therapeutic effect, The effect of increasing the number

Inactive Publication Date: 2019-10-25
BEIJING PATBORN BIOTECH DEV CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The HPV virus can neither be cultured in vitro nor cause disease in other animals, so it has brought great difficulties to the development and verification of its prevention and treatment drugs

Method used

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  • Traditional Chinese medicine composition for treating human papilloma virus (HPV) infection and preparing method and application thereof
  • Traditional Chinese medicine composition for treating human papilloma virus (HPV) infection and preparing method and application thereof
  • Traditional Chinese medicine composition for treating human papilloma virus (HPV) infection and preparing method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Embodiment 1 Chinese medicine composition and its preparation

[0063] 1. Raw materials

[0064] In terms of parts by mass: 15 parts of Taoerqi, 18 parts of Magnolia officinalis, 18 parts of Polygonum cuspidatum, 25 parts of Licorice root, 11.5 parts of licorice, 25 parts of Kochia scoparia, 6.5 parts of Brucea javanica, 37.5 parts of Smilax cocos, 12.5 parts of Centella asiatica .

[0065] 2. Preparation method

[0066] (1) Alcohol extraction and concentration:

[0067] Weigh Taoerqi, Brucea javanica, Polygonum cuspidatum, Smilax cocos, Centella asiatica, Landing root.

[0068] Centella asiatica was extracted with 12 times the amount of 60% ethanol at room temperature and 150w ultrasonic conditions for 1 hour to obtain an extract, and the treated medicinal material was used for later use;

[0069] Use 6 times the amount of absolute ethanol to extract the tiger zucchini under ultrasonic conditions of 80°C and 200W ultrasonic power for 45 minutes to obtain an extract...

Embodiment 2

[0079] Embodiment 2 Chinese medicine composition and its preparation

[0080] The difference between this embodiment and embodiment 1 is:

[0081] The raw material medicine is weighed according to the following parts by mass: 8 parts of Taoerqi, 30 parts of Magnolia officinalis, 7.5 parts of Polygonum cuspidatum, 40 parts of Rhizoma chinensis, 3 parts of licorice, 40 parts of Kochia scoparia, 2.5 parts of Brucea javanica, 55 parts of Smilax cocos, Snow grass 5 parts.

[0082] The preparation method is the same as in Example 1.

Embodiment 3

[0083] Embodiment 3 Chinese medicine composition and preparation thereof

[0084] The difference between this embodiment and embodiment 1 is:

[0085] The raw materials are weighed according to the following parts by mass: 22 parts of Taoerqi, 7.5 parts of Magnolia officinalis, 30 parts of Polygonum cuspidatum, 10 parts of Rhizoma chinensis, 20 parts of licorice, 10 parts of Kochia fructus, 10 parts of Brucea javanica, 20 parts of Smilax cocos, Snow grass 20 parts.

[0086] The preparation method is the same as in Example 1.

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Abstract

The invention relates to traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for treating human papilloma virus (HPV) infection and a preparing method and application thereof. Effective components of the traditional Chinese medicine composition are derived from sinopodophyllum hexandrum, cortex magnoliae officinalis, rhizoma polygoni cuspidati, air-plant herb, liquorice root, fructus kochiae, fructus bruceae, rhizoma smilacis glabrae and herba centellae. The traditional Chinese medicine composition is combined with the clinical treatment effect and condyloma acuminate animal model tests to constantly adjust the use quantities of all active pharmaceutical ingredients in the formula, and full play is given to the compatibility andsynthesis effects of all the active pharmaceutical ingredients in the traditional Chinese medicine prescription. The traditional Chinese medicine composition can effectively remove the human papillomavirus, has a significant treatment effect on HPV low-risk infection and HR-HPV positive cervical intraepithelial neoplasia low-grade lesions, and can increase the number of langerhans cells, and thusthe immunity of the body is enhanced.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating human papillomavirus (HPV) infection, a preparation method and application thereof. Background technique [0002] HPV (Human papilloma virus, referred to as HPV), is a minimal DNA virus, mainly infects epithelial cells, and humans are the only host. So far, more than 200 HPV subtypes have been identified through comparison of viral DNA sequences. [0003] HPV mainly infects the host's epithelial cells and inner tissue cells. According to the shape of the infected tissue, it can be divided into two types: epidermal type and mucosal type. The epidermal type mainly causes epithelial infection of hands and feet; tract infection. The main diseases caused by HPV are: 1. Condyloma acuminatum, which mainly occurs in male and female genitals, perianal and other parts; 2. Verruca vulgaris, which mainly occurs in the face...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61P31/20A61P37/04A61P35/00A61K33/06A61K35/64
CPCA61K33/06A61K35/64A61K36/185A61K36/23A61K36/232A61K36/236A61K36/24A61K36/268A61K36/29A61K36/355A61K36/41A61K36/484A61K36/575A61K36/60A61K36/704A61K36/736A61K36/815A61K36/896A61K36/90A61K2236/331A61K2236/333A61P31/20A61P35/00A61P37/04A61K2300/00
Inventor 杜转社侯淑萍
Owner BEIJING PATBORN BIOTECH DEV CO LTD
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